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Index > Protein center > PRODH(Gene name) > Human
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  • PRODH (Gene name),
  • Proline dehydrogenase 1, mitochondrial (Protein name ),  PROD_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    PRODH(PIG6;POX2);
    Protein name:
    Proline dehydrogenase 1, mitochondrial;
    Alternative:
    Proline oxidase 2;Proline oxidase;p53-induced gene 6 protein;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Converts proline to delta-1-pyrroline-5-carboxylate.
    Subcellular Location:
    Mitochondrion matrix
    Protein Attributes:
    Sequence length:
    600
    Sequence:
    50:
    MALRRALPAL | RPCIPRFVQL | STAPASREQP | AAGPAAVPGG | GSATAVRPPV | 
    100:
    PAVDFGNAQE | AYRSRRTWEL | ARSLLVLRLC | AWPALLARHE | QLLYVSRKLL | 
    150:
    GQRLFNKLMK | MTFYGHFVAG | EDQESIQPLL | RHYRAFGVSA | ILDYGVEEDL | 
    200:
    SPEEAEHKEM | ESCTSAAERD | GSGTNKRDKQ | YQAHRAFGDR | RNGVISARTY | 
    250:
    FYANEAKCDS | HMETFLRCIE | ASGRVSDDGF | IAIKLTALGR | PQFLLQFSEV | 
    300:
    LAKWRCFFHQ | MAVEQGQAGL | AAMDTKLEVA | VLQESVAKLG | IASRAEIEDW | 
    350:
    FTAETLGVSG | TMDLLDWSSL | IDSRTKLSKH | LVVPNAQTGQ | LEPLLSRFTE | 
    400:
    EEELQMTRML | QRMDVLAKKA | TEMGVRLMVD | AEQTYFQPAI | SRLTLEMQRK | 
    450:
    FNVEKPLIFN | TYQCYLKDAY | DNVTLDVELA | RREGWCFGAK | LVRGAYLAQE | 
    500:
    RARAAEIGYE | DPINPTYEAT | NAMYHRCLDY | VLEELKHNAK | AKVMVASHNE | 
    550:
    DTVRFALRRM | EELGLHPADH | QVYFGQLLGM | CDQISFPLGQ | AGYPVYKYVP | 
    600:
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    UniGene:
    String:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Proline dehydrogenase 1, mitochondrial
    Cat.:
    E15325h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Proline dehydrogenase 1, mitochondrial
    Cat.:
    E15325m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Proline dehydrogenase 1, mitochondrial
    Cat.:
    E15325b
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Proline dehydrogenase 1, mitochondrial
    Cat.:
    U15325b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Proline dehydrogenase 1, mitochondrial
    Cat.:
    U15325m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Proline dehydrogenase 1, mitochondrial
    Cat.:
    U15325h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Proline dehydrogenase 1, mitochondrial
    Polyclonal Antibody for Human Proline dehydrogenase 1, mitochondrial
    Cat.:
    P15325Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Proline dehydrogenase 1, mitochondrial
    Cat.:
    P15325Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Proline dehydrogenase 1, mitochondrial
    Monoclonal Antibody for Human Proline dehydrogenase 1, mitochondrial
    Monoclonal Antibody for Human Proline dehydrogenase 1, mitochondrial
    Protein for Human Proline dehydrogenase 1, mitochondrial
    Protein for Human Proline dehydrogenase 1, mitochondrial
    Protein for Human Proline dehydrogenase 1, mitochondrial

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    Linearity
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    References
    1. 1.
      "A human homologue of the Drosophila melanogaster sluggish-A (proline oxidase) gene maps to 22q11.2, and is a candidate gene for type-I hyperprolinaemia."
      Campbell H.D. , Webb G.C. , Young I.G.
      Hum. Genet.101:69-74(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3)
      tissue: Brain.
    2. 2.
      "The gene encoding proline dehydrogenase modulates sensorimotor gating in mice."
      Gogos J.A. , Santha M. , Takacs Z. , Beck K.D. , Luine V. , Lucas L.R. , Nadler J.V. , Karayiorgou M.
      Nat. Genet.21:434-439(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3)
      tissue: Cerebellum.
      tissue: Kidney.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);ENZYME ACTIVITY;COFACTOR;VARIANTS VAL-167 AND ARG-521;CHARACTERIZATION OF VARIANTS VAL-167; TRP-185; GLN-185; MET-289; LEU-406; ASN-426; MET-427; HIS-431; PRO-441; CYS-453; SER-455; MET-466; THR-472; ARG-521 AND GLU-521
      tissue: Kidney.
    4. 4.
      "The DNA sequence of human chromosome 22."
      Dunham I. , Hunt A.R. , Collins J.E. , Bruskiewich R. , Beare D.M. , Clamp M. , Smink L.J. , Ainscough R. , Almeida J.P. , Babbage A.K. , Bagguley C. , Bailey J. , Barlow K.F. , Bates K.N. , Beasley O.P. , Bird C.P. , Blakey S.E. , Bridgeman A.M. , more...
      Nature402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2);VARIANT ARG-521
      tissue: Brain.
    6. 6.
      Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S. , Ohara O. , Nagase T. , Kikuno R.F.
      Submitted (2005-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 337-600 (ISOFORMS 1/2/3)
      tissue: Brain.
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 444-600;INDUCTION BY TP53
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MET-289; HIS-431; PRO-441; CYS-453; SER-455; THR-472 AND ARG-521;INVOLVEMENT IN HP-1
    9. 9.
      "Genetic variation at the 22q11 PRODH2/DGCR6 locus presents an unusual pattern and increases susceptibility to schizophrenia."
      Liu H. , Heath S.C. , Sobin C. , Roos J.L. , Galke B.L. , Blundell M.L. , Lenane M. , Robertson B. , Wijsman E.M. , Rapoport J.L. , Gogos J.A. , Karayiorgou M.
      Proc. Natl. Acad. Sci. U.S.A.99:3717-3722(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS LEU-406; MET-427; PRO-441; CYS-453; MET-466; THR-472 AND ARG-521;INVOLVEMENT IN SCZD4
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] SER-488
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ASN-275; HIS-431 AND ASP-444
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