Ifnar2 Polyclonal Antibody for Mouse(Mus musculus) | EIAab.comIfnar2 Polyclonal Antibody for Mouse(Mus musculus)

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Ifnar2 (Gene name),

Interferon alpha/beta receptor 2 (Protein name ), INAR2_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Ifnar2;

Protein name:

Interferon alpha/beta receptor 2(IFN-R-2;IFN-alpha/beta receptor 2);

Alternative:

Type I interferon receptor 2;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Heterodimer with IFNAR1; in presence of interferon alpha and/or beta ligands forms the type I interferon receptor. Isoform 1 interacts with the transcriptional factors STAT1 and STAT2. Interacts with JAK1.

Function:

Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 2 and 3 may be potent inhibitors of type I IFN receptor activity.

Subcellular Location:

Isoform 3 Secreted

Protein Attributes:

Sequence length:

513

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

513:

DSDADVGDGY | IMR

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

O35664

KEGG:

mmu:15976

String:

O35664

UniGene:

Mm.6834

Pfam:

PF09294

Uniprot:

O35664

FOR

ELISA Kit for Mouse IFN-R-2

Cat.:

E1101h

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Packing:

96T

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ELISA Kit for Mouse IFN-R-2

Cat.:

E1101m

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96T

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ELISA Kit for Mouse IFN-R-2

Cat.:

E1101b

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MSDS:

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Packing:

96T

CLIA Kit for Mouse IFN-R-2

Cat.:

U1101m

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MSDS:

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Packing:

96T

CLIA Kit for Mouse IFN-R-2

Cat.:

U1101b

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MSDS:

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Packing:

96T

CLIA Kit for Mouse IFN-R-2

Cat.:

U1101h

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Manual:

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MSDS:

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Packing:

96T

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Polyclonal Antibody for Mouse IFN-R-2

Cat.:

P1101Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse IFN-R-2

Cat.:

P1101Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse IFN-R-2

Protein for Mouse IFN-R-2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Mammalian type I interferon receptors consists of two subunits: IFNaR1 and IFNaR2."
Kim S.H. , Cohen B. , Novick D. , Rubinstein M.
Gene196:279-286(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2 AND 3);ALTERNATIVE SPLICING;TISSUE SPECIFICITY
strain: C57BL/6.
tissue: Brain.
2.

"Cloning and characterization of soluble and transmembrane isoforms of a novel component of the murine type I interferon receptor, IFNAR 2."
Owczarek C.M. , Hwang S.Y. , Holland K.A. , Gulluyan L.M. , Tavaria M. , Weaver B. , Reich N.C. , Kola I. , Hertzog P.J.
J. Biol. Chem.272:23865-23870(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 3);TISSUE SPECIFICITY
tissue: Lung.
tissue: Testis.
3.

"Multiple regions within the promoter of the murine Ifnar-2 gene confer basal and inducible expression."
Hardy M.P. , Hertzog P.J. , Owczarek C.M.
Biochem. J.365:355-367(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
strain: 129/SvJ.
4.

"The transcriptional landscape of the mammalian genome."
Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain: C57BL/6J.
tissue: Bone marrow.
tissue: Cerebellum.
5.

Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: FVB/N.
tissue: Salivary gland.
7.

"Proteome-wide characterization of N-glycosylation events by diagonal chromatography."
Ghesquiere B. , Van Damme J. , Martens L. , Vandekerckhove J. , Gevaert K.
J. Proteome Res.5:2438-2447(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-195
strain: C57BL/6.
tissue: Plasma.
8.

"The phagosomal proteome in interferon-gamma-activated macrophages."
Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-448 AND SER-465;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]

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