Mlycd Polyclonal Antibody for Rat(Rattus norvegicus) | EIAab.comMlycd Polyclonal Antibody for Rat(Rattus norvegicus)

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Mlycd (Gene name),

Malonyl-CoA decarboxylase, mitochondrial (Protein name ), DCMC_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Mlycd;

Protein name:

Malonyl-CoA decarboxylase, mitochondrial(MCD);

Alternative:

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

N/A

Function:

Catalyzes the conversion of malonyl-CoA to acetyl-CoA. In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid synthase and that fatty acids with multiple methyl side chains are produced.

Subcellular Location:

Mitochondrion Cytoplasm Peroxisome

Protein Attributes:

Sequence length:

492

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

492:

VNYRYYLEET | GPNSISYLGS | KNIKASEQIL | SLVAQFQSNS | KL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.13468

KEGG:

rno:85239

String:

Q920F5

Pfam:

PF05292

STRING:

10116.ENSRNOP00000019923

Uniprot:

Q920F5

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ELISA Kit for Rat MCD

Cat.:

E9335m

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Rat MCD

Cat.:

E9335r

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MSDS:

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Packing:

96T

ELISA Kit for Rat MCD

Cat.:

E9335h

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MSDS:

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Packing:

96T

CLIA Kit for Rat MCD

Cat.:

U9335m

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MSDS:

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Packing:

96T

CLIA Kit for Rat MCD

Cat.:

U9335r

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MSDS:

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Packing:

96T

CLIA Kit for Rat MCD

Cat.:

U9335h

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat MCD

Cat.:

P9335Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat MCD

Cat.:

P9335Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat MCD

Cat.:

P9335Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Rat MCD

Protein for Rat MCD

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning and expression of rat pancreatic beta-cell malonyl-CoA decarboxylase."
Voilley N. , Roduit R. , Vicaretti R. , Bonny C. , Waeber G. , Dyck J.R. , Lopaschuk G.D. , Prentki M.
Biochem. J.340:213-217(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM MITOCHONDRIAL);CATALYTIC ACTIVITY;TISSUE SPECIFICITY
2.

"Characterization of rat liver malonyl-CoA decarboxylase and the study of its role in regulating fatty acid metabolism."
Dyck J.R. , Berthiaume L.G. , Thomas P.D. , Kantor P.F. , Barr A.J. , Barr R. , Singh D. , Hopkins T.A. , Voilley N. , Prentki M. , Lopaschuk G.D.
Biochem. J.350:599-608(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM MITOCHONDRIAL);PARTIAL PROTEIN SEQUENCE;FUNCTION;PROTEOLYTIC PROCESSING;TISSUE SPECIFICITY
3.

"Rat malonyl-CoA decarboxylase; cloning, expression in E. coli and its biochemical characterization."
Lee G.Y. , Bahk Y.Y. , Kim Y.S.
J. Biochem. Mol. Biol.35:213-219(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM MITOCHONDRIAL);CATALYTIC ACTIVITY;BIOPHYSICOCHEMICAL PROPERTIES;TISSUE SPECIFICITY
strain: Sprague-Dawley.
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM MITOCHONDRIAL)
tissue: Prostate.
5.

"MCD encodes peroxisomal and cytoplasmic forms of malonyl-CoA decarboxylase and is mutated in malonyl-CoA decarboxylase deficiency."
Sacksteder K.A. , Morrell J.C. , Wanders R.J.A. , Matalon R. , Gould S.J.
J. Biol. Chem.274:24461-24468(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION (ISOFORM CYTOPLASMIC+PEROXISOMAL);TISSUE SPECIFICITY
6.

"Malonyl coenzyme a decarboxylase inhibition protects the ischemic heart by inhibiting fatty acid oxidation and stimulating glucose oxidation."
Dyck J.R. , Cheng J.F. , Stanley W.C. , Barr R. , Chandler M.P. , Brown S. , Wallace D. , Arrhenius T. , Harmon C. , Yang G. , Nadzan A.M. , Lopaschuk G.D.
Circ. Res.94:E78-E84(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
7.

"Malonyl-CoA decarboxylase is present in the cytosolic, mitochondrial and peroxisomal compartments of rat hepatocytes."
Joly E. , Bendayan M. , Roduit R. , Saha A.K. , Ruderman N.B. , Prentki M.
FEBS Lett.579:6581-6586(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CATALYTIC ACTIVITY;SUBCELLULAR LOCATION
8.

"Mass spectrometric identification of K210 essential for rat malonyl-CoA decarboxylase catalysis."
Nam H.W. , Lee G.Y. , Kim Y.S.
J. Proteome Res.5:1398-1406(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION AT LYS-58; LYS-167; LYS-210; LYS-316; LYS-388 AND LYS-441;MUTAGENESIS OF LYS-210; LYS-308 AND LYS-388

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