Rarb ELISA Kit for Mouse(Mus musculus) | EIAab.comRarb ELISA Kit for Mouse(Mus musculus) | EIAab.com

Language:

[Sign in] [Register]

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Rarb(Gene name) > Mouse

Add your favorite

Rarb (Gene name),

Retinoic acid receptor beta (Protein name ), RARB_MOUSE from NCBI database.

top

Come back to page head.

|

General Annotation

|

Antigen Annotation

|

3D

|

Predicted Eptitope

|

Vaild Sequence

|

Related Databases

|

Feedback

Gene name:

Rarb(Nr1b2);

Protein name:

Retinoic acid receptor beta(RAR-beta);

Alternative:

Nuclear receptor subfamily 1 group B member 2;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homodimer (By similarity). Heterodimer; with a RXR molecule. Binds DNA preferentially as a RAR/RXR heterodimer. Interacts weakly with NCOR2.

Function:

Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors (By similarity). In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

482

Sequence:

50:

MSTSSHACPV | PAVRGHMTHY | PAAPYPLLFP | PVIRGLSLPP | LHGLHGHPPP |

100:

SGCSTPSPAS | VGQACQRTTG | GSQFAASTKW | TPSLNAAIET | QSTSSEELVP |

150:

SPPSPLPPPR | VYKPCFVCQD | KSSGYHYGVS | ACEGCKGFFR | RSIQKNMIYT |

200:

CHRDKNCVIN | KVTRNRCQYC | RLQKCFEVGM | SKESVRNDRN | KKKKEPSKQE |

250:

CTESYEMTAE | LDDLTEKIRK | AHQETFPSLC | QLGKYTTNSS | ADHRVRLDLG |

300:

LWDKFSELAT | KCIIKIVEFA | KRLPGFTGLT | IADQITLLKA | ACLDILILRI |

350:

CTRYTPEQDT | MTFSDGLTLN | RTQMHNAGFG | PLTDLVFTFA | NQLLPLEMDD |

400:

TETGLLSAIC | LICGDRQDLE | EPTKVDKLQE | PLLEALKIYI | RKRRPSKPHM |

450:

FPKILMKITD | LRSISAKGAE | RVITLKMEIP | GSMPPLIQEM | LENSEGHEPL |

482:

TPSSSGNIAE | HSPSVSPSSV | ENSGVSQSPL | LQ

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

SMR:

Pfam:

String:

KEGG:

UniGene:

Uniprot:

FOR

ELISA Kit for Mouse RAR-beta

Cat.:

E10642m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Mouse RAR-beta

Cat.:

E10642h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Mouse RAR-beta

MSDS:

Please sign in first.

CLIA Kit for Mouse RAR-beta

MSDS:

Please sign in first.

CLIA Kit for Mouse RAR-beta

Cat.:

U10642h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Mouse RAR-beta

Cat.:

U10642m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

Polyclonal Antibody for Mouse RAR-beta

Polyclonal Antibody for Mouse RAR-beta

Polyclonal Antibody for Mouse RAR-beta

Cat.:

P10642Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse RAR-beta

Monoclonal Antibody for Mouse RAR-beta

Monoclonal Antibody for Mouse RAR-beta

Protein for Mouse RAR-beta

Protein for Mouse RAR-beta

Protein for Mouse RAR-beta

R&D Technical Data

s

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

s

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Intra-Assay CV: ≤5.8%

Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

Inter-Assay CV: ≤7.2%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Intra-Assay CV: ≤3.9%

Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

Inter-Assay CV: ≤7.7%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

Recovery was determined by spiking various levels of RARB into serum and plasma .

Sample Type	Average(%)	Recovery Range(%)
Serum	96	92-103
Plasma	98	93-105

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery was determined by spiking various levels of ACE into serum and plasma .

Sample Type	Average(%)	Recovery Range(%)
Serum	99	91-103
Plasma	98	93-106

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

The linearity of the kit was assayed by testing samples spiked with appropriate concentration of RARB and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample	1：2	1:4	1:8	1:16
serum(n=5)	90-102%	92-101%	91-99%	93-100%
EDTA plasma(n=5)	94-103%	91-105%	92-106%	94-102%
heparin plasma(n=5)	93-105%	90-107%	95-101%	91-107%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ACE and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample	1：2	1:4	1:8	1:16
serum(n=5)	92-105%	90-101%	95-105%	92-109%
EDTA plasma(n=5)	89-95%	93105%	89-94%	90-106%
heparin plasma(n=5)	93-104%	94-110%	101-111%	91-110%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Differentially expressed isoforms of the mouse retinoic acid receptor beta generated by usage of two promoters and alternative splicing."
Zelent A. , Mendelsohn C. , Kastner P. , Krust A. , Garnier J.-M. , Ruffenach F. , Leroy P. , Chambon P.
EMBO J.10:71-81(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS BETA-1; BETA-2 AND BETA-3)
strain: C57BL/C.
2.

"Cloning of murine alpha and beta retinoic acid receptors and a novel receptor gamma predominantly expressed in skin."
Zelent A. , Krust A. , Petkovich M. , Kastner P. , Chambon P.
Nature339:714-717(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM BETA-2)
3.

"Cloning of several genes coding for retinoic acid nuclear receptors in the mouse embryonal carcinoma cell line PCC7-MZ1."
Heiermann R. , Rentrop M. , Lang E. , Maelicke A.
J. Recept. Res.13:693-709(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM BETA-2)
4.

"RAR-beta 4, a retinoic acid receptor isoform is generated from RAR-beta 2 by alternative splicing and usage of a CUG initiator codon."
Nagpal S. , Zelent A. , Chambon P.
Proc. Natl. Acad. Sci. U.S.A.89:2718-2722(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM BETA-4)
5.

"Mouse and human retinoic acid receptor beta 2 promoters: sequence comparison and localization of retinoic acid responsiveness."
Shen S. , Kruyt F.A. , den Hertog J. , van der Saag P.T. , Kruijer W.
DNA Seq.2:111-119(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-48 (ISOFORM BETA-2)
6.

"Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse."
Williams J.A. , Kondo N. , Okabe T. , Takeshita N. , Pilchak D.M. , Koyama E. , Ochiai T. , Jensen D. , Chu M.L. , Kane M.A. , Napoli J.L. , Enomoto-Iwamoto M. , Ghyselinck N. , Chambon P. , Pacifici M. , Iwamoto M.
Dev. Biol.328:315-327(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION
7.

"Characterization of the interaction between retinoic acid receptor/retinoid X receptor (RAR/RXR) heterodimers and transcriptional coactivators through structural and fluorescence anisotropy studies."
Pogenberg V. , Guichou J.F. , Vivat-Hannah V. , Kammerer S. , Perez E. , Germain P. , de Lera A.R. , Gronemeyer H. , Royer C.A. , Bourguet W.
J. Biol. Chem.280:1625-1633(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS) OF 180-482 IN COMPLEX WITH RXRA AND MED1

Product Feedback Wall

Hot Genes: Atf2 ASPRO ACE ALCAM C19orf80 Trap1a Gdf5

Top Searches: Ubiquitin-protein ligase metalloproteinase Ubiquitin ELISA Alpha Tumor necrosis Asprosin TRAP1A

Why choose EIAAB: Our products have been quoted by many publications in famous journals such as Cell; Cell Metabolism; Hepatology; Biomaterials.more

Further Information: About us Protein center Bank account Distributors Terms & Conditions Career eiaab.com.cn

Copyright & copy www.eiaab.com2006-2016 All Rights Reserved EIAab Email:eiaab@eiaab.com

鄂ICP备10015095号-1

鄂公网安备 42018502005535号