Protein name:
Sodium channel protein type 8 subunit alpha ;
Alternative:
Sodium channel 6 (NaCh6) ;Peripheral nerve protein type 4 (PN4) ;Voltage-gated sodium channel subunit alpha Nav1.6 ;Sodium channel protein type VIII subunit alpha ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Interacts with NEDD4 and NEDD4L.
Function:
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
Subcellular Location:
Membrane
Multi-pass membrane protein
Protein Attributes:
50:
MAARLLAPPG | PDSFKPFTPE | SLANIERRIA | ESKLKKPPKA | DGSHREDDED |
100:
SKPKPNSDLE | AGKSLPFIYG | DIPQGLVAVP | LEDFDPYYLT | QKTFVVLNRG |
150:
KTLFRFSATP | ALYILSPFNL | IRRIAIKILI | HSVFSMIIMC | TILTNCVFMT |
200:
FSNPPEWSKN | VEYTFTGIYT | FESLVKIIAR | GFCIDGFTFL | RDPWNWLDFS |
250:
VIMMAYVTEF | VDLGNVSALR | TFRVLRALKT | ISVIPGLKTI | VGALIQSVKK |
300:
LSDVMILTVF | CLSVFALIGL | QLFMGNLRNK | CVVWPINFNE | SYLENGTRGF |
350:
DWEEYINNKT | NFYMVPGMLE | PLLCGNSSDA | GQCPEGFQCM | KAGRNPNYGY |
400:
TSFDTFSWAF | LALFRLMTQD | YWENLYQLTL | RAAGKTYMIF | FVLVIFVGSF |
450:
YLVNLILAVV | AMAYEEQNQA | TLEEAEQKEA | EFKAMLEQLK | KQQEEAQAAA |
500:
MATSAGTVSE | DAIEEEGEDG | VGSPRSSSEL | SKLSSKSAKE | RRNRRKKRKQ |
550:
KELSEGEEKG | DPEKVFKSES | EDGMRRKAFR | LPDNRIGRKF | SIMNQSLLSI |
600:
PGSPFLSRHN | SKSSIFSFRG | PGRFRDPGSE | NEFADDEHST | VEESEGRRDS |
650:
LFIPIRARER | RSSYSGYSGY | SQCSRSSRIF | PSLRRSVKRN | STVDCNGVVS |
700:
LIGPGSHIGR | LLPEATTEVE | IKKKGPGSLL | VSMDQLASYG | RKDRINSIMS |
750:
VVTNTLVEEL | EESQRKCPPC | WYKFANTFLI | WECHPYWIKL | KEIVNLIVMD |
800:
PFVDLAITIC | IVLNTLFMAM | EHHPMTPQFE | HVLAVGNLVF | TGIFTAEMFL |
850:
KLIAMDPYYY | FQEGWNIFDG | FIVSLSLMEL | SLADVEGLSV | LRSFRLLRVF |
900:
KLAKSWPTLN | MLIKIIGNSV | GALGNLTLVL | AIIVFIFAVV | GMQLFGKSYK |
950:
ECVCKINQEC | KLPRWHMNDF | FHSFLIVFRV | LCGEWIETMW | DCMEVAGQAM |
1000:
CLIVFMMVMV | IGNLVVLNLF | LALLLSSFSA | DNLAATDDDG | EMNNLQISVI |
1050:
RIKKGVAWTK | VKVHAFMQAH | FKQREADEVK | PLDELYEKKA | NCIANHTGVD |
1100:
IHRNGDFQKN | GNGTTSGIGS | SVEKYIIDED | HMSFINNPNL | TVRVPIAVGE |
1150:
SDFENLNTED | VSSESDPEGS | KDKLDDTSSS | EGSTIDIKPE | VEEVPVEQPE |
1200:
EYLDPDACFT | EGCVQRFKCC | QVNIEEGLGK | SWWILRKTCF | LIVEHNWFET |
1250:
FIIFMILLSS | GALAFEDIYI | EQRKTIRTIL | EYADKVFTYI | FILEMLLKWT |
1300:
AYGFVKFFTN | AWCWLDFLIV | AVSLVSLIAN | ALGYSELGAI | KSLRTLRALR |
1350:
PLRALSRFEG | MRVVVNALVG | AIPSIMNVLL | VCLIFWLIFS | IMGVNLFAGK |
1400:
YHYCFNETSE | IRFEIDIVNN | KTDCEKLMEG | NSTEIRWKNV | KINFDNVGAG |
1450:
YLALLQVATF | KGWMDIMYAA | VDSRKPDEQP | DYEGNIYMYI | YFVIFIIFGS |
1500:
FFTLNLFIGV | IIDNFNQQKK | KFGGQDIFMT | EEQKKYYNAM | KKLGSKKPQK |
1550:
PIPRPLNKIQ | GIVFDFVTQQ | AFDIVIMMLI | CLNMVTMMVE | TDTQSKQMEN |
1600:
ILYWINLVFV | IFFTCECVLK | MFALRHYYFT | IGWNIFDFVV | VILSIVGMFL |
1650:
ADIIEKYFVS | PTLFRVIRLA | RIGRILRLIK | GAKGIRTLLF | ALMMSLPALF |
1700:
NIGLLLFLVM | FIFSIFGMSN | FAYVKHEAGI | DDMFNFETFG | NSMICLFQIT |
1750:
TSAGWDGLLL | PILNRPPDCS | LDKEHPGSGF | KGDCGNPSVG | IFFFVSYIII |
1800:
SFLIVVNMYI | AIILENFSVA | TEESADPLSE | DDFETFYEIW | EKFDPDATQF |
1850:
IEYCKLADFA | DALEHPLRVP | KPNTIELIAM | DLPMVSGDRI | HCLDILFAFT |
1900:
KRVLGDSGEL | DILRQQMEER | FVASNPSKVS | YEPITTTLRR | KQEEVSAVVL |
1950:
QRAYRGHLAR | RGFICRKMAS | NKLENGGTHR | DKKESTPSTA | SLPSYDSVTK |
1978:
PDKEKQQRAE | EGRRERAKRQ | KEVRESKC
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Mouse
Human
ELISA Kit for Rat Sodium channel protein type 8 subunit alpha
ELISA Kit for Rat Sodium channel protein type 8 subunit alpha
ELISA Kit for Rat Sodium channel protein type 8 subunit alpha
CLIA Kit for Rat Sodium channel protein type 8 subunit alpha
CLIA Kit for Rat Sodium channel protein type 8 subunit alpha
CLIA Kit for Rat Sodium channel protein type 8 subunit alpha
Polyclonal Antibody for Rat Sodium channel protein type 8 subunit alpha
Polyclonal Antibody for Rat Sodium channel protein type 8 subunit alpha
Polyclonal Antibody for Rat Sodium channel protein type 8 subunit alpha
Monoclonal Antibody for Rat Sodium channel protein type 8 subunit alpha
Monoclonal Antibody for Rat Sodium channel protein type 8 subunit alpha
Monoclonal Antibody for Rat Sodium channel protein type 8 subunit alpha
Protein for Rat Sodium channel protein type 8 subunit alpha
Protein for Rat Sodium channel protein type 8 subunit alpha
Protein for Rat Sodium channel protein type 8 subunit alpha
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);TISSUE SPECIFICITY
tissue :
Spinal ganglion .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH FGF13