SHANK1 Polyclonal Antibody for Human(Homo sapiens) | EIAab.comSHANK1 Polyclonal Antibody for Human(Homo sapiens)

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Index > Protein center > SHANK1(Gene name) > Human

SHANK1 (Gene name),

SH3 and multiple ankyrin repeat domains protein 1 (Protein name ), SHAN1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

SHANK1;

Protein name:

SH3 and multiple ankyrin repeat domains protein 1(Shank1);

Alternative:

Somatostatin receptor-interacting protein(SSTR-interacting protein;SSTRIP);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

May homomultimerize via its SAM domain (By similarity). Interacts with the C-terminus of SSTR2 via the PDZ domain. Interacts with IGSF9, SHARPIN, SPTAN1, HOMER1 and DLGAP1/GKAP isoforms 1 and 2 (By similarity). Part of a complex with DLG4/PSD-95 and DLGAP1/GKAP (By similarity). Interacts with BAIAP2.

Function:

Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction.

Subcellular Location:

Cytoplasm Cell junction synapse postsynaptic cell membrane postsynaptic density Cell junction synapse Postsynaptic density of neuronal cells.

Protein Attributes:

Sequence length:

2161

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2161:

IDRALKFFLE | R

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:50944

STRING:

9606.ENSP00000293441

UniGene:

Hs.274255

SMR:

Q9Y566

String:

Q9Y566

MIM:

604999

Pfam:

PF12796

Uniprot:

Q9Y566

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ELISA Kit for Human Shank1

Cat.:

E14502r

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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ELISA Kit for Human Shank1

Cat.:

E14502m

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Human Shank1

Cat.:

E14502h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Shank1

Cat.:

U14502m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Shank1

Cat.:

U14502h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Shank1

Cat.:

U14502r

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Shank1

Cat.:

P14502Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Shank1

Cat.:

P14502Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Shank1

Cat.:

P14502Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Human Shank1

Protein for Human Shank1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Somatostatin receptor interacting protein defines a novel family of multidomain proteins present in human and rodent brain."
Zitzer H. , Hoenck H.-H. , Baechner D. , Richter D. , Kreienkamp H.-J.
J. Biol. Chem.274:32997-33001(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2 AND 3);INTERACTION WITH SSTR2
tissue: Fetal brain.
tissue: Hippocampus.
tissue: Thalamus.
2.

"The DNA sequence and biology of human chromosome 19."
Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.

"The Shank family of scaffold proteins."
Sheng M. , Kim E.
J. Cell Sci.113:1851-1856(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
4.

"The insulin receptor substrate IRSp53 links postsynaptic shank1 to the small G-protein cdc42."
Soltau M. , Richter D. , Kreienkamp H.-J.
Mol. Cell. Neurosci.21:575-583(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH BAIAP2
5.

"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T. , Jones S. , Wood L.D. , Parsons D.W. , Lin J. , Barber T.D. , Mandelker D. , Leary R.J. , Ptak J. , Silliman N. , Szabo S. , Buckhaults P. , Farrell C. , Meeh P. , Markowitz S.D. , Willis J. , Dawson D. , Willson J.K.V. , more...
Science314:268-274(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS [LARGE SCALE ANALYSIS] ASP-569 AND ARG-2026

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