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Index > Protein center > QKI(Gene name) > Dog
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  • QKI (Gene name),
  • Protein quaking (Protein name ),  QKI_CANFA from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    QKI;
    Protein name:
    Protein quaking(CqkI);
    Alternative:

    Organism:
    Dog (Canis familiarisCanis lupus familiaris). 
    General Annotation
    Sub Unit:
    Homodimer. Does not require RNA to homodimerize. Able to heterodimerize with BICC1.
    Function:
    RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor.
    Subcellular Location:
    Nucleus Cytoplasm
    Protein Attributes:
    Sequence length:
    341
    Sequence:
    50:
    MVGEMETKEK | PKPTPDYLMQ | LMNDKKLMSS | LPNFCGIFNH | LERLLDEEIS | 
    100:
    RVRKDMYNDT | LNGSTEKRSA | ELPDAVGPIV | QLQEKLYVPV | KEYPDFNFVG | 
    150:
    RILGPRGLTA | KQLEAETGCK | IMVRGKGSMR | DKKKEEQNRG | KPNWEHLNED | 
    200:
    LHVLITVEDA | QNRAEIKLKR | AVEEVKKLLV | PAAEGEDSLK | KMQLMELAIL | 
    250:
    NGTYRDANIK | SPALAFSLAA | TAQAAPRIIT | GPAPVLPPAA | LRTPTPAGPT | 
    300:
    IMPLIRQIQT | AVMPNGTPHP | TAAIVPPGPE | AGLIYTPYEY | PYTLAPATSI | 
    341:
    LEYPIEPSGV | LGAVATKVRR | HDMRVHPYQR | IVTADRAATG | N
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Dog CqkI
    ELISA Kit for Dog CqkI
    ELISA Kit for Dog CqkI
    ELISA Kit for Dog CqkI
    ELISA Kit for Dog CqkI
    ELISA Kit for Dog CqkI
    ELISA Kit for Dog CqkI
    CLIA Kit for Dog CqkI
    CLIA Kit for Dog CqkI
    CLIA Kit for Dog CqkI
    CLIA Kit for Dog CqkI
    CLIA Kit for Dog CqkI
    CLIA Kit for Dog CqkI
    CLIA Kit for Dog CqkI
    Polyclonal Antibody for Dog CqkI
    Polyclonal Antibody for Dog CqkI
    Polyclonal Antibody for Dog CqkI
    Polyclonal Antibody for Dog CqkI
    Polyclonal Antibody for Dog CqkI
    Polyclonal Antibody for Dog CqkI
    Polyclonal Antibody for Dog CqkI
    Monoclonal Antibody for Dog CqkI
    Monoclonal Antibody for Dog CqkI
    Monoclonal Antibody for Dog CqkI
    Monoclonal Antibody for Dog CqkI
    Monoclonal Antibody for Dog CqkI
    Monoclonal Antibody for Dog CqkI
    Monoclonal Antibody for Dog CqkI
    Protein for Dog CqkI
    Protein for Dog CqkI
    Protein for Dog CqkI
    Protein for Dog CqkI
    Protein for Dog CqkI
    Protein for Dog CqkI
    Protein for Dog CqkI

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    References
    1. 1.
      "Nucleotide sequence of cDNA encoding for canine and feline quaking protein."
      Murata T. , Yamashiro Y. , Kondo T. , Une S. , Nakaichi M.
      J. Jpn. Vet. Med. Assoc.55:505-508(2002)
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Beagle.
      tissue: Blood.
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