Masp2 Polyclonal Antibody for Rat(Rattus norvegicus) | EIAab.comMasp2 Polyclonal Antibody for Rat(Rattus norvegicus)

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Index > Protein center > Masp2(Gene name) > Rat

Masp2 (Gene name),

Mannan-binding lectin serine protease 2 (Protein name ), MASP2_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Masp2;

Protein name:

Mannan-binding lectin serine protease 2;

Alternative:

Mannose-binding protein-associated serine protease 2(MASP-2);MBL-associated serine protease 2;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Homodimer; disulfide-linked. Binds MBL2. Isoform 2 binds to MASP1. Binds SERPING1.

Function:

Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

685

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

685:

IVSWGSINCG | GSEQYGVYTK | VTNYIPWIEN | IINNF

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q9JJS8

SMR:

Q9JJS8

Pfam:

PF00431

UniGene:

Rn.45144

KEGG:

rno:64459

Uniprot:

Q9JJS8

FOR

ELISA Kit for Rat Mannan-binding lectin serine protease 2

Cat.:

E2234h

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96T

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ELISA Kit for Rat Mannan-binding lectin serine protease 2

Cat.:

E2234m

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96T

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ELISA Kit for Rat Mannan-binding lectin serine protease 2

Cat.:

E2234r

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96T

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CLIA Kit for Rat Mannan-binding lectin serine protease 2

Cat.:

U2234h

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96T

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CLIA Kit for Rat Mannan-binding lectin serine protease 2

Cat.:

U2234m

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MSDS:

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Packing:

96T

CLIA Kit for Rat Mannan-binding lectin serine protease 2

Cat.:

U2234r

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat Mannan-binding lectin serine protease 2

Cat.:

P2234Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Mannan-binding lectin serine protease 2

Cat.:

P2234Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Mannan-binding lectin serine protease 2

Cat.:

P2234Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat Mannan-binding lectin serine protease 2

Protein for Rat Mannan-binding lectin serine protease 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The rat and mouse homologues of MASP-2 and MAp19, components of the mannan-binding lectin activation pathway of complement."
Stover C.M. , Thiel S. , Lynch N.J. , Schwaeble W.J.
J. Immunol.163:6848-6859(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);SUBUNIT STRUCTURE;ACTIVATION BY PROTEOLYTIC CLEAVAGE;TISSUE SPECIFICITY
strain: Fischer 344.
2.

"Organization of the MASP2 locus and its expression profile in mouse and rat."
Stover C.M. , Lynch N.J. , Hanson S.J. , Windbichler M. , Gregory S.G. , Schwaeble W.J.
Mamm. Genome15:887-900(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"Interaction of mannose-binding protein with associated serine proteases: effects of naturally occurring mutations."
Wallis R. , Dodd R.B.
J. Biol. Chem.275:30962-30969(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 8-685 (ISOFORM 1);PROTEIN SEQUENCE OF N-TERMINUS;SUBUNIT STRUCTURE;GLYCOSYLATION;IDENTIFICATION BY MASS SPECTROMETRY;INTERACTION WITH MBL2
tissue: Liver.
4.

"Two constituents of the initiation complex of the mannan-binding lectin activation pathway of complement are encoded by a single structural gene."
Stover C.M. , Thiel S. , Thelen M. , Lynch N.J. , Vorup-Jensen T. , Jensenius J.C. , Schwaeble W.J.
J. Immunol.162:3481-3490(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 87-294 (ISOFORM 1)
tissue: Liver.
5.

"Crystal structure of the CUB1-EGF-CUB2 region of mannose-binding protein associated serine protease-2."
Feinberg H. , Uitdehaag J.C.M. , Davies J.M. , Wallis R. , Drickamer K. , Weis W.I.
EMBO J.22:2348-2359(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS) OF 20-299;HYDROXYLATION AT ASN-158;DISULFIDE BONDS;GLYCOSYLATION AT ASN-103

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