RNF168 ELISA Kit for Bovine(Bos taurus) | EIAab.comRNF168 ELISA Kit for Bovine(Bos taurus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > RNF168(Gene name) > Bovine

RNF168 (Gene name),

E3 ubiquitin-protein ligase RNF168 (Protein name ), RN168_BOVIN from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

RNF168;

Protein name:

E3 ubiquitin-protein ligase RNF168;

Alternative:

RING finger protein 168;

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

Interacts with UBE2N/UBC13.

Function:

E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the RNF8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1.

Subcellular Location:

Nucleus Localizes to sites of DNA damage.

Protein Attributes:

Sequence length:

573

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

573:

TAHSLQPSKS | QKSIFQMFQR | VTK

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

KEGG:

bta:613812

UniGene:

Bt.6014

String:

Q0IIM1

Pfam:

PF00097

STRING:

9913.ENSBTAP00000017712

Uniprot:

Q0IIM1

FOR

ELISA Kit for Bovine E3 ubiquitin-protein ligase RNF168

CLIA Kit for Bovine E3 ubiquitin-protein ligase RNF168

Polyclonal Antibody for Bovine E3 ubiquitin-protein ligase RNF168

Monoclonal Antibody for Bovine E3 ubiquitin-protein ligase RNF168

Protein for Bovine E3 ubiquitin-protein ligase RNF168

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The genome sequence of taurine cattle: a window to ruminant biology and evolution."
The bovine genome sequencing and analysis consortium
Science324:522-528(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: Hereford.
2.

NIH - Mammalian Gene Collection (MGC) project
Submitted (2006-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
strain: Hereford.
tissue: Thalamus.

Product Feedback Wall

* Email:
*Comments: