LILRA2 Polyclonal Antibody for Human(Homo sapiens) | EIAab.comLILRA2 Polyclonal Antibody for Human(Homo sapiens)

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LILRA2 (Gene name),

Leukocyte immunoglobulin-like receptor subfamily A member 2 (Protein name ), LIRA2_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

LILRA2(ILT1;LIR7);

Protein name:

Leukocyte immunoglobulin-like receptor subfamily A member 2;

Alternative:

Immunoglobulin-like transcript 1(ILT-1);CD85 antigen-like family member H;Leukocyte immunoglobulin-like receptor 7(LIR-7);

CD:

CD85h;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homodimer.

Function:

Does not bind class I MHC antigens.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

483

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

483:

IRMGVAGLVL | VVLGILLFEA | QHSQRSLQDA | AGR

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.655593

SMR:

Q8N149

KEGG:

hsa:11027

MIM:

604812

STRING:

9606.ENSP00000251377

String:

Q8N149

Uniprot:

Q8N149

FOR

ELISA Kit for Human Leukocyte immunoglobulin-like receptor subfamily A member 2

Cat.:

E9191h

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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CLIA Kit for Human Leukocyte immunoglobulin-like receptor subfamily A member 2

Cat.:

U9191h

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Leukocyte immunoglobulin-like receptor subfamily A member 2

Cat.:

P9191Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Leukocyte immunoglobulin-like receptor subfamily A member 2

Protein for Human Leukocyte immunoglobulin-like receptor subfamily A member 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Intra-Assay CV: ≤8.6%

Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

Inter-Assay CV: ≤11.4%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

Recovery was determined by spiking various levels of LIRA2 into serum and plasma .

Sample Type	Average(%)	Recovery Range(%)
Serum	104	97-106
Plasma	102	95-106

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

The linearity of the kit was assayed by testing samples spiked with appropriate concentration of LIRA2 and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample	1：2	1:4	1:8	1:16
serum(n=5)	97-111%	99-109%	98-110%	100-107%
EDTA plasma(n=5)	95-109%	96-107%	97-108%	98-106%
heparin plasma(n=5)	93-110%	94-110%	99-106%	96-109%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules."
Borges L. , Hsu M.-L. , Fanger N. , Kubin M. , Cosman D.
J. Immunol.159:5192-5196(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY
tissue: Peripheral blood leukocyte.
2.

"Alternative mRNA splicing creates transcripts encoding soluble proteins from most LILR genes."
Jones D.C. , Roghanian A. , Brown D.P. , Chang C. , Allen R.L. , Trowsdale J. , Young N.T.
Eur. J. Immunol.39:3195-3206(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 3 AND 4);SUBCELLULAR LOCATION (ISOFORM 4);ALTERNATIVE SPLICING
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue: Lung.
tissue: Pancreas.
4.

"Crystal structure of myeloid cell activating receptor leukocyte Ig-like receptor A2 (LILRA2/ILT1/LIR-7) domain swapped dimer: molecular basis for its non-binding to MHC complexes."
Chen Y. , Gao F. , Chu F. , Peng H. , Zong L. , Liu Y. , Tien P. , Gao G.F.
J. Mol. Biol.386:841-853(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS) OF 24-219;FUNCTION;SUBUNIT;DISULFIDE BONDS

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