Gene name:
Hmgb1 (Hmg-1;Hmg1) ;
Protein name:
High mobility group protein B1 ;
Alternative:
High mobility group protein 1 (HMG-1) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Component of the RAG complex composed of core components RAG1 and RAG2, and associated component HMGB1 or HMGB2.
Function:
DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells.
Subcellular Location:
Nucleus
Cytoplasm
Chromosome
Associated with the plasma membrane of filipodia in process-growing cells, and also deposited into the substrate-attached material.
Protein Attributes:
50:
MGKGDPKKPR | GKMSSYAFFV | QTCREEHKKK | HPDASVNFSE | FSKKCSERWK |
100:
TMSAKEKGKF | EDMAKADKAR | YEREMKTYIP | PKGETKKKFK | DPNAPKRPPS |
150:
AFFLFCSEYR | PKIKGEHPGL | SIGDVAKKLG | EMWNNTAADD | KQPYEKKAAK |
200:
LKEKYEKDIA | AYRAKGKPDA | AKKGVVKAEK | SKKKKEEEDD | EEDEEDEEEE |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Chicken
Pig
Rat
Human
Dog
Bovine
ELISA Kit for Mouse High mobility group protein B1
ELISA Kit for Mouse High mobility group protein B1
ELISA Kit for Mouse High mobility group protein B1
ELISA Kit for Mouse High mobility group protein B1
ELISA Kit for Mouse High mobility group protein B1
ELISA Kit for Mouse High mobility group protein B1
ELISA Kit for Mouse High mobility group protein B1
CLIA Kit for Mouse High mobility group protein B1
CLIA Kit for Mouse High mobility group protein B1
CLIA Kit for Mouse High mobility group protein B1
CLIA Kit for Mouse High mobility group protein B1
CLIA Kit for Mouse High mobility group protein B1
CLIA Kit for Mouse High mobility group protein B1
CLIA Kit for Mouse High mobility group protein B1
Polyclonal Antibody for Mouse High mobility group protein B1
Polyclonal Antibody for Mouse High mobility group protein B1
Polyclonal Antibody for Mouse High mobility group protein B1
Polyclonal Antibody for Mouse High mobility group protein B1
Polyclonal Antibody for Mouse High mobility group protein B1
Polyclonal Antibody for Mouse High mobility group protein B1
Polyclonal Antibody for Mouse High mobility group protein B1
Monoclonal Antibody for Mouse High mobility group protein B1
Monoclonal Antibody for Mouse High mobility group protein B1
Monoclonal Antibody for Mouse High mobility group protein B1
Monoclonal Antibody for Mouse High mobility group protein B1
Monoclonal Antibody for Mouse High mobility group protein B1
Monoclonal Antibody for Mouse High mobility group protein B1
Monoclonal Antibody for Mouse High mobility group protein B1
Protein for Mouse High mobility group protein B1
Protein for Mouse High mobility group protein B1
Protein for Mouse High mobility group protein B1
Protein for Mouse High mobility group protein B1
Protein for Mouse High mobility group protein B1
Protein for Mouse High mobility group protein B1
Protein for Mouse High mobility group protein B1
R&D Technical Data
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12% SDS-PAGE analysis
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Precision
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Recovery
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Linearity
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Citations
[1].
M Liu, Y Yu, H Jiang, et al.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
C3H/He .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
strain :
129/Sv .
tissue :
Liver .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
AKR/J .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 31-43 AND 113-127;IDENTIFICATION BY MASS SPECTROMETRY
strain :
C57BL/6 .
tissue :
Brain .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;IDENTIFICATION IN THE RAG COMPLEX
8.
"SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
Park J.
,
Chen Y.
,
Tishkoff D.X.
,
Peng C.
,
Tan M.
,
Dai L.
,
Xie Z.
,
Zhang Y.
,
Zwaans B.M.
,
Skinner M.E.
,
Lombard D.B.
,
Zhao Y.
Mol. Cell50:919-930(2013)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-30; LYS-43; LYS-90 AND LYS-141;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Embryonic fibroblast .