C8a Polyclonal Antibody for Mouse(Mus musculus) | EIAab.comC8a Polyclonal Antibody for Mouse(Mus musculus)

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C8a (Gene name),

Complement component C8 alpha chain (Protein name ), CO8A_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

C8a;

Protein name:

Complement component C8 alpha chain;

Alternative:

Complement component 8 subunit alpha;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Heterotrimer of 3 chains: alpha, beta and gamma. The alpha and gamma chains are disulfide bonded. Component of the membrane attack complex (MAC). MAC assembly is initiated by protelytic cleavage of C5 into C5a and C5b. C5b binds sequentially C6, C7, C8 and multiple copies of the pore-forming subunit C9.

Function:

Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C8A inserts into the target membrane, but does not form pores by itself.

Subcellular Location:

Secreted Cell membrane Multi-pass membrane protein Secreted as soluble protein. Inserts into the cell membrane of target cells.

Protein Attributes:

Sequence length:

587

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

587:

WSECRGGSQE | RRRQCNNPPP | KNGGTPCLGR | NLQTQAC

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q8K182

SMR:

Q8K182

Pfam:

PF00057

UniGene:

Mm.197638

KEGG:

mmu:230558

Uniprot:

Q8K182

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ELISA Kit for Mouse Complement component C8 alpha chain

MSDS:

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ELISA Kit for Mouse Complement component C8 alpha chain

Cat.:

E1970h

Price:

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Manual:

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Packing:

96T

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ELISA Kit for Mouse Complement component C8 alpha chain

Cat.:

E1970m

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Complement component C8 alpha chain

Cat.:

U1970m

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Complement component C8 alpha chain

Cat.:

U1970h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Mouse Complement component C8 alpha chain

MSDS:

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Polyclonal Antibody for Mouse Complement component C8 alpha chain

Cat.:

P1970Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Complement component C8 alpha chain

Cat.:

P1970Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse Complement component C8 alpha chain

Protein for Mouse Complement component C8 alpha chain

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Two mouse strains with complementary mutations on the 8th complement."
Tanaka S. , Kikkawa Y. , Hosonuma M.I. , Koike S. , Yonekawa H.
Submitted (2002-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: BALB/c.
strain: DBA/2J.
strain: Mae/Stm.
tissue: Liver.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: FVB/N.
tissue: Liver.

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