Gene name:
BMPR1A (ACVRLK3;ALK3) ;
Protein name:
Bone morphogenetic protein receptor type-1A (BMP type-1A receptor;BMPR-1A) ;
Alternative:
Serine/threonine-protein kinase receptor R5 (SKR5) ;Activin receptor-like kinase 3 (ALK-3) ;
CD:
CD292 ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MPQLYIYIRL | LGAYLFIISR | VQGQNLDSML | HGTGMKSDSD | QKKSENGVTL |
100:
APEDTLPFLK | CYCSGHCPDD | AINNTCITNG | HCFAIIEEDD | QGETTLASGC |
150:
MKYEGSDFQC | KDSPKAQLRR | TIECCRTNLC | NQYLQPTLPP | VVIGPFFDGS |
200:
IRWLVLLISM | AVCIIAMIIF | SSCFCYKHYC | KSISSRRRYN | RDLEQDEAFI |
250:
PVGESLKDLI | DQSQSSGSGS | GLPLLVQRTI | AKQIQMVRQV | GKGRYGEVWM |
300:
GKWRGEKVAV | KVFFTTEEAS | WFRETEIYQT | VLMRHENILG | FIAADIKGTG |
350:
SWTQLYLITD | YHENGSLYDF | LKCATLDTRA | LLKLAYSAAC | GLCHLHTEIY |
400:
GTQGKPAIAH | RDLKSKNILI | KKNGSCCIAD | LGLAVKFNSD | TNEVDVPLNT |
450:
RVGTKRYMAP | EVLDESLNKN | HFQPYIMADI | YSFGLIIWEM | ARRCITGGIV |
500:
EEYQLPYYNM | VPSDPSYEDM | REVVCVKRLR | PIVSNRWNSD | ECLRAVLKLM |
532:
SECWAHNPAS | RLTALRIKKT | LAKMVESQDV | KI
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
ELISA Kit for Human BMP type-1A receptor
ELISA Kit for Human BMP type-1A receptor
ELISA Kit for Human BMP type-1A receptor
CLIA Kit for Human BMP type-1A receptor
CLIA Kit for Human BMP type-1A receptor
CLIA Kit for Human BMP type-1A receptor
Polyclonal Antibody for Human BMP type-1A receptor
Polyclonal Antibody for Human BMP type-1A receptor
Polyclonal Antibody for Human BMP type-1A receptor
Monoclonal Antibody for Human BMP type-1A receptor
Monoclonal Antibody for Human BMP type-1A receptor
Monoclonal Antibody for Human BMP type-1A receptor
Protein for Human BMP type-1A receptor
Protein for Human BMP type-1A receptor
Protein for Human BMP type-1A receptor
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Cited for : VARIANTS [LARGE SCALE ANALYSIS] THR-2; TYR-58; CYS-443; MET-450 AND GLN-486