Gene name:
S1pr5 (Edg8;Nrg1) ;
Protein name:
Sphingosine 1-phosphate receptor 5 (S1P receptor 5;S1P5) ;
Alternative:
Nerve growth factor-regulated G-protein-coupled receptor 1 (NRG-1) ;Endothelial differentiation G-protein-coupled receptor 8 ;Sphingosine 1-phosphate receptor Edg-8 (S1P receptor Edg-8) ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/O)alpha and G(12) subclass of heteromeric G-proteins. Displays antiproliferative effects in transfected CHO-K1 and HEK293 cells.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Protein Attributes:
50:
MESGLLRPAP | VSEVIVLHYN | YTGKLRGARY | QPGAGLRADA | AVCLAVCAFI |
100:
VLENLAVLLV | LGRHPRFHAP | MFLLLGSLTL | SDLLAGAAYA | TNILLSGPLT |
150:
LRLSPALWFA | REGGVFVALA | ASVLSLLAIA | LERHLTMARR | GPAPAASRAR |
200:
TLAMAVAAWG | LSLLLGLLPA | LGWNCLGRLE | ACSTVLPLYA | KAYVLFCVLA |
250:
FLGILAAICA | LYARIYCQVR | ANARRLRAGP | GSRRATSSSR | SRHTPRSLAL |
300:
LRTLSVVLLA | FVACWGPLFL | LLLLDVACPA | RACPVLLQAD | PFLGLAMANS |
350:
LLNPIIYTFT | NRDLRHALLR | LLCCGRGPCN | QDSSNSLQRS | PSAVGPSGGG |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
Pig
ELISA Kit for Rat S1P receptor 5
ELISA Kit for Rat S1P receptor 5
ELISA Kit for Rat S1P receptor 5
ELISA Kit for Rat S1P receptor 5
CLIA Kit for Rat S1P receptor 5
CLIA Kit for Rat S1P receptor 5
CLIA Kit for Rat S1P receptor 5
CLIA Kit for Rat S1P receptor 5
Polyclonal Antibody for Rat S1P receptor 5
Polyclonal Antibody for Rat S1P receptor 5
Polyclonal Antibody for Rat S1P receptor 5
Polyclonal Antibody for Rat S1P receptor 5
Monoclonal Antibody for Rat S1P receptor 5
Monoclonal Antibody for Rat S1P receptor 5
Monoclonal Antibody for Rat S1P receptor 5
Monoclonal Antibody for Rat S1P receptor 5
Protein for Rat S1P receptor 5
Protein for Rat S1P receptor 5
Protein for Rat S1P receptor 5
Protein for Rat S1P receptor 5
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;INDUCTION
tissue :
Adrenal gland .
2.
"Characterization of a novel sphingosine 1-phosphate receptor, Edg-8."
Im D.-S.
,
Heise C.E.
,
Ancellin N.
,
O'Dowd B.F.
,
Shei G.-J.
,
Heavens R.P.
,
Rigby M.R.
,
Hla T.
,
Mandala S.
,
McAllister G.
,
George S.R.
,
Lynch K.R.
J. Biol. Chem.275:14281-14286(2000)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;POSSIBLE FUNCTION
tissue :
Brain .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SIGNAL TRANSDUCTION PATHWAY EXAMINATION
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY