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Index > Protein center > ENPP3(Gene name) > Human
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  • ENPP3 (Gene name),
  • Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (Protein name ),  ENPP3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    ENPP3(PDNP3);
    Protein name:
    Ectonucleotide pyrophosphatase/phosphodiesterase family member 3(E-NPP 3);
    Alternative:
    Phosphodiesterase I/nucleotide pyrophosphatase 3;Phosphodiesterase I beta(PD-Ibeta);
    CD:
    CD203c;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Cleaves a variety of phosphodiester and phosphosulfate bonds including deoxynucleotides, nucleotide sugars, and NAD.
    Subcellular Location:
    Membrane Single-pass type II membrane protein Secreted Located to the apical surface in intestinal and kidney epithelial cells. Located to the cell surface of basophils, and to the apical plasma membrane of bile duct cells. Secreted in serum, and in lumen of epithelial cells.
    Protein Attributes:
    Sequence length:
    875
    Sequence:
    50:
    MESTLTLATE | QPVKKNTLKK | YKIACIVLLA | LLVIMSLGLG | LGLGLRKLEK | 
    100:
    QGSCRKKCFD | ASFRGLENCR | CDVACKDRGD | CCWDFEDTCV | ESTRIWMCNK | 
    150:
    FRCGETRLEA | SLCSCSDDCL | QRKDCCADYK | SVCQGETSWL | EENCDTAQQS | 
    200:
    QCPEGFDLPP | VILFSMDGFR | AEYLYTWDTL | MPNINKLKTC | GIHSKYMRAM | 
    250:
    YPTKTFPNHY | TIVTGLYPES | HGIIDNNMYD | VNLNKNFSLS | SKEQNNPAWW | 
    300:
    HGQPMWLTAM | YQGLKAATYF | WPGSEVAING | SFPSIYMPYN | GSVPFEERIS | 
    350:
    TLLKWLDLPK | AERPRFYTMY | FEEPDSSGHA | GGPVSARVIK | ALQVVDHAFG | 
    400:
    MLMEGLKQRN | LHNCVNIILL | ADHGMDQTYC | NKMEYMTDYF | PRINFFYMYE | 
    450:
    GPAPRIRAHN | IPHDFFSFNS | EEIVRNLSCR | KPDQHFKPYL | TPDLPKRLHY | 
    500:
    AKNVRIDKVH | LFVDQQWLAV | RSKSNTNCGG | GNHGYNNEFR | SMEAIFLAHG | 
    550:
    PSFKEKTEVE | PFENIEVYNL | MCDLLRIQPA | PNNGTHGSLN | HLLKVPFYEP | 
    600:
    SHAEEVSKFS | VCGFANPLPT | ESLDCFCPHL | QNSTQLEQVN | QMLNLTQEEI | 
    650:
    TATVKVNLPF | GRPRVLQKNV | DHCLLYHREY | VSGFGKAMRM | PMWSSYTVPQ | 
    700:
    LGDTSPLPPT | VPDCLRADVR | VPPSESQKCS | FYLADKNITH | GFLYPPASNR | 
    750:
    TSDSQYDALI | TSNLVPMYEE | FRKMWDYFHS | VLLIKHATER | NGVNVVSGPI | 
    800:
    FDYNYDGHFD | APDEITKHLA | NTDVPIPTHY | FVVLTSCKNK | SHTPENCPGW | 
    850:
    LDVLPFIIPH | RPTNVESCPE | GKPEALWVEE | RFTAHIARVR | DVELLTGLDF | 
    875:
    YQDKVQPVSE | ILQLKTYLPT | FETTI
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    MIM:
    Pfam:
    UniGene:
    KEGG:
    SMR:
    Uniprot:
     
    FOR
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    CLIA Kit for Human E-NPP 3
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human E-NPP 3
    Cat.:
    U11643m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human E-NPP 3
    Cat.:
    U11643r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human E-NPP 3
    Cat.:
    U11643b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human E-NPP 3
    Polyclonal Antibody for Human E-NPP 3
    Cat.:
    P11643Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human E-NPP 3
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    Packing:
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    Polyclonal Antibody for Human E-NPP 3
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    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human E-NPP 3
    Monoclonal Antibody for Human E-NPP 3
    Monoclonal Antibody for Human E-NPP 3
    Monoclonal Antibody for Human E-NPP 3
    Protein for Human E-NPP 3
    Protein for Human E-NPP 3
    Protein for Human E-NPP 3
    Protein for Human E-NPP 3

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    References
    1. 1.
      "Molecular cloning and chromosomal localization of PD-Ibeta (PDNP3), a new member of the human phosphodiesterase I genes."
      Piao J.-H. , Goding J.W. , Nakamura H. , Sano K.
      Genomics45:412-415(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
      tissue: Prostate.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Endometrium.
    3. 3.
      "The DNA sequence and analysis of human chromosome 6."
      Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
      Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The basophil activation marker defined by antibody 97A6 is identical to the ectonucleotide pyrophosphatase/phosphodiesterase 3."
      Buehring H.J. , Seiffert M. , Giesert C. , Marxer A. , Kanz L. , Valent P. , Sano K.
      Blood97:3303-3305(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 393-405;IDENTIFICATION AS CD203C;SUBCELLULAR LOCATION
    6. 6.
      "Expression and localization of ecto-nucleotide pyrophosphatase/phosphodiesterase I-1 (E-NPP1/PC-1) and -3 (E-NPP3/CD203c/PD-Ibeta/B10/gp130(RB13-6)) in inflammatory and neoplastic bile duct diseases."
      Yano Y. , Hayashi Y. , Sano K. , Nagano H. , Nakaji M. , Seo Y. , Ninomiya T. , Yoon S. , Yokozaki H. , Kasuga M.
      Cancer Lett.207:139-147(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    7. 7.
      "The basophil-specific ectoenzyme E-NPP3 (CD203c) as a marker for cell activation and allergy diagnosis."
      Buehring H.J. , Streble A. , Valent P.
      Int. Arch. Allergy Immunol.133:317-329(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION;POSSIBLE APPLICATION IN ALLERGY DIAGNOSIS
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