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Index > Protein center > TP53I3(Gene name) > Human
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  • TP53I3 (Gene name),
  • Quinone oxidoreductase PIG3 (Protein name ),  QORX_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    TP53I3(PIG3);
    Protein name:
    Quinone oxidoreductase PIG3;
    Alternative:
    p53-induced gene 3 protein;Tumor protein p53-inducible protein 3;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    May be involved in the generation of reactive oxygen species (ROS). Has low NADPH-dependent naphtoquinone reductase activity, with a preference for 1,2-naphtoquinone over 1,4-naphtoquinone. Has low NADPH-dependent diamine reductase activity (in vitro).
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    332
    Sequence:
    50:
    MLAVHFDKPG | GPENLYVKEV | AKPSPGEGEV | LLKVAASALN | RADLMQRQGQ | 
    100:
    YDPPPGASNI | LGLEASGHVA | ELGPGCQGHW | KIGDTAMALL | PGGGQAQYVT | 
    150:
    VPEGLLMPIP | EGLTLTQAAA | IPEAWLTAFQ | LLHLVGNVQA | GDYVLIHAGL | 
    200:
    SGVGTAAIQL | TRMAGAIPLV | TAGSQKKLQM | AEKLGAAAGF | NYKKEDFSEA | 
    250:
    TLKFTKGAGV | NLILDCIGGS | YWEKNVNCLA | LDGRWVLYGL | MGGGDINGPL | 
    300:
    FSKLLFKRGS | LITSLLRSRD | NKYKQMLVNA | FTEQILPHFS | TEGPQRLLPV | 
    332:
    LDRIYPVTEI | QEAHKYMEAN | KNIGKIVLEL | PQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    MIM:
    SMR:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Quinone oxidoreductase PIG3
    Cat.:
    E3462h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Quinone oxidoreductase PIG3
    Cat.:
    U3462h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Quinone oxidoreductase PIG3
    Cat.:
    P3462Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Quinone oxidoreductase PIG3
    Protein for Human Quinone oxidoreductase PIG3

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    Recovery
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    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1);INDUCTION BY TP53
      tissue: Colon cancer.
    2. 2.
      "UV-dependent alternative splicing uncouples p53 activity and PIG3 gene function through rapid proteolytic degradation."
      Nicholls C.D. , Shields M.A. , Lee P.W.K. , Robbins S.M. , Beattie T.L.
      J. Biol. Chem.279:24171-24178(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      tissue: Mammary tumor.
    3. 3.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    4. 4.
      Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S.
      Submitted (2005-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Gastric mucosa.
    5. 5.
      NIEHS SNPs program
      Submitted (2005-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    6. 6.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Muscle.
    9. 9.
      Bienvenut W.V. , Vousden K.H. , Lukashchuk N.
      Submitted (2008-03) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-33; 163-176; 184-203; 259-267; 297-303 AND 326-332;ACETYLATION AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Lung carcinoma.
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    11. 11.
      "Three-dimensional structure and enzymatic function of proapoptotic human p53-inducible quinone oxidoreductase PIG3."
      Porte S. , Valencia E. , Yakovtseva E.A. , Borras E. , Shafqat N. , Debreczeny J.E. , Pike A.C.W. , Oppermann U. , Farres J. , Fita I. , Pares X.
      J. Biol. Chem.284:17194-17205(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) IN COMPLEX WITH NADP;FUNCTION;SUBUNIT;CATALYTIC ACTIVITY;BIOPHYSICOCHEMICAL PROPERTIES;MUTAGENESIS OF TYR-51 AND SER-151
    12. 12.
      "Somatic sequence alterations in twenty-one genes selected by expression profile analysis of breast carcinomas."
      Chanock S.J. , Burdett L. , Yeager M. , Llaca V. , Langeroed A. , Presswalla S. , Kaaresen R. , Strausberg R.L. , Gerhard D.S. , Kristensen V. , Perou C.M. , Boerresen-Dale A.-L.
      Breast Cancer Res.9:R5-R5(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT LYS-180
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