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Index > Protein center > Apba1(Gene name) > Mouse
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  • Apba1 (Gene name),
  • Amyloid beta A4 precursor protein-binding family A member 1 (Protein name ),  APBA1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Apba1(Mint1;X11);
    Protein name:
    Amyloid beta A4 precursor protein-binding family A member 1;
    Alternative:
    Neuron-specific X11 protein;Adapter protein X11alpha;Neuronal Munc18-1-interacting protein 1(Mint-1);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Part of a multimeric complex containing Munc18-1 and syntaxin-1. Also part of the brain-specific heterotrimeric complex LIN-10/X11-alpha, LIN-2/CASK, and LIN7. Binds to the cytoplasmic domain of amyloid protein (APP) (By similarity). Interacts (via PDZ 1 and 2 domains) with FSPB (By similarity). Isoform 3 interacts (via its truncated PID domain) with active, GTP-bound RAB6A. Also interacts with GTP-bound RAB6B.
    Function:
    Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-AAP.
    Subcellular Location:
    Isoform 3 Golgi apparatus
    Protein Attributes:
    Sequence length:
    842
    Sequence:
    50:
    MNHLEGSAEV | EVADEAPGGE | VNESVEADLE | HPEVVEGQQP | SPSPPPPAGH | 
    100:
    EPEDHRGHPA | PPPPPPPQEE | EEEERGECLA | RSASTESGFH | NHTDTAEGDV | 
    150:
    LAAARDGYEA | ERAQDADDES | AYAVQYRPEA | EEYTEQAEAE | HVEAAQRRAL | 
    200:
    PNHLHFHSLE | HEEAMNAAYS | GYVYTHRLFH | RAEDEPYAEP | YADYGGLQEH | 
    250:
    VYEEIGDAPE | LEARDGLRLY | ERERDEAAAY | RQEALGARLH | HYDERSDGES | 
    300:
    DSPEKEAEFA | PYPRMDSYEQ | EEDIDQIVAE | VKQSMSSQSL | DKAAEDMPEA | 
    350:
    EQDLERAPTP | GGGHPDSPGL | PAPAGQQQRV | VGTPGGSEVG | QRYSKEKRDA | 
    400:
    ISLAIKDIKE | AIEEVKTRTI | RSPYTPDEPK | EPIWVMRQDI | SPTRDCDDQR | 
    450:
    PVDGDSPSPG | SSSPLGAESS | SIPLHPGDPT | EASTNKESRK | SLASFPTYVE | 
    500:
    VPGPCDPEDL | IDGIIFAANY | LGSTQLLSDK | TPSKNVRMMQ | AQEAVSRIKT | 
    550:
    AQKLAKSRKK | APEGESQPMT | EVDLFISTQR | IKVLNADTQE | PMMDHPLRTI | 
    600:
    SYIADIGNIV | VLMARRRMPR | SNSQENVEAS | HPSQDGKRQY | KMICHVFESE | 
    650:
    DAQLIAQSIG | QAFSVAYQEF | LRANGINPED | LSQKEYSDLL | NTQDMYNDDL | 
    700:
    IHFSKSENCK | DVFIEKQKGE | ILGVVIVESG | WGSILPTVII | ANMMHGGPAE | 
    750:
    KSGKLNIGDQ | IMSINGTSLV | GLPLSTCQSI | IKGLKNQSRV | KLNIVRCPPV | 
    800:
    TTVLIRRPDL | RYQLGFSVQN | GIICSLMRGG | IAERGGVRVG | HRIIEINGQS | 
    842:
    VVATPHEKIV | HILSNAVGEI | HMKTMPAAMY | RLLTAQEQPV | YI
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Amyloid beta A4 precursor protein-binding family A member 1
    Cat.:
    E10313r
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse Amyloid beta A4 precursor protein-binding family A member 1
    Cat.:
    E10313h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Amyloid beta A4 precursor protein-binding family A member 1
    Cat.:
    E10313m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Amyloid beta A4 precursor protein-binding family A member 1
    Cat.:
    U10313h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Amyloid beta A4 precursor protein-binding family A member 1
    Cat.:
    U10313m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Amyloid beta A4 precursor protein-binding family A member 1
    Cat.:
    U10313r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Amyloid beta A4 precursor protein-binding family A member 1
    Cat.:
    P10313Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Amyloid beta A4 precursor protein-binding family A member 1
    Cat.:
    P10313Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Amyloid beta A4 precursor protein-binding family A member 1
    Cat.:
    P10313Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Amyloid beta A4 precursor protein-binding family A member 1
    Monoclonal Antibody for Mouse Amyloid beta A4 precursor protein-binding family A member 1
    Monoclonal Antibody for Mouse Amyloid beta A4 precursor protein-binding family A member 1
    Protein for Mouse Amyloid beta A4 precursor protein-binding family A member 1
    Protein for Mouse Amyloid beta A4 precursor protein-binding family A member 1
    Protein for Mouse Amyloid beta A4 precursor protein-binding family A member 1

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    Linearity
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      strain: C57BL/6J.
      tissue: Olfactory bulb.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    3. 3.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
    5. 5.
      "A new Mint1 isoform, but not the conventional Mint1, interacts with the small GTPase Rab6."
      Thyrock A. , Ossendorf E. , Stehling M. , Kail M. , Kurtz T. , Pohlentz G. , Waschbusch D. , Eggert S. , Formstecher E. , Muthing J. , Dreisewerd K. , Kins S. , Goud B. , Barnekow A.
      PLoS ONE8:E64149-E64149(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 498-525 (ISOFORM 3);INTERACTION WITH RAB6A;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
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