Rnf146 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comRnf146 ELISA Kit for Rat(Rattus norvegicus)

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Rnf146 (Gene name),

E3 ubiquitin-protein ligase RNF146 (Protein name ), RN146_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Rnf146;

Protein name:

E3 ubiquitin-protein ligase RNF146;

Alternative:

RING finger protein 146;RING finger protein 146;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with poly-ADP-ribosylated AXIN1, AXIN2, BLZF1 and CASC3.

Function:

E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation. Acts as an activator of the Wnt signaling pathway by mediating the ubiquitination of poly-ADP-ribosylated AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex. Acts in cooperation with tankyrase proteins (TNKS and TNKS2), which mediate poly-ADP-ribosylation of target proteins AXIN1, AXIN2, BLZF1, CASC3, TNKS and TNKS2. Recognizes and binds tankyrase-dependent poly-ADP-ribosylated proteins via its WWE domain and mediates their ubiquitination.

Subcellular Location:

Cytoplasm cytosol

Protein Attributes:

Sequence length:

352

Sequence:

50:

100:

150:

200:

250:

300:

350:

352:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.167060

String:

Q5XIK5

Pfam:

PF02825

SMR:

Q5XIK5

STRING:

10116.ENSRNOP00000015421

KEGG:

rno:308051

Uniprot:

Q5XIK5

FOR

ELISA Kit for Rat E3 ubiquitin-protein ligase RNF146

CLIA Kit for Rat E3 ubiquitin-protein ligase RNF146

Polyclonal Antibody for Rat E3 ubiquitin-protein ligase RNF146

Monoclonal Antibody for Rat E3 ubiquitin-protein ligase RNF146

Protein for Rat E3 ubiquitin-protein ligase RNF146

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Testis.

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