Protein name:
Profilin-2 ;
Alternative:
Profilin II ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio.
Function:
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
Subcellular Location:
Cytoplasm
cytoskeleton
Protein Attributes:
50:
MAGWQSYVDN | LMCDGCCQEA | AIVGYCDAKY | VWAATAGGVF | QSITPAEIDV |
100:
IIGKDREGFF | TNGLTLGGKK | CSVIRDSLYV | DSDCTMDIRT | KSQGGEPTYN |
140:
VAVGRAGRVL | VFVMGKEGVH | GGGLNKKAYS | MAKYLRDSGF |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Bovine
Mouse
ELISA Kit for Rat Profilin-2
ELISA Kit for Rat Profilin-2
ELISA Kit for Rat Profilin-2
ELISA Kit for Rat Profilin-2
CLIA Kit for Rat Profilin-2
CLIA Kit for Rat Profilin-2
CLIA Kit for Rat Profilin-2
CLIA Kit for Rat Profilin-2
Polyclonal Antibody for Rat Profilin-2
Polyclonal Antibody for Rat Profilin-2
Polyclonal Antibody for Rat Profilin-2
Polyclonal Antibody for Rat Profilin-2
Monoclonal Antibody for Rat Profilin-2
Monoclonal Antibody for Rat Profilin-2
Monoclonal Antibody for Rat Profilin-2
Monoclonal Antibody for Rat Profilin-2
Protein for Rat Profilin-2
Protein for Rat Profilin-2
Protein for Rat Profilin-2
Protein for Rat Profilin-2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Profilin II is alternatively spliced, resulting in profilin isoforms that are differentially expressed and have distinct biochemical properties."
Lambrechts A.
,
Braun A.
,
Jonckheere V.
,
Aszodi A.
,
Lanier L.M.
,
Robbens J.
,
Van Colen I.
,
Vandekerckhove J.
,
Faessler R.
,
Ampe C.
Mol. Cell. Biol.20:8209-8219(2000)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Brain .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Brain .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 55-69; 92-105 AND 109-116;IDENTIFICATION BY MASS SPECTROMETRY
strain :
Sprague-Dawley .
tissue :
Hippocampus .
tissue :
Spinal cord .