Gene name:
Acvr2a (Acvr2) ;
Protein name:
Activin receptor type-2A ;
Alternative:
Activin receptor type IIA (ACTR-IIA) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with AIP1. Part of a complex consisting of AIP1, ACVR2A, ACVR1B and SMAD3.
Function:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MGAAAKLAFA | VFLISCSSGA | ILGRSETQEC | LFFNANWERD | RTNQTGVEPC |
100:
YGDKDKRRHC | FATWKNISGS | IEIVKQGCWL | DDINCYDRTD | CIEKKDSPEV |
150:
YFCCCEGNMC | NEKFSYFPEM | EVTQPTSNPV | TPKPPYYNIL | LYSLVPLMLI |
200:
AGIVICAFWV | YRHHKMAYPP | VLVPTQDPGP | PPPSPLLGLK | PLQLLEVKAR |
250:
GRFGCVWKAQ | LLNEYVAVKI | FPIQDKQSWQ | NEYEVYSLPG | MKHENILQFI |
300:
GAEKRGTSVD | VDLWLITAFH | EKGSLSDFLK | ANVVSWNELC | HIAETMARGL |
350:
AYLHEDIPGL | KDGHKPAISH | RDIKSKNVLL | KNNLTACIAD | FGLALKFEAG |
400:
KSAGDTHGQV | GTRRYMAPEV | LEGAINFQRD | AFLRIDMYAM | GLVLWELASR |
450:
CTAADGPVDE | YMLPFEEEIG | QHPSLEDMQE | VVVHKKKRPV | LRDYWQKHAG |
500:
MAMLCETIEE | CWDHDAEARL | SAGCVGERIT | QMQRLTNIIT | TEDIVTVVTM |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Rat
Bovine
Chicken
ELISA Kit for Mouse Activin receptor type-2A
ELISA Kit for Mouse Activin receptor type-2A
ELISA Kit for Mouse Activin receptor type-2A
ELISA Kit for Mouse Activin receptor type-2A
ELISA Kit for Mouse Activin receptor type-2A
CLIA Kit for Mouse Activin receptor type-2A
CLIA Kit for Mouse Activin receptor type-2A
CLIA Kit for Mouse Activin receptor type-2A
CLIA Kit for Mouse Activin receptor type-2A
CLIA Kit for Mouse Activin receptor type-2A
Polyclonal Antibody for Mouse Activin receptor type-2A
Polyclonal Antibody for Mouse Activin receptor type-2A
Polyclonal Antibody for Mouse Activin receptor type-2A
Polyclonal Antibody for Mouse Activin receptor type-2A
Polyclonal Antibody for Mouse Activin receptor type-2A
Monoclonal Antibody for Mouse Activin receptor type-2A
Monoclonal Antibody for Mouse Activin receptor type-2A
Monoclonal Antibody for Mouse Activin receptor type-2A
Monoclonal Antibody for Mouse Activin receptor type-2A
Monoclonal Antibody for Mouse Activin receptor type-2A
Protein for Mouse Activin receptor type-2A
Protein for Mouse Activin receptor type-2A
Protein for Mouse Activin receptor type-2A
Protein for Mouse Activin receptor type-2A
Protein for Mouse Activin receptor type-2A
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (1.5 ANGSTROMS) OF 25-121
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DISULFIDE BONDS IN EXTRACELLULAR DOMAIN
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH AIP1;IDENTIFICATION IN A COMPLEX WITH ACVR1B; AIP1 AND SMAD3