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Index > Protein center > RLN3(Gene name) > Human
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  • RLN3 (Gene name),
  • Relaxin-3 (Protein name ),  REL3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    RLN3(UNQ6188/PRO20213;INSL7;RXN3;ZINS4);
    Protein name:
    Relaxin-3;
    Alternative:
    Prorelaxin H3;Insulin-like peptide INSL7(Insulin-like peptide 7);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Heterodimer of a B chain and an A chain linked by two disulfide bonds.
    Function:
    May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 (GPCR135) and relaxin-3 receptor-2 (GPCR142).
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    142
    Sequence:
    50:
    MARYMLLLLL | AVWVLTGELW | PGAEARAAPY | GVRLCGREFI | RAVIFTCGGS | 
    100:
    RWRRSDILAH | EAMGDTFPDA | DADEDSLAGE | LDEAMGSSEW | LALTKSPQAF | 
    142:
    YRGRPSWQGT | PGVLRGSRDV | LAGLSSSCCK | WGCSKSEISS | LC
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    SMR:
    UniGene:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Relaxin-3
    Cat.:
    E0189h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Relaxin-3
    Cat.:
    E0189m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Relaxin-3
    Cat.:
    E0189r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Relaxin-3
    Cat.:
    E0189p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Relaxin-3
    Cat.:
    U0189r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Relaxin-3
    Cat.:
    U0189h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Relaxin-3
    Cat.:
    U0189m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Relaxin-3
    Cat.:
    U0189p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Relaxin-3
    Cat.:
    P0189Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Relaxin-3
    Cat.:
    P0189Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Relaxin-3
    Cat.:
    P0189Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Relaxin-3
    Monoclonal Antibody for Human Relaxin-3
    Monoclonal Antibody for Human Relaxin-3
    Monoclonal Antibody for Human Relaxin-3
    Monoclonal Antibody for Human Relaxin-3
    Protein for Human Relaxin-3
    Protein for Human Relaxin-3
    Protein for Human Relaxin-3
    Protein for Human Relaxin-3

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    Citations
    [1].
    Maivel H. Ghattas, Eman T. Mehanna, Noha M. Mesbah, Dina M. Abo-Elmatty
    References
    1. 1.
      "Homo sapiens insulin homolog polypeptide."
      Holloway J.L. , Lok S. , Jaspers S.R.
      Submitted (2001-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 26-34 AND 119-127
    3. 3.
      "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
      Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
      Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    4. 4.
      "H3 relaxin is a specific ligand for LGR7 and activates the receptor by interacting with both the ectodomain and the exoloop 2."
      Sudo S. , Kumagai J. , Nishi S. , Layfield S. , Ferraro T. , Bathgate R.A.D. , Hsueh A.J.W.
      J. Biol. Chem.278:7855-7862(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH LGR7
    5. 5.
      "Identification of relaxin-3/INSL7 as an endogenous ligand for the orphan G-protein coupled receptor GPCR135."
      Liu C. , Eriste E. , Sutton S. , Chen J. , Roland B. , Kuei C. , Farmer N. , Joernvall H. , Sillard R. , Lovenberg T.W.
      J. Biol. Chem.278:50754-50764(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH GPCR135
    6. 6.
      "Identification of relaxin-3/INSL7 as a ligand for GPCR142."
      Liu C. , Chen J. , Sutton S. , Roland B. , Kuei C. , Farmer N. , Sillard R. , Lovenberg T.W.
      J. Biol. Chem.278:50765-50770(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH GPCR142
    7. 7.
      "Solution structure and novel insights into the determinants of the receptor specificity of human relaxin-3."
      Rosengren K.J. , Lin F. , Bathgate R.A. , Tregear G.W. , Daly N.L. , Wade J.D. , Craik D.J.
      J. Biol. Chem.281:5845-5851(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 26-142;DISULFIDE BONDS
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