Protein name:
E3 ubiquitin-protein ligase RNF123 ;
Alternative:
RING finger protein 123 ;Kip1 ubiquitination-promoting complex protein 1 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Component of the KPC complex composed of RNF123/KPC1 and UBAC1/KPC2. Interacts with UBAC1 and CDKN1B via its N-terminal domain.
Function:
Catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MTSKGAAMSF | SRKSYRLTSD | AEKSRVTGIV | QEKLLSDYLY | RIFSSPDHGT |
100:
PAATSRKPLN | FHNLPEHVDQ | LLQVDDEESQ | GQVEGRLGPS | TVVLDHTGGF |
150:
EGLLLVDDDL | LGVIGHSNFG | TIRSSTCVYK | GKWVYEVLIS | SQGLMQIGWC |
200:
TINCRFNQEE | GVGDTHNSYA | YDGNRVRKWN | VTTTNYGKAW | AAGDIVSCLI |
250:
DLDDGTLSFC | LNGVSLGTAF | ENLSRGLGMA | YFPAISLSFK | ESVAFNFGSR |
300:
PLRYPVAGFR | PLQDPPFADL | VRAQRLLGCF | QTVLSVELDP | VEGRLVEKES |
350:
SEWQLHGQPT | VLLTLAHIFH | HFAPLLRKVY | LVEAVLMSFL | LGIVEKGTPE |
400:
QAQSVVHQIL | DLLWLFMEDY | EVQDCLKQLM | MSLLRLYRFS | PIVPDLGLQI |
450:
HYLRLTMAVL | RHEKSRKFLL | SNVLFDMLRS | VVFFYIKSPL | RVEEAGLKEL |
500:
IPTTWWPHRS | SREGRDGQEA | KEETTEERQR | RRAYERGCQR | LKKRIEVVEE |
550:
LQVQILKLLL | DNKDDNGGEA | SRYIFLTKFR | KFLQENASGR | GNTPVLCPPE |
600:
YMVCFLHRLV | SALRFYWDEY | KASNPRASFS | DEAYIPPQIF | YNGKVDYFDL |
650:
QRLGGLLSHL | RKTLKDDLAS | KANIVIDPLE | LQAATMDDLD | EDEEPAPTAA |
700:
QSWRARQRPV | QALAIGGALP | LPRPGWLSSP | TLGRANRFLS | TAAVSLMTPR |
750:
RLLSTMEKVK | VRSLNVEQRT | REDIEGSHWN | EGLLLGRPPE | EPERPLTENS |
800:
LLEVLDGTVM | MYSLSVHQQL | GKMVGVSDDV | NEYAMALRDT | EDKLRRCPKR |
850:
RKDILAELTK | SQKVFSEKLD | HLSRRLAWVH | ATVYSQEKML | DIYWLLRVCL |
900:
QTIEHGDRTG | SLFAFMPEFY | LSVAINSYSA | LKNYFGPVHS | MEELPGYEET |
950:
LTRLAAILAK | HFADPRIVGT | DIRDSLMQAL | ASYVCYPHSL | RAVERIPEEQ |
1000:
RIAMVRNLLA | PYEQRPWAQT | NWILVRLWRG | CGFGYRYTRL | PHLLKTKPED |
1050:
ANLPSLQKPC | PSTLLQQHMA | DLLRQGSDVA | PSFLNSVLNQ | LNWAFSEFIG |
1100:
MIQEIQQAAE | RLERNFVDSR | QLKVCATCFD | LSVSLLRVLE | MTITLVPEIF |
1150:
LDWSRPTSEM | LLRRLAQLLN | QVLNRVTAER | NLFDRVVTLR | LPGLESVDHY |
1200:
PILVAVTGIL | VRLLAHGPSS | ETEQATSVLL | ADPCFQLRSI | RYLLGQPEPL |
1250:
APGSALPAPD | RKRFSLQSYA | DYISAEELAQ | VERMLAHLTA | ASAQAAAASL |
1300:
PTNEEDLCPI | CYAHPISAVF | QPCGHKSCKA | CINQHLMNNK | DCFFCKATIV |
1318:
SVEDWDKAAS | TSATSSAA
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
ELISA Kit for Rat E3 ubiquitin-protein ligase RNF123
ELISA Kit for Rat E3 ubiquitin-protein ligase RNF123
ELISA Kit for Rat E3 ubiquitin-protein ligase RNF123
CLIA Kit for Rat E3 ubiquitin-protein ligase RNF123
CLIA Kit for Rat E3 ubiquitin-protein ligase RNF123
CLIA Kit for Rat E3 ubiquitin-protein ligase RNF123
Polyclonal Antibody for Rat E3 ubiquitin-protein ligase RNF123
Polyclonal Antibody for Rat E3 ubiquitin-protein ligase RNF123
Polyclonal Antibody for Rat E3 ubiquitin-protein ligase RNF123
Monoclonal Antibody for Rat E3 ubiquitin-protein ligase RNF123
Monoclonal Antibody for Rat E3 ubiquitin-protein ligase RNF123
Monoclonal Antibody for Rat E3 ubiquitin-protein ligase RNF123
Protein for Rat E3 ubiquitin-protein ligase RNF123
Protein for Rat E3 ubiquitin-protein ligase RNF123
Protein for Rat E3 ubiquitin-protein ligase RNF123
R&D Technical Data
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Precision
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Recovery
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Linearity
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more...
Nature428:493-521(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
Brown Norway .
2.
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Cited for : UBIQUITINATION;DEUBIQUITINATION BY USP19