Cspg4 Polyclonal Antibody for Rat(Rattus norvegicus) | EIAab.comCspg4 Polyclonal Antibody for Rat(Rattus norvegicus)

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Cspg4 (Gene name),

Chondroitin sulfate proteoglycan 4 (Protein name ), CSPG4_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Cspg4(Ng2);

Protein name:

Chondroitin sulfate proteoglycan 4;

Alternative:

HSN tumor-specific antigen;Chondroitin sulfate proteoglycan NG2;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with GRIP1, GRIP2 and GRIA2. Forms a ternary complex with GRIP1 and GRIA2. Interacts with ITGA4 through its chondroitin sulfate glycosaminoglycan. Interacts with BCAR1, CDC42 and ACK1. Interacts with MMP16 (By similarity). Interacts with the first PDZ domain of MPDZ. Interacts with PRKCA. Interacts with LGALS3 and the integrin composed of ITGB1 and ITGA3. Binds TNC, laminin-1, COL5A1 and COL6A2. Interacts with PLG and angiostatin. Binds FGF2 and PDGFA.

Function:

Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N-terminus growth factors, extracellular matrix proteases modulating their activity. May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. May modulate the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin. Functions also as a signal transducing protein by binding through its cytoplasmic C-terminus scaffolding and signaling proteins. May promote retraction fiber formation and cell polarization through Rho GTPase activation. May stimulate alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42, ACK1 and BCAR1. May activate FAK and ERK1/ERK2 signaling cascades.

Subcellular Location:

Cell membrane Single-pass type I membrane protein Extracellular side Apical cell membrane Single-pass type I membrane protein Extracellular side Cell projection lamellipodium membrane Single-pass type I membrane protein Extracellular side Localizes to the plasma membrane of oligodendrocytes (By similarity). Localized at the apical plasma membrane it relocalizes to the lamellipodia of astrocytoma upon phosphorylation by PRKCA. Localizes to the retraction fibers. A fraction may undergo cell surface proteolysis and secretion.

Protein Attributes:

Sequence length:

2326

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2326:

GGQPDPELLQ | FCRTPNPALR | NGQYWV

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

rno:81651

String:

Q00657

STRING:

10116.ENSRNOP00000023326

UniGene:

Rn.10381

Pfam:

PF00054

Uniprot:

Q00657

FOR

ELISA Kit for Rat Chondroitin sulfate proteoglycan 4

Cat.:

E2136h

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Packing:

96T

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ELISA Kit for Rat Chondroitin sulfate proteoglycan 4

Cat.:

E2136m

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Packing:

96T

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ELISA Kit for Rat Chondroitin sulfate proteoglycan 4

Cat.:

E2136r

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Packing:

96T

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CLIA Kit for Rat Chondroitin sulfate proteoglycan 4

Cat.:

U2136h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Rat Chondroitin sulfate proteoglycan 4

Cat.:

U2136m

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MSDS:

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Packing:

96T

CLIA Kit for Rat Chondroitin sulfate proteoglycan 4

Cat.:

U2136r

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat Chondroitin sulfate proteoglycan 4

Cat.:

P2136Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Chondroitin sulfate proteoglycan 4

Cat.:

P2136Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Chondroitin sulfate proteoglycan 4

Cat.:

P2136Rb-r

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat Chondroitin sulfate proteoglycan 4