Pdzrn3 ELISA Kit for Mouse(Mus musculus) | EIAab.comPdzrn3 ELISA Kit for Mouse(Mus musculus)

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Pdzrn3 (Gene name),

E3 ubiquitin-protein ligase PDZRN3 (Protein name ), PZRN3_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Pdzrn3(Kiaa1095;Semcap3);

Protein name:

E3 ubiquitin-protein ligase PDZRN3;

Alternative:

Semaphorin cytoplasmic domain-associated protein 3(Protein SEMACAP3);PDZ domain-containing RING finger protein 3;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with NLGN1 and EFNB2 (By similarity). Interacts with UBE2D2 and with MUSK via the first PDZ domain. In myotubes, the interaction between PDZRN3 and MUSK is enhanced upon agrin stimulation.

Function:

E3 ubiquitin-protein ligase. Plays an important role in regulating the surface level of MUSK on myotubes. Mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. Might contribute to terminal myogenic differentiation.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

1063

Sequence:

50:

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300:

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950:

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1050:

1063:

TRVYNSFLSV | TTV

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.321654

SMR:

Q69ZS0

KEGG:

mmu:55983

Pfam:

PF00595

String:

Q69ZS0

Uniprot:

Q69ZS0

FOR

ELISA Kit for Mouse E3 ubiquitin-protein ligase PDZRN3

CLIA Kit for Mouse E3 ubiquitin-protein ligase PDZRN3

Polyclonal Antibody for Mouse E3 ubiquitin-protein ligase PDZRN3

Monoclonal Antibody for Mouse E3 ubiquitin-protein ligase PDZRN3

Protein for Mouse E3 ubiquitin-protein ligase PDZRN3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Regulation of synaptic growth and maturation by a synapse-associated E3 ubiquitin ligase at the neuromuscular junction."
Lu Z. , Je H.S. , Young P. , Gross J. , Lu B. , Feng G.
J. Cell Biol.177:1077-1089(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);FUNCTION;INTERACTION WITH MUSK AND UBE2D2;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE;AUTOUBIQUITINATION;MUTAGENESIS OF CYS-18 AND CYS-38
2.

"Cloning and characterization of a novel PDZ domain containing protein interacting with the transmembrane semaphorin, M-semF."
Wang L.-H. , Strittmatter S.M.
Submitted (1999-02) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
3.

"Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Koseki H. , Hiraoka S. , Saga Y. , Seino S. , Nishimura M. , Kaisho T. , Hoshino K. , Kitamura H. , Nagase T. , Ohara O. , Koga H.
DNA Res.11:205-218(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 12-1063 (ISOFORM 1)
tissue: Fetal brain.
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 392-1063
strain: FVB/N.
tissue: Mammary tumor.
5.

"PDZRN3 (LNX3, SEMCAP3) is required for the differentiation of C2C12 myoblasts into myotubes."
Ko J.A. , Kimura Y. , Matsuura K. , Yamamoto H. , Gondo T. , Inui M.
J. Cell Sci.119:5106-5113(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DEVELOPMENTAL STAGE

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