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Index > Protein center > Tfap2b(Gene name) > Mouse
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  • Tfap2b (Gene name),
  • Transcription factor AP-2-beta (Protein name ),  AP2B_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Tfap2b(Tcfap2b);
    Protein name:
    Transcription factor AP-2-beta(AP2-beta);
    Alternative:
    Activating enhancer-binding protein 2-beta;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Binds DNA as a dimer. Can form homodimers or heterodimers with other AP-2 family members. Interacts with CITED4. Interacts with UBE2I. Interacts with KCTD1; this interaction represses transcription activation. Interacts with CITED2 (via C-terminus); the interaction stimulates TFAP2B-transcriptional activity.
    Function:
    Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    459
    Sequence:
    50:
    MHSPPRDQAA | IMLWKLVENV | KYEDIYEDRH | DGVPSHSSRL | SQLGSVSQGP | 
    100:
    YSSAPPLSHT | PSSDFQPPYF | PPPYQPLPYH | QSQDPYSHVN | DPYSLNPLHQ | 
    150:
    PQQHPWGQRQ | RQEVGSEAGS | LLPQPRAALP | QLSGLDPRRD | YHSVRRPDVL | 
    200:
    LHSAHHGLDA | GMGDSLSLHG | LGHPGMEDVQ | SVEDANNSGM | NLLDQSVIKK | 
    250:
    VPVPPKSVTS | LMMNKDGFLG | GMSVNTGEVF | CSVPGRLSLL | SSTSKYKVTV | 
    300:
    GEVQRRLSPP | ECLNASLLGG | VLRRAKSKNG | GRSLRERLEK | IGLNLPAGRR | 
    350:
    KAANVTLLTS | LVEGEAVHLA | RDFGYICETE | FPAKAVSEYL | NRQHTDPSDL | 
    400:
    HSRKNMLLAT | KQLCKEFTDL | LAQDRTPIGN | SRPSPILEPG | IQSCLTHFSL | 
    450:
    ITHGFGAPAI | CAALTALQNY | LTEALKGMDK | MFLNNTTNRH | TSGEGPGSKT | 
    459:
    GDKEEKHRK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse AP2-beta
    Cat.:
    E0510h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse AP2-beta
    Cat.:
    E0510d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse AP2-beta
    Cat.:
    E0510m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse AP2-beta
    Cat.:
    U0510h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse AP2-beta
    Cat.:
    U0510d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse AP2-beta
    Cat.:
    U0510m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse AP2-beta
    Polyclonal Antibody for Mouse AP2-beta
    Cat.:
    P0510Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse AP2-beta
    Cat.:
    P0510Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse AP2-beta
    Monoclonal Antibody for Mouse AP2-beta
    Monoclonal Antibody for Mouse AP2-beta
    Protein for Mouse AP2-beta
    Protein for Mouse AP2-beta
    Protein for Mouse AP2-beta

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning and characterization of a second AP-2 transcription factor: AP-2 beta."
      Moser M. , Imhof A. , Pscherer A. , Bauer R. , Amselgruber W. , Sinowatz F. , Schule R. , Buettner R.
      Development121:2779-2788(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: BALB/c.
      tissue: Embryo.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Head.
    3. 3.
      "Cloning of mouse Cited4, a member of the CITED family p300/CBP-binding transcriptional coactivators: induced expression in mammary epithelial cells."
      Yahata T. , Takedatsu H. , Dunwoodie S.L. , Braganca J. , Swingler T. , Withington S.L. , Hur J. , Coser K.R. , Isselbacher K.J. , Bhattacharya S. , Shioda T.
      Genomics80:601-613(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CITED4
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