Protein name:
Tumor necrosis factor ligand superfamily member 9 ;
Alternative:
4-1BB ligand (4-1BBL) ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.
Subcellular Location:
Membrane
Single-pass type II membrane protein
Protein Attributes:
50:
MEYASDASLD | PEAPWPPAPR | ARACRVLPWA | LVAGLLLLLL | LAAACAVFLA |
100:
CPWAVSGARA | SPGSAASPRL | REGPELSPDD | PAGLLDLRQG | MFAQLVAQNV |
150:
LLIDGPLSWY | SDPGLAGVSL | TGGLSYKEDT | KELVVAKAGV | YYVFFQLELR |
200:
RVVAGEGSGS | VSLALHLQPL | RSAAGAAALA | LTVDLPPASS | EARNSAFGFQ |
250:
GRLLHLSAGQ | RLGVHLHTEA | RARHAWQLTQ | GATVLGLFRV | TPEIPAGLPS |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human Tumor necrosis factor ligand superfamily member 9
ELISA Kit for Human Tumor necrosis factor ligand superfamily member 9
CLIA Kit for Human Tumor necrosis factor ligand superfamily member 9
CLIA Kit for Human Tumor necrosis factor ligand superfamily member 9
Polyclonal Antibody for Human Tumor necrosis factor ligand superfamily member 9
Polyclonal Antibody for Human Tumor necrosis factor ligand superfamily member 9
Monoclonal Antibody for Human Tumor necrosis factor ligand superfamily member 9
Monoclonal Antibody for Human Tumor necrosis factor ligand superfamily member 9
Protein for Human Tumor necrosis factor ligand superfamily member 9
Protein for Human Tumor necrosis factor ligand superfamily member 9
R&D Technical Data
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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References
1.
"Molecular and biological characterization of human 4-1BB and its ligand."
Alderson M.R.
,
Smith C.A.
,
Tough T.W.
,
Davis-Smith T.
,
Armitage R.J.
,
Falk B.
,
Roux E.
,
Baker E.
,
Sutherland G.R.
,
Din W.S.
,
Goodwin R.G.
Eur. J. Immunol.24:2219-2227(1994)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Lung .
3.
"The structure of the trimer of human 4-1BB ligand is unique among members of the tumor necrosis factor superfamily."
Won E.Y.
,
Cha K.
,
Byun J.S.
,
Kim D.U.
,
Shin S.
,
Ahn B.
,
Kim Y.H.
,
Rice A.J.
,
Walz T.
,
Kwon B.S.
,
Cho H.S.
J. Biol. Chem.285:9202-9210(2010)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 80-246;FUNCTION;SUBUNIT