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Index > Protein center > LFNG(Gene name) > Human
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  • LFNG (Gene name),
  • Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (Protein name ),  LFNG_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    LFNG;
    Protein name:
    Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe;
    Alternative:
    O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Decreases the binding of JAGGED1 to NOTCH2 but not that of DELTA1. Essential mediator of somite segmentation and patterning.
    Subcellular Location:
    Golgi apparatus membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    379
    Sequence:
    50:
    MLKRCGRRLL | LALAGALLAC | LLVLTADPPP | PPLPAERGRR | ALRSLAGPAG | 
    100:
    AAPAPGLGAA | AAAPGALVRD | VHSLSEYFSL | LTRARRDAGP | PPGAAPRPAD | 
    150:
    GHPRPLAEPL | APRDVFIAVK | TTKKFHRARL | DLLLETWISR | HKEMTFIFTD | 
    200:
    GEDEALARHT | GNVVITNCSA | AHSRQALSCK | MAVEYDRFIE | SGRKWFCHVD | 
    250:
    DDNYVNLRAL | LRLLASYPHT | RDVYVGKPSL | DRPIQAMERV | SENKVRPVHF | 
    300:
    WFATGGAGFC | ISRGLALKMS | PWASGGHFMN | TAERIRLPDD | CTIGYIVEAL | 
    350:
    LGVPLIRSGL | FHSHLENLQQ | VPTSELHEQV | TLSYGMFENK | RNAVHVKGPF | 
    379:
    SVEADPSRFR | SIHCHLYPDT | PWCPRTAIF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    UniGene:
    Pfam:
    MIM:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
    Cat.:
    E15413h
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    96T
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    ELISA Kit for Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
    Cat.:
    E15413r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
    Cat.:
    E15413m
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    Packing:
    96T
    ELISA Kit for Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
    Cat.:
    E15413c
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    Packing:
    96T
    ELISA Kit for Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
    Cat.:
    E15413b
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    Packing:
    96T
    CLIA Kit for Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
    Cat.:
    U15413c
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
    Cat.:
    U15413r
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
    Cat.:
    U15413m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
    Cat.:
    U15413h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
    Cat.:
    U15413b
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
    Polyclonal Antibody for Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
    Polyclonal Antibody for Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
    Cat.:
    P15413Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
    Cat.:
    P15413Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
    Cat.:
    P15413Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
    Monoclonal Antibody for Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
    Monoclonal Antibody for Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
    Monoclonal Antibody for Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
    Monoclonal Antibody for Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
    Protein for Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
    Protein for Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
    Protein for Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
    Protein for Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
    Protein for Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4)
    2. 2.
      "The DNA sequence of human chromosome 7."
      Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , more...
      Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway."
      Johnston S.H. , Rauskolb C. , Wilson R. , Prabhakaran B. , Irvine K.D. , Vogt T.F.
      Development124:2245-2254(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 105-361 (ISOFORM 3)
    4. 4.
      "Clock regulatory elements control cyclic expression of Lunatic fringe during somitogenesis."
      Cole S.E. , Levorse J.M. , Tilghman S.M. , Vogt T.F.
      Dev. Cell3:75-84(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-144 (ISOFORM 1)
    5. 5.
      "Homo sapiens fringe gene homolog."
      Holloway J. , Blumberg H. , Jelinek L. , Whitmore T. , Jaspers S. , Gross J. , Haldeman B. , Taft D. , O'Hara P.
      Submitted (1999-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 104-361 (ISOFORM 3)
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Kidney.
    7. 7.
      "Manic fringe and lunatic fringe modify different sites of the Notch2 extracellular region, resulting in different signaling modulation."
      Shimizu K. , Chiba S. , Saito T. , Kumano K. , Takahashi T. , Hirai H.
      J. Biol. Chem.276:25753-25758(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
    8. 8.
      "Mutation of the LUNATIC FRINGE gene in humans causes spondylocostal dysostosis with a severe vertebral phenotype."
      Sparrow D.B. , Chapman G. , Wouters M.A. , Whittock N.V. , Ellard S. , Fatkin D. , Turnpenny P.D. , Kusumi K. , Sillence D. , Dunwoodie S.L.
      Am. J. Hum. Genet.78:28-37(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT SCDO3 LEU-188;CHARACTERIZATION OF VARIANT SCDO3 LEU-188
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ARG-38 AND MET-346
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