Protein name:
RecQ-mediated genome instability protein 2 ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Component of the RMI complex, containing at least TOP3A, RMI1 and RMI2. The RMI complex interacts with BLM.
Function:
Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. The complex is therefore essential for the stability, localization, and function of complexes containing BLM. In the RMI complex, it is required to target BLM to chromatin and stress-induced nuclear foci and mitotic phosphorylation of BLM.
Subcellular Location:
Nucleus
Colocalizes with BLM at nuclear DNA repair foci.
Protein Attributes:
50:
MAAAASESLS | SGGPGAVRLP | RLPPLKVLAG | QLRRHAEGGP | GAWRLSRAAV |
100:
GRAPLELVAV | WMQGTVLAAE | GGQARLRDSS | GAFSVRGLER | VPRGRPCLLP |
149:
GKYVMVMGVV | QACSPEPCLQ | AVKMTDLSDN | PVHESMWELE | VEDLHRNIP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Bovine
Chicken
ELISA Kit for Mouse RecQ-mediated genome instability protein 2
ELISA Kit for Mouse RecQ-mediated genome instability protein 2
ELISA Kit for Mouse RecQ-mediated genome instability protein 2
ELISA Kit for Mouse RecQ-mediated genome instability protein 2
CLIA Kit for Mouse RecQ-mediated genome instability protein 2
CLIA Kit for Mouse RecQ-mediated genome instability protein 2
CLIA Kit for Mouse RecQ-mediated genome instability protein 2
CLIA Kit for Mouse RecQ-mediated genome instability protein 2
Polyclonal Antibody for Mouse RecQ-mediated genome instability protein 2
Polyclonal Antibody for Mouse RecQ-mediated genome instability protein 2
Polyclonal Antibody for Mouse RecQ-mediated genome instability protein 2
Polyclonal Antibody for Mouse RecQ-mediated genome instability protein 2
Monoclonal Antibody for Mouse RecQ-mediated genome instability protein 2
Monoclonal Antibody for Mouse RecQ-mediated genome instability protein 2
Monoclonal Antibody for Mouse RecQ-mediated genome instability protein 2
Monoclonal Antibody for Mouse RecQ-mediated genome instability protein 2
Protein for Mouse RecQ-mediated genome instability protein 2
Protein for Mouse RecQ-mediated genome instability protein 2
Protein for Mouse RecQ-mediated genome instability protein 2
Protein for Mouse RecQ-mediated genome instability protein 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
strain :
C57BL/6J .
tissue :
Spleen .
tissue :
Thymus .