Snap25 Polyclonal Antibody for Mouse(Mus musculus) | EIAab.comSnap25 Polyclonal Antibody for Mouse(Mus musculus)

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Snap25 (Gene name),

Synaptosomal-associated protein 25 (Protein name ), SNP25_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Snap25(Snap);

Protein name:

Synaptosomal-associated protein 25(SNAP-25);

Alternative:

Synaptosomal-associated 25 kDa protein;Super protein(SUP);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. This complex binds CPLX1. Interacts with TRIM9, RIMS1, SNAPIN and HGS. Binds STXBP6. Found in a ternary complex with STX1A and VAMP8 (By similarity). Found in a complex containing SYT1, SV2B and syntaxin-1. Interacts with CENPF and OTOF.

Function:

t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF.

Subcellular Location:

Cytoplasm perinuclear region Cell membrane Lipid-anchor Cell junction synapse synaptosome Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region.

Protein Attributes:

Sequence length:

206

Sequence:

50:

100:

150:

200:

206:

KMLGSG

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00835

KEGG:

mmu:20614

UniGene:

Mm.45953

String:

P60879

SMR:

P60879

Uniprot:

P60879

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ELISA Kit for Mouse SNAP-25

Cat.:

E15057h

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Packing:

96T

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ELISA Kit for Mouse SNAP-25

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ELISA Kit for Mouse SNAP-25

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ELISA Kit for Mouse SNAP-25

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ELISA Kit for Mouse SNAP-25

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ELISA Kit for Mouse SNAP-25

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CLIA Kit for Mouse SNAP-25

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CLIA Kit for Mouse SNAP-25

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CLIA Kit for Mouse SNAP-25

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CLIA Kit for Mouse SNAP-25

MSDS:

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CLIA Kit for Mouse SNAP-25

MSDS:

Please sign in first.

CLIA Kit for Mouse SNAP-25

Cat.:

U15057h

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse SNAP-25

Monoclonal Antibody for Mouse SNAP-25

Protein for Mouse SNAP-25

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"The identification of a novel synaptosomal-associated protein, SNAP-25, differentially expressed by neuronal subpopulations."
Oyler G.A. , Higgins G.A. , Hart R.A. , Battenberg E. , Billingsley M. , Bloom F.E. , Wilson M.C.
J. Cell Biol.109:3039-3052(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);SUBCELLULAR LOCATION
strain: BALB/c.
2.

"High-throughput sequence identification of gene coding variants within alcohol-related QTLs."
Ehringer M.A. , Thompson J. , Conroy O. , Xu Y. , Yang F. , Canniff J. , Beeson M. , Gordon L. , Bennett B. , Johnson T.E. , Sikela J.M.
Mamm. Genome12:657-663(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
strain: ILS.
strain: ISS.
3.

"The transcriptional landscape of the mammalian genome."
Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain: C57BL/6J.
tissue: Medulla oblongata.
4.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
5.

Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
strain: C57BL/6.
tissue: Eye.
7.

Lubec G. , Kang S.U.
Submitted (2007-04) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 18-31; 60-72; 125-135 AND 143-176;IDENTIFICATION BY MASS SPECTROMETRY
strain: C57BL/6.
tissue: Brain.
8.

"Characterization of the palmitoylation domain of SNAP-25."
Lane S.R. , Liu Y.
J. Neurochem.69:1864-1869(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PALMITOYLATION AT CYS-85; CYS-88; CYS-90 AND CYS-92;MUTAGENESIS OF CYS-85; CYS-88; CYS-90 AND CYS-92
9.

"Snapin: a SNARE-associated protein implicated in synaptic transmission."
Ilardi J.M. , Mochida S. , Sheng Z.-H.
Nat. Neurosci.2:119-124(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SNAPIN
10.

"Differential phosphorylation of SNAP-25 in vivo by protein kinase C and protein kinase A."
Hepp R. , Cabaniols J.-P. , Roche P.A.
FEBS Lett.532:52-56(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT THR-138 AND SER-187
11.

"SV2B regulates synaptotagmin 1 by direct interaction."
Lazzell D.R. , Belizaire R. , Thakur P. , Sherry D.M. , Janz R.
J. Biol. Chem.279:52124-52131(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SYT1; SV2B AND SYNTAXIN-1
12.

"Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse."
Roux I. , Safieddine S. , Nouvian R. , Grati M. , Simmler M.-C. , Bahloul A. , Perfettini I. , Le Gall M. , Rostaing P. , Hamard G. , Triller A. , Avan P. , Moser T. , Petit C.
Cell127:277-289(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH OTOF
strain: BALB/c.
tissue: Cochlea.
13.

"CytLEK1 is a regulator of plasma membrane recycling through its interaction with SNAP-25."
Pooley R.D. , Reddy S. , Soukoulis V. , Roland J.T. , Goldenring J.R. , Bader D.M.
Mol. Biol. Cell17:3176-3186(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH CENPF
14.

"Acrosome formation-associated factor is involved in fertilization."
Hu X.Q. , Ji S.Y. , Li Y.C. , Fan C.H. , Cai H. , Yang J.L. , Zhang C.P. , Chen M. , Pan Z.F. , Hu Z.Y. , Gao F. , Liu Y.X.
Fertil. Steril.93:1482-1492(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH EQTN
15.

"The dysbindin-containing complex (BLOC-1) in brain: developmental regulation, interaction with SNARE proteins and role in neurite outgrowth."
Ghiani C.A. , Starcevic M. , Rodriguez-Fernandez I.A. , Nazarian R. , Cheli V.T. , Chan L.N. , Malvar J.S. , de Vellis J. , Sabatti C. , Dell'Angelica E.C.
Mol. Psychiatry15:204-215(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ASSOCIATION WITH THE BLOC-1 COMPLEX;SUBCELLULAR LOCATION;INTERACTION WITH BLOC1S6
16.

"The synaptic SNARE complex is a parallel four-stranded helical bundle."
Poirier M.A. , Xiao W. , Macosko J.C. , Chan C. , Shin Y.K. , Bennett M.K.
Nat. Struct. Biol.5:765-769(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: 3D-STRUCTURE MODELING OF 18-206 IN COMPLEX WITH VAMP2 AND STX1A

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