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Index > Protein center > Pitrm1(Gene name) > Mouse
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  • Pitrm1 (Gene name),
  • Presequence protease, mitochondrial (Protein name ),  PREP_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Pitrm1(Kiaa1104;Ntup1);
    Protein name:
    Presequence protease, mitochondrial;
    Alternative:
    Pitrilysin metalloproteinase 1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.
    Subcellular Location:
    Mitochondrion matrix
    Protein Attributes:
    Sequence length:
    1036
    Sequence:
    50:
    MWRFSGRRGL | CAVQRLSCGR | VHHRVWREKS | DQACERALQY | KVGEKIHGFT | 
    100:
    VNQVTPVPEL | FLTAVKLSHD | NTGARYLHLA | REDKNNLFSV | QFRTTPMDST | 
    150:
    GVPHVLEHTV | LCGSQKYPCR | DPFFKMLNRS | LSTFMNAMTA | SDYTIYPFST | 
    200:
    QNPKDFQNLL | SVYLDATFFP | CLRELDFWQE | GWRLEHENPR | DPQTPLIFKG | 
    250:
    VVFNEMKGAF | TDNERIFSQH | LQNKLLPDHT | YSVVSGGDPL | CIPELTWEQL | 
    300:
    KQFHATHYHP | SNARFFTYGN | FQLEGHLKQI | HEEALSKFQR | LEQSTAVPAQ | 
    350:
    PHWDKPREFH | ITCGPDSLAT | ETAKQTTVSV | SFLLPDITDT | FEAFTLSLLS | 
    400:
    SLLIAGPNSP | FYKALIESGL | GTDFSPDVGY | NGYTREAYFS | VGLQGIAEKD | 
    450:
    VKTVRELVDR | TIEEVIEKGF | EDDRIEALLH | KIEIQTKHQS | ASFGLTLTSY | 
    500:
    IASCWNHDGD | PVELLQIGSQ | LTRFRKCLKE | NPKFLQEKVE | QYFKNNQHKL | 
    550:
    TLSMKPDDKY | YEKQTQMETE | KLEQKVNSLS | PADKQQIYEK | GLELQTQQSK | 
    600:
    HQDASCLPAL | KVSDIEPSMP | FTKLDIGLAA | GDIPVQYCPQ | PTNGMVYFRA | 
    650:
    FSSLNTLPED | LRPIVPLFCS | VLTKLGCGIL | NYREQAQQIE | LKTGGMSVTP | 
    700:
    HVLPDDSQLD | TYEQGVLFSS | LCLERNLPDM | MHLWSEIFNN | PCFEEEEHFK | 
    750:
    VLVKMTAQEL | SNGISDSGHL | YAALRASKTL | TPSGDLQETF | SGMDQVKVMK | 
    800:
    RIAEMTDIKP | ILRKLPRIKK | YLLNCDNMRC | SVNATPQQMP | QAEKEVENFL | 
    850:
    RNVGRSKKER | KPVRPHIVEK | PTPSGPSGAA | HVSGSQIVRK | LVTDPTFKPC | 
    900:
    QMKTHFVLPF | PVNYIGECVR | TVPYADPDHA | SLKILARLMT | AKFLHTEIRE | 
    950:
    KGGAYGGGAK | LTHSGIFTLY | SYRDPNSIET | LQSFGKAVDW | AKSGKFTQQD | 
    1000:
    IDEAKLSVFS | TVDSPVAPSD | KGMDHFLYGL | SDEMKQAYRE | QLFAVNHDKL | 
    1036:
    TSVSHKYLGI | GKSTHGLAIL | GPENSKIAKD | PSWIIK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    KEGG:
    SMR:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Presequence protease, mitochondrial
    ELISA Kit for Mouse Presequence protease, mitochondrial
    CLIA Kit for Mouse Presequence protease, mitochondrial
    CLIA Kit for Mouse Presequence protease, mitochondrial
    Polyclonal Antibody for Mouse Presequence protease, mitochondrial
    Polyclonal Antibody for Mouse Presequence protease, mitochondrial
    Monoclonal Antibody for Mouse Presequence protease, mitochondrial
    Monoclonal Antibody for Mouse Presequence protease, mitochondrial
    Protein for Mouse Presequence protease, mitochondrial
    Protein for Mouse Presequence protease, mitochondrial

    R&D Technical Data
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Expression profiling of placentomegaly associated with nuclear transplantation of mouse ES cells."
      Suemizu H. , Aiba K. , Yoshikawa T. , Sharov A.A. , Shimozawa N. , Tamaoki N. , Ko M.S.H.
      Dev. Biol.253:36-53(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);INDUCTION
      strain: C57BL/6J.
    2. 2.
      "Fine-mapping gene-by-diet interactions on chromosome 13 in a LG/J x SM/J murine model of obesity."
      Ehrich T.H. , Hrbek T. , Kenney-Hunt J.P. , Pletscher L.S. , Wang B. , Semenkovich C.F. , Cheverud J.M.
      Diabetes54:1863-1872(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANTS GLN-15; ILE-17; CYS-19; MET-462; LYS-546 AND VAL-583
      strain: LG/J.
      strain: SM/J.
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2 AND 3)
      strain: BALB/c.
      strain: C57BL/6J.
      tissue: Amnion.
      tissue: Tongue.
    4. 4.
      "Prediction of the coding sequences of mouse homologues of KIAA gene: III. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
      Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Koseki H. , Hiraoka S. , Saga Y. , Nagase T. , Ohara O. , Koga H.
      DNA Res.10:167-180(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 4-1036 (ISOFORM 1)
      tissue: Embryonic tail.
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 395-1036
      strain: FVB/N.
      tissue: Mammary tumor.
    6. 6.
      "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
      Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-759;SUCCINYLATION [LARGE SCALE ANALYSIS] AT LYS-770; LYS-848 AND LYS-945;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic fibroblast.
      tissue: Liver.
    7. 7.
      "Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways."
      Rardin M.J. , Newman J.C. , Held J.M. , Cusack M.P. , Sorensen D.J. , Li B. , Schilling B. , Mooney S.D. , Kahn C.R. , Verdin E. , Gibson B.W.
      Proc. Natl. Acad. Sci. U.S.A.110:6601-6606(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-770 AND LYS-883;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
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