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Index > Protein center > Prima1(Gene name) > Rat
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  • Prima1 (Gene name),
  • Proline-rich membrane anchor 1 (Protein name ),  PRIMA_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Prima1;
    Protein name:
    Proline-rich membrane anchor 1(PRiMA);
    Alternative:

    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with ACHE, probably through disulfide bonds.
    Function:
    Required to anchor acetylcholinesterase (ACHE) to the basal lamina of the neuromuscular junction and to the membrane of neuronal synapses in brain. Organizes ACHE into tetramers.
    Subcellular Location:
    Cell membrane Single-pass type I membrane protein Cell junction Cell junction synapse In the brain, PRIMA linked to ACHE is found in membrane rafts.
    Protein Attributes:
    Sequence length:
    153
    Sequence:
    50:
    MLLRDLVLRH | GCCWPSLLLH | CALHPLWGLV | QVTHAEPQKS | CSKVTDSCQH | 
    100:
    ICQCRPPPPL | PPPPPPPPPP | RLLSAPAPNS | TSCPAEDSWW | SGLVIIVAVV | 
    150:
    CASLVFLTVL | VIICYKAIKR | KPLRKDENGA | SVAEYPMSSS | PSNKGVDVNA | 
    153:
    AVV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat PRiMA
    ELISA Kit for Rat PRiMA
    ELISA Kit for Rat PRiMA
    CLIA Kit for Rat PRiMA
    CLIA Kit for Rat PRiMA
    CLIA Kit for Rat PRiMA
    Polyclonal Antibody for Rat PRiMA
    Polyclonal Antibody for Rat PRiMA
    Polyclonal Antibody for Rat PRiMA
    Monoclonal Antibody for Rat PRiMA
    Monoclonal Antibody for Rat PRiMA
    Monoclonal Antibody for Rat PRiMA
    Protein for Rat PRiMA
    Protein for Rat PRiMA
    Protein for Rat PRiMA

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      Kube M. , Klages S. , Kuhl H. , Thiel J. , Beck A. , Reinhardt R.
      Submitted (2008-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    2. 2.
      "Transcriptional regulation of proline-rich membrane anchor (PRiMA) of globular form acetylcholinesterase in neuron: an inductive effect of neuron differentiation."
      Xie H.Q. , Choi R.C. , Leung K.W. , Chen V.P. , Chu G.K. , Tsim K.W.
      Brain Res.1265:13-23(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    3. 3.
      "Targeting acetylcholinesterase to membrane rafts: a function mediated by the proline-rich membrane anchor (PRiMA) in neurons."
      Xie H.Q. , Liang D. , Leung K.W. , Chen V.P. , Zhu K.Y. , Chan W.K. , Choi R.C. , Massoulie J. , Tsim K.W.
      J. Biol. Chem.285:11537-11546(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ACHE TETRAMERS;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
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