Ptprc Polyclonal Antibody for Rat(Rattus norvegicus) | EIAab.comPtprc Polyclonal Antibody for Rat(Rattus norvegicus)

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Ptprc (Gene name),

Receptor-type tyrosine-protein phosphatase C (Protein name ), PTPRC_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Ptprc;

Protein name:

Receptor-type tyrosine-protein phosphatase C;

Alternative:

T200;Leukocyte common antigen(L-CA);

CD:

CD45;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with SKAP1. Interacts with DPP4; the interaction is enhanced in a interleukin-12-dependent manner in activated lymphocytes. Binds GANAB and PRKCSH.

Function:

Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN.

Subcellular Location:

Membrane Single-pass type I membrane protein Membrane raft Colocalized with DPP4 in membrane rafts.

Protein Attributes:

Sequence length:

1273

Sequence:

50:

100:

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200:

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1050:

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1150:

1200:

1250:

1273:

ASGSEEPEHS | ANGPMSPALT | PSS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P04157

Pfam:

PF12567

UniGene:

Rn.90166

Pfam:

PF00041

KEGG:

rno:24699

String:

P04157

Uniprot:

P04157

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ELISA Kit for Rat Receptor-type tyrosine-protein phosphatase C

Cat.:

E1030h

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96T

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ELISA Kit for Rat Receptor-type tyrosine-protein phosphatase C

Cat.:

E1030m

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96T

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ELISA Kit for Rat Receptor-type tyrosine-protein phosphatase C

Cat.:

E1030r

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96T

CLIA Kit for Rat Receptor-type tyrosine-protein phosphatase C

Cat.:

U1030m

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Packing:

96T

CLIA Kit for Rat Receptor-type tyrosine-protein phosphatase C

Cat.:

U1030h

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat Receptor-type tyrosine-protein phosphatase C

Cat.:

U1030r

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96T

Polyclonal Antibody for Rat Receptor-type tyrosine-protein phosphatase C

Cat.:

P1030Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Receptor-type tyrosine-protein phosphatase C

Cat.:

P1030Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Receptor-type tyrosine-protein phosphatase C

Cat.:

P1030Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Rat Receptor-type tyrosine-protein phosphatase C

Protein for Rat Receptor-type tyrosine-protein phosphatase C

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Amgen rat EST program."
Amgen EST program
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-147 (ISOFORM 4)
2.

"Lymphocyte specific heterogeneity in the rat leucocyte common antigen (T200) is due to differences in polypeptide sequences near the NH2-terminus."
Barclay A.N. , Jackson D.I. , Willis A.C. , Williams A.F.
EMBO J.6:1259-1264(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 19-218 (ISOFORMS 1; 2; 3 AND 4)
3.

Barclay A.N. , Jackson D.I. , Willis A.C. , Williams A.F.
Submitted (1987-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 19-1273 (ISOFORMS 1; 3; 4 AND 5)
4.

"Evidence from cDNA clones that the rat leukocyte-common antigen (T200) spans the lipid bilayer and contains a cytoplasmic domain of 80,000 Mr."
Thomas M.L. , Barclay A.N. , Gagnon J. , Williams A.F.
Cell41:83-93(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 208-1255 (ISOFORM 1)

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