Ppp2r4 Polyclonal Antibody for Mouse(Mus musculus) | EIAab.comPpp2r4 Polyclonal Antibody for Mouse(Mus musculus)

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Ppp2r4 (Gene name),

Serine/threonine-protein phosphatase 2A activator (Protein name ), PTPA_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

Ppp2r4(Ptpa);

Protein name:

Serine/threonine-protein phosphatase 2A activator;

Alternative:

Phosphotyrosyl phosphatase activator(PTPA);PP2A, subunit B', PR53 isoform;Serine/threonine-protein phosphatase 2A regulatory subunit B';Serine/threonine-protein phosphatase 2A regulatory subunit 4;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Associates with PP2A heterodimeric core enzyme PP2A(D), composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A) (By similarity). Interacts with PPP2CB.

Function:

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine-protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg(2+). Reversibly stimulates the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer PP2A(D) in presence of ATP and Mg(2+) (in vitro). The phosphotyrosyl phosphatase activity is dependent of an ATPase activty of the PP2A(D):PPP2R4 complex. Is involved in apoptosis; the function appears to be independent from PP2A.

Subcellular Location:

Cytoplasm Nucleus

Protein Attributes:

Sequence length:

323

Sequence:

50:

100:

150:

200:

250:

300:

323:

EKFPVIQHFK | FGSLLPIHPV | TSG

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF03095

SMR:

P58389

UniGene:

Mm.275393

String:

P58389

KEGG:

mmu:110854

Uniprot:

P58389

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ELISA Kit for Mouse Serine/threonine-protein phosphatase 2A activator

Cat.:

E10699h

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96T

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ELISA Kit for Mouse Serine/threonine-protein phosphatase 2A activator

Cat.:

E10699b

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Packing:

96T

ELISA Kit for Mouse Serine/threonine-protein phosphatase 2A activator

MSDS:

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ELISA Kit for Mouse Serine/threonine-protein phosphatase 2A activator

Cat.:

E10699m

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Packing:

96T

CLIA Kit for Mouse Serine/threonine-protein phosphatase 2A activator

Cat.:

U10699h

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Serine/threonine-protein phosphatase 2A activator

Cat.:

U10699b

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Serine/threonine-protein phosphatase 2A activator

Cat.:

U10699m

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse Serine/threonine-protein phosphatase 2A activator

MSDS:

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Polyclonal Antibody for Mouse Serine/threonine-protein phosphatase 2A activator

Cat.:

P10699Rb-m

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40ug/0.2ml

Polyclonal Antibody for Mouse Serine/threonine-protein phosphatase 2A activator

Cat.:

P10699Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Serine/threonine-protein phosphatase 2A activator

Monoclonal Antibody for Mouse Serine/threonine-protein phosphatase 2A activator

Protein for Mouse Serine/threonine-protein phosphatase 2A activator

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Characterization of the mouse homolog of the human phosphotyrosyl phosphatase activator, PTPA."
David J. , Yang X. , Hashimoto K. , Ramotar D.
Submitted (2001-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: C57BL/6.
tissue: Brain.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C3H/He.
strain: FVB/N.
tissue: Mammary gland.
tissue: Osteoblast.
3.

"A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo."
Fellner T. , Lackner D.H. , Hombauer H. , Piribauer P. , Mudrak I. , Zaragoza K. , Juno C. , Ogris E.
Genes Dev.17:2138-2150(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH PPP2CB

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