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Index > Protein center > Hmgb1(Gene name) > Mouse
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  • Hmgb1 (Gene name),
  • High mobility group protein B1 (Protein name ),  HMGB1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Hmgb1(Hmg-1;Hmg1);
    Protein name:
    High mobility group protein B1;
    Alternative:
    High mobility group protein 1(HMG-1);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Component of the RAG complex composed of core components RAG1 and RAG2, and associated component HMGB1 or HMGB2.
    Function:
    DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells.
    Subcellular Location:
    Nucleus Cytoplasm Chromosome Associated with the plasma membrane of filipodia in process-growing cells, and also deposited into the substrate-attached material.
    Protein Attributes:
    Sequence length:
    215
    Sequence:
    50:
    MGKGDPKKPR | GKMSSYAFFV | QTCREEHKKK | HPDASVNFSE | FSKKCSERWK | 
    100:
    TMSAKEKGKF | EDMAKADKAR | YEREMKTYIP | PKGETKKKFK | DPNAPKRPPS | 
    150:
    AFFLFCSEYR | PKIKGEHPGL | SIGDVAKKLG | EMWNNTAADD | KQPYEKKAAK | 
    200:
    LKEKYEKDIA | AYRAKGKPDA | AKKGVVKAEK | SKKKKEEEDD | EEDEEDEEEE | 
    215:
    EEEEDEDEEE | DDDDE
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    String:
    SMR:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse High mobility group protein B1
    Cat.:
    E0399m
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    MSDS:
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    96T
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    ELISA Kit for Mouse High mobility group protein B1
    MSDS:
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    ELISA Kit for Mouse High mobility group protein B1
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    E0399p
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    96T
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    ELISA Kit for Mouse High mobility group protein B1
    Cat.:
    E0399r
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    MSDS:
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    96T
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    ELISA Kit for Mouse High mobility group protein B1
    Cat.:
    E0399h
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    96T
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    ELISA Kit for Mouse High mobility group protein B1
    Cat.:
    E0399d
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse High mobility group protein B1
    Cat.:
    E0399b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse High mobility group protein B1
    Cat.:
    U0399c
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    Packing:
    96T
    CLIA Kit for Mouse High mobility group protein B1
    Cat.:
    U0399b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse High mobility group protein B1
    Cat.:
    U0399d
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse High mobility group protein B1
    Cat.:
    U0399p
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse High mobility group protein B1
    Cat.:
    U0399r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse High mobility group protein B1
    Cat.:
    U0399h
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse High mobility group protein B1
    Cat.:
    U0399m
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    MSDS:
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    Packing:
    96T
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    Polyclonal Antibody for Mouse High mobility group protein B1
    Polyclonal Antibody for Mouse High mobility group protein B1
    Polyclonal Antibody for Mouse High mobility group protein B1
    Polyclonal Antibody for Mouse High mobility group protein B1
    Cat.:
    P0399Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse High mobility group protein B1
    Cat.:
    P0399Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse High mobility group protein B1
    Polyclonal Antibody for Mouse High mobility group protein B1
    Cat.:
    P0399Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse High mobility group protein B1
    Monoclonal Antibody for Mouse High mobility group protein B1
    Monoclonal Antibody for Mouse High mobility group protein B1
    Monoclonal Antibody for Mouse High mobility group protein B1
    Monoclonal Antibody for Mouse High mobility group protein B1
    Monoclonal Antibody for Mouse High mobility group protein B1
    Monoclonal Antibody for Mouse High mobility group protein B1
    Protein for Mouse High mobility group protein B1
    Cat.:
    R0399b
    Price:
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    Packing:
    1mg
    Purity:
    >90%
    Protein for Mouse High mobility group protein B1
    Cat.:
    R0399d
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    Packing:
    1mg
    Purity:
    >90%
    Protein for Mouse High mobility group protein B1
    Cat.:
    R0399m
    Price:
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    Packing:
    1mg
    Purity:
    >90%
    Protein for Mouse High mobility group protein B1
    Cat.:
    R0399p
    Price:
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    Packing:
    1mg
    Purity:
    >90%
    Protein for Mouse High mobility group protein B1
    Cat.:
    R0399r
    Price:
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    Packing:
    1mg
    Purity:
    >90%
    Protein for Mouse High mobility group protein B1
    Cat.:
    R0399h
    Price:
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    Packing:
    1mg
    Purity:
    >90%
    Protein for Mouse High mobility group protein B1

    R&D Technical Data
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    12% SDS-PAGE analysis

              12% SDS-PAGE analysis

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Nucleotide sequence of a mouse cDNA encoding the nonhistone chromosomal high mobility group protein-1 (HMG1)."
      Yotov W.V. , St Arnaud R.
      Nucleic Acids Res.20:3516-3516(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: C3H/He.
    2. 2.
      "The mouse gene coding for high mobility group 1 protein (HMG1)."
      Ferrari S. , Ronfani L. , Calogero S. , Bianchi M.
      J. Biol. Chem.269:28803-28808(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: 129/Sv.
      tissue: Liver.
    3. 3.
      "Molecular cloning, expression analysis, and chromosomal localization of mouse Hmg1-containing sequences."
      Pauken C.M. , Nagle D.L. , Bucan M. , Lo C.W.
      Mamm. Genome5:91-99(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    4. 4.
      "The conserved lymphokine element-0 in the IL5 promoter binds to a high mobility group-1 protein."
      Marrugo J. , Marsh D.G. , Ghosh B.
      Mol. Immunol.33:1119-1125(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: AKR/J.
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    6. 6.
      Lubec G. , Kang S.U.
      Submitted (2007-04) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 31-43 AND 113-127;IDENTIFICATION BY MASS SPECTROMETRY
      strain: C57BL/6.
      tissue: Brain.
    7. 7.
      "Stimulation of V(D)J cleavage by high mobility group proteins."
      van Gent D.C. , Hiom K. , Paull T.T. , Gellert M.
      EMBO J.16:2665-2670(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;IDENTIFICATION IN THE RAG COMPLEX
    8. 8.
      "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
      Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-30; LYS-43; LYS-90 AND LYS-141;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic fibroblast.
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