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Index > Protein center > ANMBP(Shorten name) > Human
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  • General Annotation
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  • General Annotation
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  • Shorten name:
    ANMBP;
    Antigen name:
    Homo sapiens;
    Alternative:

    General Annotation
    Sub Unit:
    Homodimer. Isoform 3 exists as a homodimer.
    Function:
    The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
    Location:
    Myelin membrane Peripheral membrane protein Cytoplasmic side Cytoplasmic side of myelin.
    Antigen Attributes:
    Formula:
    MGNHAGKRELNAEKASTNSETNRGESEKKRNLGELSRTTSEDNEVFGEADANQNNGTSSQDTAVTDSKRTADPKNAWQDAHPADPGSRPHLIRLFSRDAPGREDNTFKDRPSESDELQTIQEDSAATSESLDVMASQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFGGDRGAPKRGSGKDSHHPARTAHYGSLPQKSHGRTQDENPVVHFFKNIVTPRTPPPSQGKGRGLSLSRFSWGAEGQRPGFGYGGRASDYKSAHKGFKGVDAQGTLSKIFKLGGRDSRSGSPMARR
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    FOR
    ELISA Kit for Human Homo sapiens
    Cat.:
    E80539h
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Homo sapiens
    Cat.:
    U80539h
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Homo sapiens
    Cat.:
    P80539Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Homo sapiens
    Protein for Human Homo sapiens

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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