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Index > Protein center > Casq1(Gene name) > Rat
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  • Casq1 (Gene name),
  • Calsequestrin-1 (Protein name ),  CASQ1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Casq1;
    Protein name:
    Calsequestrin-1;
    Alternative:
    Calsequestrin, skeletal muscle isoform;Aspartactin;Laminin-binding protein;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. The release of calcium bound to calsequestrin through a calcium release channel triggers muscle contraction. Binds 40 to 50 moles of calcium. Also binds laminin.
    Subcellular Location:
    Sarcoplasmic reticulum lumen This isoform of calsequestrin occurs in the sarcoplasmic reticulum's terminal cisternae luminal spaces of fast skeletal muscle cells. Aspartactin is found in the basal lamina surrounding individual muscle fibers.
    Protein Attributes:
    Sequence length:
    406
    Sequence:
    50:
    MRATDRMGAR | AVSKLRLALL | FVLVLGTPRS | GVQGEDGLDF | PEYDGVDRVI | 
    100:
    NVNAKNYKNV | FKKYEVLALL | YHEPPEDDKA | SQRQFEMEEL | ILELAAQVLE | 
    150:
    DKGVGFGLVD | SEKDAAVAKK | LGLTEEDSVY | VFKGDEVIEY | DGEFSADTLV | 
    200:
    EFLLDVLEDP | VELIEGEREL | QAFENIEDEI | KLIGYFKSKD | SEHYKAYEDA | 
    250:
    AEEFHPYIPF | FATFDSKVAK | KLTLKLNEID | FYEAFMEEPV | TIPDKPNSEE | 
    300:
    EIVSFVEEHR | RSTLRKLKPE | SMYETWEDDL | DGIHIVAFAE | EADPDGYEFL | 
    350:
    ETLKAVAQDN | TENPDLSIIW | IDPDDFPLLV | PYWEKTFDID | LSAPQIGVVN | 
    400:
    VTDADSIWME | MDDEEDLPSA | EELEDWLEDV | LEGEINTEDD | DDDDDDDDDD | 
    406:
    DDDDDD
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Calsequestrin-1
    Cat.:
    E15017h
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    96T
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    ELISA Kit for Rat Calsequestrin-1
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    E15017m
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    Packing:
    96T
    ELISA Kit for Rat Calsequestrin-1
    Cat.:
    E15017r
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    96T
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    ELISA Kit for Rat Calsequestrin-1
    Cat.:
    E15017d
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Rat Calsequestrin-1
    MSDS:
    Please sign in first.
    CLIA Kit for Rat Calsequestrin-1
    Cat.:
    U15017r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Calsequestrin-1
    Cat.:
    U15017m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Calsequestrin-1
    Cat.:
    U15017h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Calsequestrin-1
    MSDS:
    Please sign in first.
    CLIA Kit for Rat Calsequestrin-1
    Cat.:
    U15017d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Calsequestrin-1
    Cat.:
    P15017Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Calsequestrin-1
    Polyclonal Antibody for Rat Calsequestrin-1
    Polyclonal Antibody for Rat Calsequestrin-1
    Cat.:
    P15017Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Calsequestrin-1
    Cat.:
    P15017Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Calsequestrin-1
    Monoclonal Antibody for Rat Calsequestrin-1
    Monoclonal Antibody for Rat Calsequestrin-1
    Monoclonal Antibody for Rat Calsequestrin-1
    Monoclonal Antibody for Rat Calsequestrin-1
    Protein for Rat Calsequestrin-1
    Protein for Rat Calsequestrin-1
    Protein for Rat Calsequestrin-1
    Protein for Rat Calsequestrin-1
    Protein for Rat Calsequestrin-1

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    References
    1. 1.
      "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Gibbs R.A. , Weinstock G.M. , Metzker M.L. , Muzny D.M. , Sodergren E.J. , Scherer S. , Scott G. , Steffen D. , Worley K.C. , Burch P.E. , Okwuonu G. , Hines S. , Lewis L. , Deramo C. , Delgado O. , Dugan-Rocha S. , Miner G. , Morgan M. , more...
      Nature428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Brown Norway.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-163
      tissue: Prostate.
    3. 3.
      "Isolation and characterization of a laminin-binding protein from rat and chick muscle."
      Hall D.E. , Frazer K.A. , Hann B.C. , Reichardt L.F.
      J. Cell Biol.107:687-697(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 35-54;TISSUE SPECIFICITY
    4. 4.
      "Calsequestrin is a component of smooth muscles: the skeletal- and cardiac-muscle isoforms are both present, although in highly variable amounts and ratios."
      Volpe P. , Martini A. , Furlan S. , Meldolesi J.
      Biochem. J.301:465-469(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 35-54;TISSUE SPECIFICITY;FUNCTION
      strain: Wistar.
      tissue: Aorta.
      tissue: Stomach.
      tissue: Vas deferens.
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