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Index > Protein center > RABGAP1(Gene name) > Human
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  • RABGAP1 (Gene name),
  • Rab GTPase-activating protein 1 (Protein name ),  RBGP1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    RABGAP1(HSPC094);
    Protein name:
    Rab GTPase-activating protein 1;
    Alternative:
    Rab6 GTPase-activating protein GAPCenA;GAP and centrosome-associated protein;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with RAB6A and tubulin gamma.
    Function:
    May act as a GTPase-activating protein of RAB6A. May play a role in microtubule nucleation by centrosome. May participate in a RAB6A-mediated pathway involved in the metaphase-anaphase transition.
    Subcellular Location:
    Cytoplasm cytosol Cytoplasm cytoskeleton centrosome Predominantly cytosolic but also associated with the centrosome.
    Protein Attributes:
    Sequence length:
    1069
    Sequence:
    50:
    MDDKASVGKI | SVSSDSVSTL | NSEDFVLVSR | QGDETPSTNN | GSDDEKTGLK | 
    100:
    IVGNGSEQQL | QKELADVLMD | PPMDDQPGEK | ELVKRSQLDG | EGDGPLSNQL | 
    150:
    SASSTINPVP | LVGLQKPEMS | LPVKPGQGDS | EASSPFTPVA | DEDSVVFSKL | 
    200:
    TYLGCASVNA | PRSEVEALRM | MSILRSQCQI | SLDVTLSVPN | VSEGIVRLLD | 
    250:
    PQTNTEIANY | PIYKILFCVR | GHDGTPESDC | FAFTESHYNA | ELFRIHVFRC | 
    300:
    EIQEAVSRIL | YSFATAFRRS | AKQTPLSATA | APQTPDSDIF | TFSVSLEIKE | 
    350:
    DDGKGYFSAV | PKDKDRQCFK | LRQGIDKKIV | IYVQQTTNKE | LAIERCFGLL | 
    400:
    LSPGKDVRNS | DMHLLDLESM | GKSSDGKSYV | ITGSWNPKSP | HFQVVNEETP | 
    450:
    KDKVLFMTTA | VDLVITEVQE | PVRFLLETKV | RVCSPNERLF | WPFSKRSTTE | 
    500:
    NFFLKLKQIK | QRERKNNTDT | LYEVVCLESE | SERERRKTTA | SPSVRLPQSG | 
    550:
    SQSSVIPSPP | EDDEEEDNDE | PLLSGSGDVS | KECAEKILET | WGELLSKWHL | 
    600:
    NLNVRPKQLS | SLVRNGVPEA | LRGEVWQLLA | GCHNNDHLVE | KYRILITKES | 
    650:
    PQDSAITRDI | NRTFPAHDYF | KDTGGDGQDS | LYKICKAYSV | YDEEIGYCQG | 
    700:
    QSFLAAVLLL | HMPEEQAFSV | LVKIMFDYGL | RELFKQNFED | LHCKFYQLER | 
    750:
    LMQEYIPDLY | NHFLDISLEA | HMYASQWFLT | LFTAKFPLYM | VFHIIDLLLC | 
    800:
    EGISVIFNVA | LGLLKTSKDD | LLLTDFEGAL | KFFRVQLPKR | YRSEENAKKL | 
    850:
    MELACNMKIS | QKKLKKYEKE | YHTMREQQAQ | QEDPIERFER | ENRRLQEANM | 
    900:
    RLEQENDDLA | HELVTSKIAL | RKDLDNAEEK | ADALNKELLM | TKQKLIDAEE | 
    950:
    EKRRLEEESA | QLKEMCRREL | DKAESEIKKN | SSIIGDYKQI | CSQLSERLEK | 
    1000:
    QQTANKVEIE | KIRQKVDDCE | RCREFFNKEG | RVKGISSTKE | VLDEDTDEEK | 
    1050:
    ETLKNQLREM | ELELAQTKLQ | LVEAECKIQD | LEHHLGLALN | EVQAAKKTWF | 
    1069:
    NRTLSSIKTA | TGVQGKETC
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    SMR:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Rab GTPase-activating protein 1
    ELISA Kit for Human Rab GTPase-activating protein 1
    CLIA Kit for Human Rab GTPase-activating protein 1
    CLIA Kit for Human Rab GTPase-activating protein 1
    Polyclonal Antibody for Human Rab GTPase-activating protein 1
    Polyclonal Antibody for Human Rab GTPase-activating protein 1
    Monoclonal Antibody for Human Rab GTPase-activating protein 1
    Monoclonal Antibody for Human Rab GTPase-activating protein 1
    Protein for Human Rab GTPase-activating protein 1
    Protein for Human Rab GTPase-activating protein 1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Characterization of GAPCenA, a GTPase activating protein for Rab6, part of which associates with the centrosome."
      Cuif M.-H. , Possmayer F. , Zander H. , Bordes N. , Jollivet F. , Couedel-Courteille A. , Janoueix-Lerosey I. , Langsley G. , Bornens M. , Goud B.
      EMBO J.18:1772-1782(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;INTERACTION WITH RAB6A AND TUBULIN GAMMA;SUBCELLULAR LOCATION
      tissue: Placenta.
    2. 2.
      "Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity."
      Ishibashi K. , Kanno E. , Itoh T. , Fukuda M.
      Genes Cells14:41-52(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    3. 3.
      "Human partial CDS from CD34+ stem cells."
      Zhang Q.H. , Ye M. , Zhou J. , Shen Y. , Wu X.Y. , Guan Z.Q. , Wang L. , Fan H.Y. , Mao Y.F. , Dai M. , Huang Q.H. , Chen S.J. , Chen Z.
      Submitted (1999-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
      tissue: Umbilical cord blood.
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 4)
      tissue: Mammary gland.
      tissue: Testis.
    5. 5.
      "DNA sequence and analysis of human chromosome 9."
      Humphray S.J. , Oliver K. , Hunt A.R. , Plumb R.W. , Loveland J.E. , Howe K.L. , Andrews T.D. , Searle S. , Hunt S.E. , Scott C.E. , Jones M.C. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Ashwell R.I.S. , Babbage A.K. , Babbage S. , Bagguley C.L. , more...
      Nature429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Placenta.
      tissue: Uterus.
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 824-1069 (ISOFORM 1)
      tissue: Uterus.
    9. 9.
      "A role for the Rab6A' GTPase in the inactivation of the Mad2-spindle checkpoint."
      Miserey-Lenkei S. , Couedel-Courteille A. , Del Nery E. , Bardin S. , Piel M. , Racine V. , Sibarita J.-B. , Perez F. , Bornens M. , Goud B.
      EMBO J.25:278-289(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-996;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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