Protein name:
Nuclear receptor subfamily 1 group D member 1 ;
Alternative:
V-erbA-related protein 1 (EAR-1) ;Rev-erbA-alpha ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with NR2E3 (By similarity). Interacts with C1D.
Function:
Functions as a constitutive transcriptional repressor. Possible receptor for triiodothyronine.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MTTLDSNNNT | GGVITYIGSS | GSSPSRTSPE | SLYSDSSNGS | FQSLTQGCPT |
100:
YFPPSPTGSL | TQDPARSFGS | APPSLSDDSS | PSSASSSSSS | SSSSFYNGSP |
150:
PGSLQVAMED | SSRVSPSKGT | SNITKLNGMV | LLCKVCGDVA | SGFHYGVHAC |
200:
EGCKGFFRRS | IQQNIQYKRC | LKNENCSIVR | INRNRCQQCR | FKKCLSVGMS |
250:
RDAVRFGRIP | KREKQRMLAE | MQSAMNLANN | QLSSLCPLET | SPTPHPTSGS |
300:
MGPSPPPAPA | PTPLVGFSQF | PQQLTPPRSP | SPEPTMEDVI | SQVARAHREI |
350:
FTYAHDKLGT | SPGNFNANHA | SGSPSATTPH | RWESQGCPSA | PNDNNLLAAQ |
400:
RHNEALNGLR | QGPSSYPPTW | PSGPTHHSCH | QPNSNGHRLC | PTHVYSAPEG |
450:
EAPANSLRQG | NTKNVLLACP | MNMYPHGRSG | RTVQEIWEDF | SMSFTPAVRE |
500:
VVEFAKHIPG | FRDLSQHDQV | TLLKAGTFEV | LMVRFASLFN | VKDQTVMFLS |
550:
RTTYSLQELG | AMGMGDLLNA | MFDFSEKLNS | LALTEEELGL | FTAVVLVSAD |
600:
RSGMENSASV | EQLQETLLRA | LRALVLKNRP | SETSRFTKLL | LKLPDLRTLN |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
Rat
Mouse
ELISA Kit for Mouse Nuclear receptor subfamily 1 group D member 1
ELISA Kit for Mouse Nuclear receptor subfamily 1 group D member 1
ELISA Kit for Mouse Nuclear receptor subfamily 1 group D member 1
ELISA Kit for Mouse Nuclear receptor subfamily 1 group D member 1
CLIA Kit for Mouse Nuclear receptor subfamily 1 group D member 1
CLIA Kit for Mouse Nuclear receptor subfamily 1 group D member 1
CLIA Kit for Mouse Nuclear receptor subfamily 1 group D member 1
CLIA Kit for Mouse Nuclear receptor subfamily 1 group D member 1
Polyclonal Antibody for Mouse Nuclear receptor subfamily 1 group D member 1
Polyclonal Antibody for Mouse Nuclear receptor subfamily 1 group D member 1
Polyclonal Antibody for Mouse Nuclear receptor subfamily 1 group D member 1
Polyclonal Antibody for Mouse Nuclear receptor subfamily 1 group D member 1
Monoclonal Antibody for Mouse Nuclear receptor subfamily 1 group D member 1
Monoclonal Antibody for Mouse Nuclear receptor subfamily 1 group D member 1
Monoclonal Antibody for Mouse Nuclear receptor subfamily 1 group D member 1
Monoclonal Antibody for Mouse Nuclear receptor subfamily 1 group D member 1
Protein for Mouse Nuclear receptor subfamily 1 group D member 1
Protein for Mouse Nuclear receptor subfamily 1 group D member 1
Protein for Mouse Nuclear receptor subfamily 1 group D member 1
Protein for Mouse Nuclear receptor subfamily 1 group D member 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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"The transcriptional landscape of the mammalian genome."
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
strain :
DBA/2 .
strain :
NOD .
tissue :
Bone .
tissue :
Cerebellum .
2.
"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M.
,
Goodstadt L.
,
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,
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,
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Ponting C.P.
more...
PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
FVB/N .
tissue :
Mammary tumor .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1-186
strain :
BALB/c .
tissue :
Liver .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1-55
strain :
BALB/c .
tissue :
Skeletal muscle .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-40
strain :
C57BL/6N .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH C1D
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INDUCTION
9.
"Regulation of bile acid synthesis by the nuclear receptor Rev-erbalpha."
Duez H.
,
van der Veen J.N.
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Duhem C.
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Pourcet B.
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Touvier T.
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Fontaine C.
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Derudas B.
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Havinga R.
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Bloks V.W.
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Wolters H.
,
van der Sluijs F.H.
,
Vennstrom B.
,
Kuipers F.
,
Staels B.
Gastroenterology135:689-698(2008)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;TISSUE SPECIFICITY;PROTEASOMAL DEGRADATION
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;TISSUE SPECIFICITY
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION IN CIRCADIAN RHYTHMS;INTERACTION WITH PER2;DISRUPTION PHENOTYPE;MUTAGENESIS OF LYS-456
15.
"A circadian clock in hippocampus is regulated by interaction between oligophrenin-1 and Rev-erbalpha."
Valnegri P.
,
Khelfaoui M.
,
Dorseuil O.
,
Bassani S.
,
Lagneaux C.
,
Gianfelice A.
,
Benfante R.
,
Chelly J.
,
Billuart P.
,
Sala C.
,
Passafaro M.
Nat. Neurosci.14:1293-1301(2011)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH OPHN1;PROTEASOMAL DEGRADATION;TISSUE SPECIFICITY
16.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH PER2
17.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE;DISRUPTION PHENOTYPE
18.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;TISSUE SPECIFICITY
19.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
20.
"Involvement of urinary bladder Connexin43 and the circadian clock in coordination of diurnal micturition rhythm."
Negoro H.
,
Kanematsu A.
,
Doi M.
,
Suadicani S.O.
,
Matsuo M.
,
Imamura M.
,
Okinami T.
,
Nishikawa N.
,
Oura T.
,
Matsui S.
,
Seo K.
,
Tainaka M.
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Urabe S.
,
Kiyokage E.
,
Todo T.
,
Okamura H.
,
Tabata Y.
,
Ogawa O.
Nat. Commun.3:809-809(2012)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH SP1;INDUCTION
21.
"The nuclear receptor REV-ERBalpha mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines."
Gibbs J.E.
,
Blaikley J.
,
Beesley S.
,
Matthews L.
,
Simpson K.D.
,
Boyce S.H.
,
Farrow S.N.
,
Else K.J.
,
Singh D.
,
Ray D.W.
,
Loudon A.S.
Proc. Natl. Acad. Sci. U.S.A.109:582-587(2012)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
22.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY;INDUCTION
23.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH CCAR2
24.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
25.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
26.
"Rev-erb-alpha modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy."
Woldt E.
,
Sebti Y.
,
Solt L.A.
,
Duhem C.
,
Lancel S.
,
Eeckhoute J.
,
Hesselink M.K.
,
Paquet C.
,
Delhaye S.
,
Shin Y.
,
Kamenecka T.M.
,
Schaart G.
,
Lefebvre P.
,
Neviere R.
,
Burris T.P.
,
Schrauwen P.
,
Staels B.
,
Duez H.
Nat. Med.19:1039-1046(2013)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
27.
"The nuclear receptor Rev-erbalpha controls circadian thermogenic plasticity."
Gerhart-Hines Z.
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Feng D.
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Emmett M.J.
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Loro E.
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Briggs E.R.
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Bugge A.
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Hou C.
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Lazar M.A.
Nature503:410-413(2013)
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Cited for : FUNCTION;DISRUPTION PHENOTYPE
28.
"Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription."
Lam M.T.
,
Cho H.
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Lesch H.P.
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Gosselin D.
,
Heinz S.
,
Tanaka-Oishi Y.
,
Benner C.
,
Kaikkonen M.U.
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Kim A.S.
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Kosaka M.
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Lee C.Y.
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Watt A.
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Grossman T.R.
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Rosenfeld M.G.
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Evans R.M.
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Glass C.K.
Nature498:511-515(2013)
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Europe PMC ]
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Cited for : FUNCTION
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
30.
"Presence of multiple peripheral circadian oscillators in the tissues controlling voiding function in mice."
Noh J.Y.
,
Han D.H.
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Kim M.H.
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Ko I.G.
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Kim S.E.
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Park N.
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Kyoung Choe H.
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Kim K.H.
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Kim K.
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Kim C.J.
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Exp. Mol. Med.46:E81-E81(2014)
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PubMed ]
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Europe PMC ]
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Cited for : INDUCTION;TISSUE SPECIFICITY