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Index > Protein center > Rec8(Gene name) > Rat
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  • Rec8 (Gene name),
  • Meiotic recombination protein REC8 homolog (Protein name ),  REC8_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Rec8(Rec8L1);
    Protein name:
    Meiotic recombination protein REC8 homolog;
    Alternative:
    Cohesin Rec8p;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts (phosphorylated and unphosphorylated form) with SMC3. Interacts with SYCP3. Interacts (phosphorylated and unphosphorylated form) with SMC1B. Does not interact with SMC1A (By similarity). Interacts with RAD51.
    Function:
    Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II.
    Subcellular Location:
    Nucleus Chromosome Chromosome centromere In meiotic chromosomes, localized along axial elements in prophase from the leptotene to diplotene stages. At later prophase stages, diakinesis and metaphase I, localized along interstitial axes of chromosomes including both centromere and arm regions. No longer detected in arm regions in anaphase I but persists on centromere regions until metaphase II.
    Protein Attributes:
    Sequence length:
    593
    Sequence:
    50:
    MFYYPNVLQR | HTGCFATIWL | AATRGSRLVK | REYLKVNVVK | TCEEILNYVL | 
    100:
    VRVQPPMPGL | PRPRFSLYLS | AQLQIGVIRV | YFQQCQYLVE | DIQHILEHLH | 
    150:
    RAQLRIRIDM | EEADLPSLLL | PNCLAMMETL | EDAPEPFFGT | MSVDPTLPSP | 
    200:
    FDIPQIRHLL | EAATPEKIRE | ETLPEATPEP | RKPDRTLAMV | QSPEVITLQE | 
    250:
    AEPIRMLRIE | GEQDLPEISR | GDLDLLIAEE | DDAILLEERQ | RGRLLRQRRA | 
    300:
    SPPLDESKEE | PRALEGDGLV | SSLSPPAPAQ | VEGIREPLPD | QAFPPEVQKM | 
    350:
    PGWEPGVLLT | EVTPPQELRL | PAPPSIEKRP | PSPQRPPRRR | RRGRQLLFWD | 
    400:
    KETQISREKF | EEQLQTGAHC | CEYPVVQPPK | RKLMSPAELF | RTPTLSGWLS | 
    450:
    PELLALWTHC | AQVPPRMLRQ | RPQLETEETV | EEERVADKEE | RRKTEALSEI | 
    500:
    EVLREAQEPS | GPLMLSSELS | LEVAEEEKSR | TSFIPPEERW | AWIEERQPEP | 
    550:
    PALPMLPELP | EVPMEMPPGP | ELLSSEAVLR | AVALELQANR | EPDFSSLVPP | 
    593:
    LSSRKLASRV | FYLLLVLSAQ | KILLVDQQKP | YGRLLIRLGP | KFP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Meiotic recombination protein REC8 homolog
    Cat.:
    E4955h
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Rat Meiotic recombination protein REC8 homolog
    Cat.:
    E4955m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Rat Meiotic recombination protein REC8 homolog
    Cat.:
    E4955r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Meiotic recombination protein REC8 homolog
    Cat.:
    U4955r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Meiotic recombination protein REC8 homolog
    Cat.:
    U4955h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Meiotic recombination protein REC8 homolog
    Cat.:
    U4955m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Meiotic recombination protein REC8 homolog
    Cat.:
    P4955Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Meiotic recombination protein REC8 homolog
    Cat.:
    P4955Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Meiotic recombination protein REC8 homolog
    Cat.:
    P4955Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Meiotic recombination protein REC8 homolog
    Monoclonal Antibody for Rat Meiotic recombination protein REC8 homolog
    Monoclonal Antibody for Rat Meiotic recombination protein REC8 homolog
    Protein for Rat Meiotic recombination protein REC8 homolog
    Protein for Rat Meiotic recombination protein REC8 homolog
    Protein for Rat Meiotic recombination protein REC8 homolog

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    Precision
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    Linearity
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    References
    1. 1.
      "Rat Rec8 mRNA full sequence."
      Ben-Ari V. , Dekel N.
      Submitted (2004-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Wistar.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Brown Norway.
      tissue: Testis.
    3. 3.
      "Meiotic cohesin REC8 marks the axial elements of rat synaptonemal complexes before cohesins SMC1beta and SMC3."
      Eijpe M. , Offenberg H. , Jessberger R. , Revenkova E. , Heyting C.
      J. Cell Biol.160:657-670(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RAD51;SUBCELLULAR LOCATION;PHOSPHORYLATION
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