Gene name:
    Gdf5 (Bp;Gdf-5) ;
    
 
    Protein name:
    Growth/differentiation factor 5 (GDF-5) ;
    
    Alternative:
    
    
    
 
    Organism:
        
        
        
        
        
        
    
        Mouse  (Mus musculus).  
    
 
General Annotation
    Sub Unit:
    Homodimer; disulfide-linked.
    
 
    Function:
    Could be involved in bone and cartilage formation. Chondrogenic signaling is mediated by the high-affinity receptor BMPR1B.
    
 
    
        
        Subcellular Location:
        
    
     
     
      Secreted 
     
  
    
 
    
    Protein Attributes:
    
    50:
    MRLPKLLTLL |  LWHLAWLDLE |  LICTVLGAPD |  LGQRTPGAKP |  GLTKAEAKER |  
    
 
    100:
    PPLARNVFRP |  GGHIYGVGAT |  NARAKGSSGQ |  TQAKKDEPRK |  MPPRSGGPET |  
    
 
    150:
    KPGPSSQTRQ |  AAARTVTPKG |  QLPGGKASSK |  AGSAPSSFLL |  KKTREPGTPR |  
    
 
    200:
    EPKEPFRPPP |  ITPHEYMLSL |  YRTLSDADRK |  GGNSSVKLEA |  GLANTITSFI |  
    
 
    250:
    DKGQDDRGPA |  VRKQRYVFDI |  SALEKDGLLG |  AELRILRKKP |  LDVAKPAVPS |  
    
 
    300:
    SGRVAQLKLS |  SCPSGRQPAA |  LLDVRSVPGL |  DGSGWEVFDI |  WKLFRNFKNS |  
    
 
    350:
    AQLCLELEAW |  ERGRAVDLRG |  LGFERTARQV |  HEKALFLVFG |  RTKKRDLFFN |  
    
 
    400:
    EIKARSGQDD |  KTVYEYLFSQ |  RRKRRAPLAN |  RQGKRPSKNL |  KARCSRKALH |  
    
 
    450:
    VNFKDMGWDD |  WIIAPLEYEA |  FHCEGLCEFP |  LRSHLEPTNH |  AVIQTLMNSM |  
    
 
    495:
    DPESTPPTCC |  VPTRLSPISI |  LFIDSANNVV |  YKQYEDMVVE |  SCGCR
    
 
      Vaild Sequence:
    
 
Related Databases
Uniprot:
 
 
    
        
        ELISA Kit
         
        
        CLIA Kit
         
        
        Polyclonal Antibody
         
        
        Monoclonal Antibody
         
        
        Protein
         
        
     
FOR
    
        
        Mouse
         
        
        Human
         
        
     
    
        ELISA Kit for Mouse GDF-5
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
    
    
    
    
 
    
        ELISA Kit for Mouse GDF-5
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Mouse GDF-5
        
     
    
    
    
    
   
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Mouse GDF-5
        
     
    
    
    
    
   
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Mouse GDF-5
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Mouse GDF-5
        
     
    
    
    
    
    
    
 
 
 
 
 
 
 
 
    R&D Technical Data
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
 
    Precision
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
 
    Recovery
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
 
    Linearity
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
 
    
    
    References
    
    
        
            
        
            
                1.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [MRNA];VARIANT SER-98 
                    
                    
                    strain :
                    
CD-1 . tissue :
                    
Embryo .  
             
         
            
        
            
                2.
                
                    
                        
                            "Lineage-specific biology revealed by a finished genome assembly of the mouse." 
                        
                        
                            Church D.M. 
                        ,
                            
Goodstadt L. 
                        ,
                            
Hillier L.W. 
                        ,
                            
Zody M.C. 
                        ,
                            
Goldstein S. 
                        ,
                            
She X. 
                        ,
                            
Bult C.J. 
                        ,
                            
Agarwala R. 
                        ,
                            
Cherry J.L. 
                        ,
                            
DiCuccio M. 
                        ,
                            
Hlavina W. 
                        ,
                            
Kapustin Y. 
                        ,
                            
Meric P. 
                        ,
                            
Maglott D. 
                        ,
                            
Birtle Z. 
                        ,
                            
Marques A.C. 
                        ,
                            
Graves T. 
                        ,
                            
Zhou S. 
                        ,
                        
                        
                            Teague B. 
                        ,
                            Potamousis K. 
                        ,
                            Churas C. 
                        ,
                            Place M. 
                        ,
                            Herschleb J. 
                        ,
                            Runnheim R. 
                        ,
                            Forrest D. 
                        ,
                            Amos-Landgraf J. 
                        ,
                            Schwartz D.C. 
                        ,
                            Cheng Z. 
                        ,
                            Lindblad-Toh K. 
                        ,
                            Eichler E.E. 
                        ,
                            Ponting C.P. 
                        
                             
                              more...   
                             
                        
                        
                        
                            PLoS Biol.7:E1000112-E1000112(2009)
                         
                        
                        
                        [
PubMed ]
                        [
Europe PMC ]
                        [
Abstract ]
                        
                    
 
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] 
                    
                    
                    strain :
                    
C57BL/6J .  
             
         
            
        
            
                3.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] 
                    
                    
                 
             
         
            
        
            
                4.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT SER-98 
                    
                    
                    strain :
                    
FVB/N . tissue :
                    
Salivary gland .  
             
         
            
        
            
                5.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for INTERACTION WITH HTRA3 
                    
                    
                 
             
         
            
        
            
                6.
                
                    
                        
                            "HtrA1 serine protease inhibits signaling mediated by Tgfbeta family proteins." 
                        
                        
                            Oka C. 
                        ,
                            
Tsujimoto R. 
                        ,
                            
Kajikawa M. 
                        ,
                            
Koshiba-Takeuchi K. 
                        ,
                            
Ina J. 
                        ,
                            
Yano M. 
                        ,
                            
Tsuchiya A. 
                        ,
                            
Ueta Y. 
                        ,
                            
Soma A. 
                        ,
                            
Kanda H. 
                        ,
                            
Matsumoto M. 
                        ,
                            
Kawaichi M. 
                        
                        
                        
                        
                            Development131:1041-1053(2004)
                         
                        
                        
                        [
PubMed ]
                        [
Europe PMC ]
                        [
Abstract ]
                        
                    
 
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for INTERACTION WITH HTRA1 
                    
                    
                 
             
         
            
        
            
                7.
                
                    
                        
                            "BMP signaling controls muscle mass." 
                        
                        
                            Sartori R. 
                        ,
                            
Schirwis E. 
                        ,
                            
Blaauw B. 
                        ,
                            
Bortolanza S. 
                        ,
                            
Zhao J. 
                        ,
                            
Enzo E. 
                        ,
                            
Stantzou A. 
                        ,
                            
Mouisel E. 
                        ,
                            
Toniolo L. 
                        ,
                            
Ferry A. 
                        ,
                            
Stricker S. 
                        ,
                            
Goldberg A.L. 
                        ,
                            
Dupont S. 
                        ,
                            
Piccolo S. 
                        ,
                            
Amthor H. 
                        ,
                            
Sandri M. 
                        
                        
                        
                        
                            Nat. Genet.45:1309-1318(2013)
                         
                        
                        
                        [
PubMed ]
                        [
Europe PMC ]
                        [
Abstract ]
                        
                    
 
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for FUNCTION;INDUCTION