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Index > Protein center > RBM22(Gene name) > Human
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  • RBM22 (Gene name),
  • Pre-mRNA-splicing factor RBM22 (Protein name ),  RBM22_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Vaild Sequence
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  • Gene name:
    RBM22(199G4;ZC3H16);
    Protein name:
    Pre-mRNA-splicing factor RBM22;
    Alternative:
    Zinc finger CCCH domain-containing protein 16;RNA-binding motif protein 22;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Identified in the spliceosome C complex. Interacts with PDCD6.
    Function:
    Involved in pre-mRNA splicing (Probable). May translocate the cytosolic calcium-binding protein PDCD6 in the nucleus.
    Subcellular Location:
    Nucleus Cytoplasm Mainly located in the nucleus. May be shuttling between the nucleus and the cytosol.
    Protein Attributes:
    Sequence length:
    420
    Sequence:
    50:
    MATSLGSNTY | NRQNWEDADF | PILCQTCLGE | NPYIRMTKEK | YGKECKICAR | 
    100:
    PFTVFRWCPG | VRMRFKKTEV | CQTCSKLKNV | CQTCLLDLEY | GLPIQVRDAG | 
    150:
    LSFKDDMPKS | DVNKEYYTQN | MEREISNSDG | TRPVGMLGKA | TSTSDMLLKL | 
    200:
    ARTTPYYKRN | RPHICSFWVK | GECKRGEECP | YRHEKPTDPD | DPLADQNIKD | 
    250:
    RYYGINDPVA | DKLLKRASTM | PRLDPPEDKT | ITTLYVGGLG | DTITETDLRN | 
    300:
    HFYQFGEIRT | ITVVQRQQCA | FIQFATRQAA | EVAAEKSFNK | LIVNGRRLNV | 
    350:
    KWGRSQAARG | KEKEKDGTTD | SGIKLEPVPG | LPGALPPPPA | AEEEASANYF | 
    400:
    NLPPSGPPAV | VNIALPPPPG | IAPPPPPGFG | PHMFHPMGPP | PPFMRAPGPI | 
    420:
    HYPSQDPQRM | GAHAGKHSSP | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    MIM:
    KEGG:
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Pre-mRNA-splicing factor RBM22
    ELISA Kit for Human Pre-mRNA-splicing factor RBM22
    ELISA Kit for Human Pre-mRNA-splicing factor RBM22
    ELISA Kit for Human Pre-mRNA-splicing factor RBM22
    ELISA Kit for Human Pre-mRNA-splicing factor RBM22
    CLIA Kit for Human Pre-mRNA-splicing factor RBM22
    CLIA Kit for Human Pre-mRNA-splicing factor RBM22
    CLIA Kit for Human Pre-mRNA-splicing factor RBM22
    CLIA Kit for Human Pre-mRNA-splicing factor RBM22
    CLIA Kit for Human Pre-mRNA-splicing factor RBM22
    Polyclonal Antibody for Human Pre-mRNA-splicing factor RBM22
    Polyclonal Antibody for Human Pre-mRNA-splicing factor RBM22
    Polyclonal Antibody for Human Pre-mRNA-splicing factor RBM22
    Polyclonal Antibody for Human Pre-mRNA-splicing factor RBM22
    Polyclonal Antibody for Human Pre-mRNA-splicing factor RBM22
    Monoclonal Antibody for Human Pre-mRNA-splicing factor RBM22
    Monoclonal Antibody for Human Pre-mRNA-splicing factor RBM22
    Monoclonal Antibody for Human Pre-mRNA-splicing factor RBM22
    Monoclonal Antibody for Human Pre-mRNA-splicing factor RBM22
    Monoclonal Antibody for Human Pre-mRNA-splicing factor RBM22
    Protein for Human Pre-mRNA-splicing factor RBM22
    Protein for Human Pre-mRNA-splicing factor RBM22
    Protein for Human Pre-mRNA-splicing factor RBM22
    Protein for Human Pre-mRNA-splicing factor RBM22
    Protein for Human Pre-mRNA-splicing factor RBM22

    R&D Technical Data
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    Precision
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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Uterus.
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Mammary gland.
      tissue: Umbilical cord blood.
    3. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Placenta.
    5. 6.
      "Transcriptional map of the Treacher Collins candidate gene region."
      Loftus S.K. , Dixon J. , Koprivnikar K. , Dixon M.J. , Wasmuth J.J.
      Genome Res.6:26-34(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 126-420
      tissue: Brain.
    6. 7.
      "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis."
      Jurica M.S. , Licklider L.J. , Gygi S.P. , Grigorieff N. , Moore M.J.
      RNA8:426-439(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY;IDENTIFICATION IN THE SPLICEOSOMAL C COMPLEX
    7. 8.
      "Nuclear translocation of the calcium-binding protein ALG-2 induced by the RNA-binding protein RBM22."
      Montaville P. , Dai Y. , Cheung C.Y. , Giller K. , Becker S. , Michalak M. , Webb S.E. , Miller A.L. , Krebs J.
      Biochim. Biophys. Acta1763:1335-1343(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH PDCD6
    8. 9.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
    9. 10.
      "The influence of calcium signaling on the regulation of alternative splicing."
      Krebs J.
      Biochim. Biophys. Acta1793:979-984(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;MUTAGENESIS OF LYS-170 AND LYS-324
    10. 11.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-212;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    11. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    12. 13.
      "Stress induced subcellular distribution of ALG-2, RBM22 and hSlu7."
      Janowicz A. , Michalak M. , Krebs J.
      Biochim. Biophys. Acta1813:1045-1049(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
    13. 14.
      "Cwc2 and its human homologue RBM22 promote an active conformation of the spliceosome catalytic centre."
      Rasche N. , Dybkov O. , Schmitzova J. , Akyildiz B. , Fabrizio P. , Luhrmann R.
      EMBO J.31:1591-1604(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;RNA-BINDING
    14. 15.
      "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
      Bienvenut W.V. , Sumpton D. , Martinez A. , Lilla S. , Espagne C. , Meinnel T. , Giglione C.
      Mol. Cell. Proteomics11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    15. 16.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    16. 17.
      "Solution structure of RNA binding domain in pre-mRNA-splicing factor RBM22."
      RIKEN structural genomics initiative (RSGI)
      Submitted (2007-10) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 227-304
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