CAPRIN1 Polyclonal Antibody for Human(Homo sapiens) | EIAab.comCAPRIN1 Polyclonal Antibody for Human(Homo sapiens)

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Index > Protein center > CAPRIN1(Gene name) > Human

CAPRIN1 (Gene name),

Caprin-1 (Protein name ), CAPR1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CAPRIN1(GPIAP1;GPIP137;M11S1;RNG105);

Protein name:

Caprin-1;

Alternative:

Cytoplasmic activation- and proliferation-associated protein 1;Cell cycle-associated protein 1;GPI-anchored protein p137(GPI-p137;p137GPI);GPI-anchored membrane protein 1;RNA granule protein 105;Membrane component chromosome 11 surface marker 1;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

May form homomultimers. Directly interacts with G3BP1 in cytoplasmic RNA granules. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.

Function:

May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types.

Subcellular Location:

Cytoplasm cytosol Cell projection dendrite Associated with RNA granules.

Protein Attributes:

Sequence length:

709

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

709:

PQMNTQQVN

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:4076

Pfam:

PF12287

STRING:

9606.ENSP00000340329

UniGene:

Hs.471818

String:

Q14444

MIM:

601178

Uniprot:

Q14444

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ELISA Kit for Human Caprin-1

Cat.:

E14581h

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96T

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ELISA Kit for Human Caprin-1

Cat.:

E14581r

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96T

ELISA Kit for Human Caprin-1

Cat.:

E14581b

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96T

ELISA Kit for Human Caprin-1

Cat.:

E14581m

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96T

CLIA Kit for Human Caprin-1

Cat.:

U14581h

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96T

CLIA Kit for Human Caprin-1

Cat.:

U14581b

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96T

CLIA Kit for Human Caprin-1

Cat.:

U14581m

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Packing:

96T

CLIA Kit for Human Caprin-1

Cat.:

U14581r

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96T

Polyclonal Antibody for Human Caprin-1

Cat.:

P14581Rb-r

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40ug/0.2ml

Polyclonal Antibody for Human Caprin-1

Cat.:

P14581Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Caprin-1

Cat.:

P14581Rb-m

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Caprin-1

Protein for Human Caprin-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Identification and characterization of a novel protein (p137) which transcytoses bidirectionally in Caco-2 cells."
Ellis J.A. , Luzio J.P.
J. Biol. Chem.270:20717-20723(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT ASP-263
tissue: Colon.
2.

"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Taylor T.D. , Noguchi H. , Totoki Y. , Toyoda A. , Kuroki Y. , Dewar K. , Lloyd C. , Itoh T. , Takeda T. , Kim D.-W. , She X. , Barlow K.F. , Bloom T. , Bruford E. , Chang J.L. , Cuomo C.A. , Eichler E. , FitzGerald M.G. , more...
Nature440:497-500(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Eye.
5.

"The gene encoding the GPI-anchored membrane protein p137GPI (M11S1) maps to human chromosome 11p13 and is highly conserved in the mouse."
Gessler M. , Klant B. , Tsaoussidou S. , Ellis J.A. , Luzio J.P.
Genomics32:169-170(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 29-72
6.

Bienvenut W.V. , Heiserich L. , Boulahbel H. , Gottlieb E.
Submitted (2007-07) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 56-63; 88-110; 115-125; 148-158; 298-310 AND 634-660;IDENTIFICATION BY MASS SPECTROMETRY
tissue: Colon carcinoma.
7.

"Activation/division of lymphocytes results in increased levels of cytoplasmic activation/proliferation-associated protein-1: prototype of a new family of proteins."
Grill B. , Wilson G.M. , Zhang K.-X. , Wang B. , Doyonnas R. , Quadroni M. , Schrader J.W.
J. Immunol.172:2389-2400(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION (ISOFORMS 1 AND 2);SUBCELLULAR LOCATION;MULTIMERIZATION
8.

"Distinct structural features of caprin-1 mediate its interaction with G3BP-1 and its induction of phosphorylation of eukaryotic translation initiation factor 2alpha, entry to cytoplasmic stress granules, and selective interaction with a subset of mRNAs."
Solomon S. , Xu Y. , Wang B. , David M.D. , Schubert P. , Kennedy D. , Schrader J.W.
Mol. Cell. Biol.27:2324-2342(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH G3BP1;MRNA-BINDING;MUTAGENESIS OF ARG-612; ARG-633 AND ARG-690
9.

"RNA granule protein 140 (RNG140), a paralog of RNG105 localized to distinct RNA granules in neuronal dendrites in the adult vertebrate brain."
Shiina N. , Tokunaga M.
J. Biol. Chem.285:24260-24269(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION
10.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
11.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-10;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
12.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
13.

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT PRO-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
14.

"Characterization of O-GlcNAc cycling and proteomic identification of differentially O-GlcNAcylated proteins during G1/S transition."
Drougat L. , Olivier-Van Stichelen S. , Mortuaire M. , Foulquier F. , Lacoste A.S. , Michalski J.C. , Lefebvre T. , Vercoutter-Edouart A.S.
Biochim. Biophys. Acta1820:1839-1848(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION

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