Hras1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comHras1 ELISA Kit for Rat(Rattus norvegicus)

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Hras1 (Gene name),

GTPase HRas (Protein name ), RASH_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Hras1(Hras);

Protein name:

GTPase HRas;

Alternative:

Transforming protein p21;H-Ras-1;p21ras;c-H-ras;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Forms a signaling complex with RASGRP1 and DGKZ. In its GTP-bound form interacts with PLCE1. Interacts with TBC1D10C. Interacts with RGL3 and RASSF5. Interacts with HSPD1. Interacts with PDE6D. Interacts with IKZF3. Interacts with GNB2L1 (By similarity). Found in a complex with at least BRAF, HRAS1, MAP2K1, MAPK3 and RGS14. Interacts (active GTP-bound form) with RGS14 (via RBD 1 domain).

Function:

Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.

Subcellular Location:

Cell membrane Cell membrane Lipid-anchor Cytoplasmic side Golgi apparatus Golgi apparatus membrane Lipid-anchor Shuttles between the plasma membrane and the Golgi apparatus (By similarity). The active GTP-bound form is localized most strongly to membranes than the inactive GDP-bound form.

Protein Attributes:

Sequence length:

189

Sequence:

50:

100:

150:

189:

GVEDAFYTLV | REIRQHKLRK | LNPPDESGPG | CMSCKCVLS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00071

String:

P20171

UniGene:

Rn.102180

SMR:

P20171

STRING:

10116.ENSRNOP00000022363

KEGG:

rno:293621

Uniprot:

P20171

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ELISA Kit for Rat GTPase HRas

Cat.:

E1294c

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Manual:

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Packing:

96T

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ELISA Kit for Rat GTPase HRas

Cat.:

E1294r

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Packing:

96T

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ELISA Kit for Rat GTPase HRas

Cat.:

E1294m

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Manual:

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Packing:

96T

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CLIA Kit for Rat GTPase HRas

Cat.:

U1294m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat GTPase HRas

Cat.:

U1294r

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat GTPase HRas

Cat.:

U1294c

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat GTPase HRas

Cat.:

P1294Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat GTPase HRas

Cat.:

P1294Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat GTPase HRas

Monoclonal Antibody for Rat GTPase HRas

Protein for Rat GTPase HRas

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Nucleotide sequence of the two rat cellular rasH genes."
Ruta M. , Wolford R. , Dhar R. , Defeo-Jones D. , Ellis R.W. , Scolnick E.M.
Mol. Cell. Biol.6:1706-1710(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
tissue: Thymus.
3.

"Nucleotide sequence and characterization of the 5' flanking region of the rat Ha-ras protooncogene."
Damante G. , Filetti S. , Rapoport B.
Proc. Natl. Acad. Sci. U.S.A.84:774-778(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-37
4.

"Posttranslational modification of the Ha-ras oncogene protein: evidence for a third class of protein carboxyl methyltransferases."
Clarke S. , Vogel J.P. , Deschenes R.J. , Stock J.
Proc. Natl. Acad. Sci. U.S.A.85:4643-4647(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ISOPRENYLATION AT CYS-186;CLEAVAGE;METHYLATION AT CYS-186
5.

"Phospholipase C(epsilon): a novel Ras effector."
Kelley G.G. , Reks S.E. , Ondrako J.M. , Smrcka A.V.
EMBO J.20:743-754(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PLCE1;MUTAGENESIS OF ASN-26; THR-35; GLU-37; ASP-38; TYR-40; GLN-61 AND CYS-186
6.

"Regulator of G-protein signaling 14 (RGS14) is a selective H-Ras effector."
Willard F.S. , Willard M.D. , Kimple A.J. , Soundararajan M. , Oestreich E.A. , Li X. , Sowa N.A. , Kimple R.J. , Doyle D.A. , Der C.J. , Zylka M.J. , Snider W.D. , Siderovski D.P.
PLoS ONE4:E4884-E4884(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A COMPLEX WITH BRAF; MAP2K1; MAPK3 AND RGS14;INTERACTION WITH RGS14
7.

"RGS14 is a multifunctional scaffold that integrates G protein and Ras/Raf MAPkinase signalling pathways."
Shu F.J. , Ramineni S. , Hepler J.R.
Cell. Signal.22:366-376(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RGS14;SUBCELLULAR LOCATION

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