Cyr61 Polyclonal Antibody for Mouse(Mus musculus) | EIAab.comCyr61 Polyclonal Antibody for Mouse(Mus musculus)

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Cyr61 (Gene name),

Protein CYR61 (Protein name ), CYR61_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Cyr61(Ccn1;Igfbp10);

Protein name:

Protein CYR61;

Alternative:

CCN family member 1;3CH61;Insulin-like growth factor-binding protein 10(IBP-10;IGF-binding protein 10;IGFBP-10);Cysteine-rich angiogenic inducer 61;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interaction with integrins is heparin- and cell-type-dependent and promotes cell adhesion.

Function:

Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5 (By similarity). CYR61-mediated gene regulation is dependent on heparin-binding (By similarity). Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1 (By similarity). Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-1/beta-5 and cell proliferation through integrin alpha-v/beta-3.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

379

Sequence:

50:

100:

150:

200:

250:

300:

350:

379:

CKCNYNCPHP | NEASFRLYSL | FNDIHKFRD

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P18406

Pfam:

PF00007

STRING:

10090.ENSMUSP00000029846

KEGG:

mmu:16007

UniGene:

Mm.1231

SMR:

P18406

Uniprot:

P18406

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ELISA Kit for Mouse Protein CYR61

Cat.:

E0494r

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Packing:

96T

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ELISA Kit for Mouse Protein CYR61

Cat.:

E0494m

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96T

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ELISA Kit for Mouse Protein CYR61

Cat.:

E0494h

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96T

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ELISA Kit for Mouse Protein CYR61

Cat.:

E0494c

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Packing:

96T

CLIA Kit for Mouse Protein CYR61

Cat.:

U0494h

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Manual:

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96T

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CLIA Kit for Mouse Protein CYR61

Cat.:

U0494m

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Protein CYR61

Cat.:

U0494c

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Protein CYR61

Cat.:

U0494r

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse Protein CYR61

Cat.:

P0494Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Protein CYR61

Cat.:

P0494Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Protein CYR61

Cat.:

P0494Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Protein CYR61

Monoclonal Antibody for Mouse Protein CYR61

Protein for Mouse Protein CYR61

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Expression of cyr61, a growth factor-inducible immediate-early gene."
O'Brien T.P. , Yang G.P. , Sanders L. , Lau L.F.
Mol. Cell. Biol.10:3569-3577(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: BALB/c.
tissue: Fibroblast.
2.

"Promoter function and structure of the growth factor-inducible immediate early gene cyr61."
Latinkic B.V. , O'Brien T.P. , Lau L.F.
Nucleic Acids Res.19:3261-3267(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
strain: A/J.
tissue: Embryonic fibroblast.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6.
tissue: Brain.
4.

"Adhesion of human skin fibroblasts to Cyr61 is mediated through integrin alpha 6beta 1 and cell surface heparan sulfate proteoglycans."
Chen N. , Chen C.-C. , Lau L.F.
J. Biol. Chem.275:24953-24961(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: HEPARIN-BINDING DOMAIN

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