MYOF Polyclonal Antibody for Human(Homo sapiens) | EIAab.comMYOF Polyclonal Antibody for Human(Homo sapiens)

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Index > Protein center > MYOF(Gene name) > Human

MYOF (Gene name),

Myoferlin (Protein name ), MYOF_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

MYOF(FER1L3;KIAA1207);

Protein name:

Myoferlin;

Alternative:

Fer-1-like protein 3;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with DNM2 and KDR (By similarity). Interacts with EHD2; the interaction is direct.

Function:

Calcium/phospholipid-binding protein that plays a role in the plasmalemma repair mechanism of endothelial cells that permits rapid resealing of membranes disrupted by mechanical stress. Involved in endocytic recycling. Implicated in VEGF signal transduction by regulating the levels of the receptor KDR.

Subcellular Location:

Cell membrane Single-pass type II membrane protein Nucleus membrane Single-pass type II membrane protein Cytoplasmic vesicle membrane Single-pass type II membrane protein Concentrated at the membrane sites of both myoblast-myoblast and myoblast-myotube fusions. Detected at the plasmalemma in endothelial cells lining intact blood vessels (By similarity). Found at nuclear and plasma membranes. Enriched in undifferentiated myoblasts near the plasma membrane in puncate structures.

Protein Attributes:

Sequence length:

2061

Sequence:

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2050:

2061:

YLSMKIVKPN | V

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q9NZM1

String:

Q9NZM1

UniGene:

Hs.602086

MIM:

604603

Pfam:

PF00168

KEGG:

hsa:26509

Uniprot:

Q9NZM1

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ELISA Kit for Human Myoferlin

Cat.:

E2725m

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Human Myoferlin

Cat.:

E2725h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Human Myoferlin

Cat.:

U2725h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Human Myoferlin

Cat.:

U2725m

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Myoferlin

Cat.:

P2725Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Myoferlin

Cat.:

P2725Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Myoferlin

Protein for Human Myoferlin

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Myoferlin, a candidate gene and potential modifier of muscular dystrophy."
Davis D.B. , Delmonte A.J. , Ly C.T. , McNally E.M.
Hum. Mol. Genet.9:217-226(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
tissue: Heart.
tissue: Lung.
2.

"The third human FER-1-like protein is highly similar to dysferlin."
Britton S. , Freeman T. , Vafiadaki E. , Keers S. , Harrison R. , Bushby K.M.D. , Bashir R.
Genomics68:313-321(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 6);ALTERNATIVE SPLICING
tissue: Placenta.
3.

"Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
Nagase T. , Ishikawa K. , Kikuno R. , Hirosawa M. , Nomura N. , Ohara O.
DNA Res.6:337-345(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Brain.
4.

"Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
Nakajima D. , Okazaki N. , Yamakawa H. , Kikuno R. , Ohara O. , Nagase T.
DNA Res.9:99-106(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
5.

"The DNA sequence and comparative analysis of human chromosome 10."
Deloukas P. , Earthrowl M.E. , Grafham D.V. , Rubenfield M. , French L. , Steward C.A. , Sims S.K. , Jones M.C. , Searle S. , Scott C. , Howe K. , Hunt S.E. , Andrews T.D. , Gilbert J.G.R. , Swarbreck D. , Ashurst J.L. , Taylor A. , Battles J. , more...
Nature429:375-381(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 5 AND 8)
tissue: Lung.
7.

"The full-ORF clone resource of the German cDNA consortium."
Bechtel S. , Rosenfelder H. , Duda A. , Schmidt C.P. , Ernst U. , Wellenreuther R. , Mehrle A. , Schuster C. , Bahr A. , Bloecker H. , Heubner D. , Hoerlein A. , Michel G. , Wedler H. , Koehrer K. , Ottenwaelder B. , Poustka A. , Wiemann S. , more...
BMC Genomics8:399-399(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 621-2061 (ISOFORM 3)
tissue: Fetal brain.
8.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1389-2061 (ISOFORMS 1/2)
tissue: Thyroid.
9.

"Calcium-sensitive phospholipid binding properties of normal and mutant ferlin C2 domains."
Davis D.B. , Doherty K.R. , Delmonte A.J. , McNally E.M.
J. Biol. Chem.277:22883-22888(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY
10.

"Myoferlin regulates vascular endothelial growth factor receptor-2 stability and function."
Bernatchez P.N. , Acevedo L. , Fernandez-Hernando C. , Murata T. , Chalouni C. , Kim J. , Erdjument-Bromage H. , Shah V. , Gratton J.-P. , McNally E.M. , Tempst P. , Sessa W.C.
J. Biol. Chem.282:30745-30753(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
11.

"The endocytic recycling protein EHD2 interacts with myoferlin to regulate myoblast fusion."
Doherty K.R. , Demonbreun A.R. , Wallace G.Q. , Cave A. , Posey A.D. , Heretis K. , Pytel P. , McNally E.M.
J. Biol. Chem.283:20252-20260(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH EHD2;MUTAGENESIS OF 238-ASN--PHE-240;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;IDENTIFICATION BY MASS SPECTROMETRY
12.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-174;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
13.

"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-884;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
14.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1915;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
15.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
16.

"Fam65b is important for formation of the HDAC6-dysferlin protein complex during myogenic cell differentiation."
Balasubramanian A. , Kawahara G. , Gupta V.A. , Rozkalne A. , Beauvais A. , Kunkel L.M. , Gussoni E.
FASEB J.28:2955-2969(2014) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FAM65B
17.

"The solution structure of the first C2 domain of human myoferlin."
RIKEN structural genomics initiative (RSGI)
Submitted (2006-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 1-127
18.

"Solution structure of the inner DysF domain of myoferlin and implications for limb girdle muscular dystrophy type 2b."
Patel P. , Harris R. , Geddes S.M. , Strehle E.-M. , Watson J.D. , Bashir R. , Bushby K. , Driscoll P.C. , Keep N.H.
J. Mol. Biol.379:981-990(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 923-1040

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