LRP4 Polyclonal Antibody for Human(Homo sapiens) | EIAab.comLRP4 Polyclonal Antibody for Human(Homo sapiens)

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Index > Protein center > LRP4(Gene name) > Human

LRP4 (Gene name),

Low-density lipoprotein receptor-related protein 4 (Protein name ), LRP4_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

LRP4(KIAA0816;LRP10;MEGF7);

Protein name:

Low-density lipoprotein receptor-related protein 4(LRP-4);

Alternative:

Multiple epidermal growth factor-like domains 7;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Potential cell surface endocytic receptor, which binds and internalizes extracellular ligands for degradation by lysosomes. Involved in the negative regulation of the canonical Wnt signaling pathway, being able to antagonize the LRP6-mediated activation of this pathway.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

1905

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SESQV

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

O75096

STRING:

9606.ENSP00000367888

UniGene:

Hs.4930

Pfam:

PF12662

KEGG:

hsa:4038

SMR:

O75096

MIM:

212780

Pfam:

PF00057

Uniprot:

O75096

FOR

ELISA Kit for Human LRP-4

Cat.:

E1102h

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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ELISA Kit for Human LRP-4

Cat.:

E1102r

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Human LRP-4

Cat.:

E1102m

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MSDS:

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Packing:

96T

CLIA Kit for Human LRP-4

Cat.:

U1102r

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MSDS:

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Packing:

96T

CLIA Kit for Human LRP-4

Cat.:

U1102h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Human LRP-4

Cat.:

U1102m

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human LRP-4

Cat.:

P1102Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human LRP-4

Cat.:

P1102Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human LRP-4

Cat.:

P1102Rb-r

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human LRP-4

Protein for Human LRP-4

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Low density lipoprotein receptor-related protein 10."
Ishikawa K. , Fujimoto H. , Kim D. , Saeki S.
Submitted (2002-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANTS VAL-1086; GLY-1554 AND GLN-1646
tissue: Brain.
2.

"Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening."
Nakayama M. , Nakajima D. , Nagase T. , Nomura N. , Seki N. , Ohara O.
Genomics51:27-34(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANTS VAL-1086; GLY-1554 AND GLN-1646
tissue: Brain.
3.

"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Taylor T.D. , Noguchi H. , Totoki Y. , Toyoda A. , Kuroki Y. , Dewar K. , Lloyd C. , Itoh T. , Takeda T. , Kim D.-W. , She X. , Barlow K.F. , Bloom T. , Bruford E. , Chang J.L. , Cuomo C.A. , Eichler E. , FitzGerald M.G. , more...
Nature440:497-500(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANTS VAL-1086; GLY-1554 AND GLN-1646
tissue: Muscle.
5.

"LRP4 mutations alter Wnt/beta-catenin signaling and cause limb and kidney malformations in Cenani-Lenz syndrome."
Li Y. , Pawlik B. , Elcioglu N. , Aglan M. , Kayserili H. , Yigit G. , Percin F. , Goodman F. , Nurnberg G. , Cenani A. , Urquhart J. , Chung B.D. , Ismail S. , Amr K. , Aslanger A.D. , Becker C. , Netzer C. , Scambler P. , more...
Am. J. Hum. Genet.86:696-706(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN THE REGULATION OF CANONICAL WTN SIGNALING;VARIANTS CLSS ASN-137; TYR-160; ASN-449; PRO-461; PHE-473; ASN-529 AND ARG-1017;CHARACTERIZATION OF VARIANTS CLSS ASN-137; TYR-160; ASN-449; PHE-473 AND ASN-529
6.

"Bone overgrowth-associated mutations in the LRP4 gene impair sclerostin facilitator function."
Leupin O. , Piters E. , Halleux C. , Hu S. , Kramer I. , Morvan F. , Bouwmeester T. , Schirle M. , Bueno-Lozano M. , Fuentes F.J. , Itin P.H. , Boudin E. , de Freitas F. , Jennes K. , Brannetti B. , Charara N. , Ebersbach H. , Geisse S. , more...
J. Biol. Chem.286:19489-19500(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH SOST;TISSUE SPECIFICITY;VARIANTS SOST2 TRP-1170 AND SER-1186;CHARACTERIZATION OF VARIANTS SOST2 TRP-1170 AND SER-1186;IDENTIFICATION BY MASS SPECTROMETRY

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