Gene name:
MLLT3 (AF9;YEATS3) ;
Protein name:
Protein AF-9 ;
Alternative:
Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein ;ALL1-fused gene from chromosome 9 protein ;YEATS domain-containing protein 3 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with BCOR. Interacts with CBX8.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MASSCAVQVK | LELGHRAQVR | KKPTVEGFTH | DWMVFVRGPE | HSNIQHFVEK |
100:
VVFHLHESFP | RPKRVCKDPP | YKVEESGYAG | FILPIEVYFK | NKEEPRKVRF |
150:
DYDLFLHLEG | HPPVNHLRCE | KLTFNNPTED | FRRKLLKAGG | DPNRSIHTSS |
200:
SSSSSSSSSS | SSSSSSSSSS | SSSSSSSSSS | SSSSSSSSSS | TSFSKPHKLM |
250:
KEHKEKPSKD | SREHKSAFKE | PSRDHNKSSK | ESSKKPKENK | PLKEEKIVPK |
300:
MAFKEPKPMS | KEPKPDSNLL | TITSGQDKKA | PSKRPPISDS | EELSAKKRKK |
350:
SSSEALFKSF | SSAPPLILTC | SADKKQIKDK | SHVKMGKVKI | ESETSEKKKS |
400:
TLPPFDDIVD | PNDSDVEENI | SSKSDSEQPS | PASSSSSSSS | SFTPSQTRQQ |
450:
GPLRSIMKDL | HSDDNEEESD | EVEDNDNDSE | MERPVNRGGS | RSRRVSLSDG |
500:
SDSESSSASS | PLHHEPPPPL | LKTNNNQILE | VKSPIKQSKS | DKQIKNGECD |
550:
KAYLDELVEL | HRRLMTLRER | HILQQIVNLI | EETGHFHITN | TTFDFDLCSL |
568:
DKTTVRKLQS | YLETSGTS
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human Protein AF-9
ELISA Kit for Human Protein AF-9
CLIA Kit for Human Protein AF-9
CLIA Kit for Human Protein AF-9
Polyclonal Antibody for Human Protein AF-9
Polyclonal Antibody for Human Protein AF-9
Monoclonal Antibody for Human Protein AF-9
Monoclonal Antibody for Human Protein AF-9
Protein for Human Protein AF-9
Protein for Human Protein AF-9
R&D Technical Data
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Precision
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Recovery
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Linearity
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
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Nat. Genet.36:40-45(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue :
Brain .
tissue :
Synovium .
3.
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[
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[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.
Mural R.J.
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more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Testis .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH BCOR
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH CBX8
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-294 AND SER-483;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-288; SER-294 AND SER-483;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-412; SER-419 AND SER-429;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Leukemic T-cell .
12.
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Cited for : FUNCTION;IDENTIFICATION IN THE SEC COMPLEX
13.
"AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia."
Lin C.
,
Smith E.R.
,
Takahashi H.
,
Lai K.C.
,
Martin-Brown S.
,
Florens L.
,
Washburn M.P.
,
Conaway J.W.
,
Conaway R.C.
,
Shilatifard A.
Mol. Cell37:429-437(2010)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;IDENTIFICATION IN THE SEC COMPLEX
14.
"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V.
,
Vermeulen M.
,
Santamaria A.
,
Kumar C.
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Miller M.L.
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Mann M.
Sci. Signal.3:RA3-RA3(2010)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-483;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
15.
"The little elongation complex regulates small nuclear RNA transcription."
Smith E.R.
,
Lin C.
,
Garrett A.S.
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Thornton J.
,
Mohaghegh N.
,
Hu D.
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Jackson J.
,
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Eissenberg J.C.
,
Shilatifard A.
Mol. Cell44:954-965(2011)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION IN THE SEC COMPLEX
16.
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Cited for : REVIEW ON THE SUPER ELONGATION COMPLEX
17.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH ALKBH4
18.
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Cited for : STRUCTURE BY NMR OF 490-568 IN COMPLEX WITH AFF1