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Index > Protein center > Rasd2(Gene name) > Rat
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  • Rasd2 (Gene name),
  • GTP-binding protein Rhes (Protein name ),  RHES_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Rasd2;
    Protein name:
    GTP-binding protein Rhes;
    Alternative:
    SE6C;Ras homolog enriched in striatum;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Monomer (Potential). Interacts with GNB1, GNB2 and GNB3 (By similarity). Interacts with PIK3CA and UBE2I.
    Function:
    GTPase signaling protein that binds to and hydrolyzes GTP. Regulates signaling pathways involving G-proteins-coupled receptor and heterotrimeric proteins such as GNB1, GNB2 and GNB3. May be involved in selected striatal competencies, mainly locomotor activity and motor coordination.
    Subcellular Location:
    Cell membrane Lipid-anchor Found in granular structures throughout the cytosol.
    Protein Attributes:
    Sequence length:
    266
    Sequence:
    50:
    MMKTLSSGNC | TLNVPAKNSY | RMVVLGASRV | GKSSIVSRFL | NGRFEDQYTP | 
    100:
    TIEDFHRKVY | NIHGDMYQLD | ILDTSGNHPF | PAMRRLSILT | GDVFILVFSL | 
    150:
    DSRESFDEVK | RLQKQILEVK | SCLKNKTKEA | AELPMVICGN | KNDHSELCRQ | 
    200:
    VPAMEAELLV | SGDENCAYFE | VSAKKNTNVN | EMFYVLFSMA | KLPHEMSPAL | 
    250:
    HHKISVQYGD | AFHPRPFCMR | RTKVAGAYGM | VSPFARRPSV | NSDLKYIKAK | 
    266:
    VLREGQARER | DKCSIQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat GTP-binding protein Rhes
    Cat.:
    E3228h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Rat GTP-binding protein Rhes
    Cat.:
    E3228r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Rat GTP-binding protein Rhes
    Cat.:
    E3228m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat GTP-binding protein Rhes
    Cat.:
    U3228m
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat GTP-binding protein Rhes
    Cat.:
    U3228h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat GTP-binding protein Rhes
    Cat.:
    U3228r
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Rat GTP-binding protein Rhes
    Cat.:
    P3228Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat GTP-binding protein Rhes
    Cat.:
    P3228Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat GTP-binding protein Rhes
    Cat.:
    P3228Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat GTP-binding protein Rhes
    Monoclonal Antibody for Rat GTP-binding protein Rhes
    Monoclonal Antibody for Rat GTP-binding protein Rhes
    Protein for Rat GTP-binding protein Rhes
    Protein for Rat GTP-binding protein Rhes
    Protein for Rat GTP-binding protein Rhes

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    Precision
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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY;GTP-BINDING
      strain: Sprague-Dawley.
      tissue: Corpus striatum.
    2. 2.
      "Identification of the monomeric G-protein, Rhes, as an efaroxan-regulated protein in the pancreatic beta-cell."
      Chan S.L.F. , Monks L.K. , Gao H. , Deaville P. , Morgan N.G.
      Br. J. Pharmacol.136:31-36(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION
    3. 3.
      "Thyroid hormone regulation of rhes, a novel Ras homolog gene expressed in the striatum."
      Vargiu P. , Morte B. , Manzano J. , Perez J. , de Abajo R. , Sutcliffe J.G. , Bernal J.
      Brain Res. Mol. Brain Res.94:1-8(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;INDUCTION BY THYROID HORMONE
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    5. 5.
      "The small GTP-binding protein, Rhes, regulates signal transduction from G protein-coupled receptors."
      Vargiu P. , De Abajo R. , Garcia-Ranea J.A. , Valencia A. , Santisteban P. , Crespo P. , Bernal J.
      Oncogene23:559-568(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;GTP-BINDING;SUBCELLULAR LOCATION;ISOPRENYLATION AT CYS-263;MUTAGENESIS OF CYS-263;INTERACTION WITH PIK3CA
    6. 6.
      "Rhes expression in pancreatic beta-cells is regulated by efaroxan in a calcium-dependent process."
      Taylor J.P. , Jackson D.A. , Morgan N.G. , Chan S.L.
      Biochem. Biophys. Res. Commun.349:809-815(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;INDUCTION BY EFAROXAN AND GLIBENCLAMIDE
    7. 7.
      "Ontogeny and dopaminergic regulation in brain of Ras homolog enriched in striatum (Rhes)."
      Harrison L.M. , Lahoste G.J. , Ruskin D.N.
      Brain Res.1245:16-25(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY
    8. 8.
      "Rhes, a striatal specific protein, mediates mutant-huntingtin cytotoxicity."
      Subramaniam S. , Sixt K.M. , Barrow R. , Snyder S.H.
      Science324:1327-1330(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH UBE2I;SUBCELLULAR LOCATION;MUTAGENESIS OF CYS-263
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