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Index > Protein center > Slc6a15(Gene name) > Mouse
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  • Slc6a15 (Gene name),
  • Sodium-dependent neutral amino acid transporter B(0)AT2 (Protein name ),  S6A15_MOUSE from NCBI database.
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  • General Annotation
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  • Gene name:
    Slc6a15(B0at2;Ntt73);
    Protein name:
    Sodium-dependent neutral amino acid transporter B(0)AT2;
    Alternative:
    Solute carrier family 6 member 15;Sodium- and chloride-dependent neurotransmitter transporter NTT73;Transporter v7-3;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for methionine and for the branched-chain amino acids, particulary leucine, valine and isoleucine. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1:1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    729
    Sequence:
    50:
    MPKNSKVVKR | DLDDDVIESV | KDLLSNEDSV | EEVSKKSELI | VDVQEEKDTD | 
    100:
    AEDGSEADDE | RPAWNSKLQY | ILAQVGFSVG | LGNVWRFPYL | CQKNGGGAYL | 
    150:
    LPYLILLLVI | GIPLFFLELS | VGQRIRRGSI | GVWNYISPKL | GGIGFASCVV | 
    200:
    CYFVALYYNV | IIGWTLFYFS | QSFQQPLPWD | QCPLVKNASH | TYVEPECEQS | 
    250:
    SATTYYWYRE | ALDITSSISD | SGGLNWKMTV | CLLVAWVMVC | LAMIKGIQSS | 
    300:
    GKIMYFSSLF | PYVVLICFLI | RSLLLNGSID | GIRHMFTPKL | EMMLEPKVWR | 
    350:
    EAATQVFFAL | GLGFGGVIAF | SSYNKRDNNC | HFDAVLVSFI | NFFTSVLATL | 
    400:
    VVFAVLGFKA | NIVNEKCISQ | NSEMILKLLK | MGNISWDVIP | HHINLSAVTV | 
    450:
    EDYRLVYDII | QKVKEEEFAV | LHLNACQIED | ELNKAVQGTG | LAFIAFTEAM | 
    500:
    THFPASPFWS | VMFFLMLINL | GLGSMFGTIE | GIITPIVDTF | KVRKEILTVI | 
    550:
    CCLLAFCIGL | IFVQRSGNYF | VTMFDDYSAT | LPLLIVVILE | NIAVSFVYGI | 
    600:
    DKFIEDLTDM | LGFAPSKYYY | YMWKYISPLM | LLTLLIASIV | NMGLSPPGYN | 
    650:
    AWIKEKASEE | FLSYPMWGMV | VCFSLMVLAI | LPVPVVFIIR | RCNLIDDSSG | 
    700:
    NLASVTYKRG | RVLKEPVNLE | GDDASLIHGK | IPSEMSSPNF | GKNIYRKQSG | 
    729:
    SPTLDTAPNG | RYGIGYLMAD | MPDMPESDL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Sodium-dependent neutral amino acid transporter B(0)AT2
    Cat.:
    E5257h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse Sodium-dependent neutral amino acid transporter B(0)AT2
    Cat.:
    E5257m
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    Packing:
    96T
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    ELISA Kit for Mouse Sodium-dependent neutral amino acid transporter B(0)AT2
    Cat.:
    E5257r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse Sodium-dependent neutral amino acid transporter B(0)AT2
    Cat.:
    E5257b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Sodium-dependent neutral amino acid transporter B(0)AT2
    Cat.:
    U5257b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Sodium-dependent neutral amino acid transporter B(0)AT2
    Cat.:
    U5257m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Sodium-dependent neutral amino acid transporter B(0)AT2
    Cat.:
    U5257h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Sodium-dependent neutral amino acid transporter B(0)AT2
    Cat.:
    U5257r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Sodium-dependent neutral amino acid transporter B(0)AT2
    Cat.:
    P5257Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Sodium-dependent neutral amino acid transporter B(0)AT2
    Polyclonal Antibody for Mouse Sodium-dependent neutral amino acid transporter B(0)AT2
    Cat.:
    P5257Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Sodium-dependent neutral amino acid transporter B(0)AT2
    Cat.:
    P5257Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Sodium-dependent neutral amino acid transporter B(0)AT2
    Monoclonal Antibody for Mouse Sodium-dependent neutral amino acid transporter B(0)AT2
    Monoclonal Antibody for Mouse Sodium-dependent neutral amino acid transporter B(0)AT2
    Monoclonal Antibody for Mouse Sodium-dependent neutral amino acid transporter B(0)AT2
    Protein for Mouse Sodium-dependent neutral amino acid transporter B(0)AT2
    Protein for Mouse Sodium-dependent neutral amino acid transporter B(0)AT2
    Protein for Mouse Sodium-dependent neutral amino acid transporter B(0)AT2
    Protein for Mouse Sodium-dependent neutral amino acid transporter B(0)AT2

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Mouse sodium-dependent orphan neurotransmitter transporter V73 cDNA."
      Liu Q.-R. , Uhl G.R.
      Submitted (2002-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: C57BL/6.
    2. 2.
      "Characterization of orphan neurotransmitter transporter V73 genomic structure."
      Liu Q.-R. , Uhl G.R.
      Submitted (2002-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
      strain: 129/SvJ.
    3. 3.
      "The orphan transporter v7-3 (slc6a15) is a Na+-dependent neutral amino acid transporter (B0AT2)."
      Broer A. , Tietze N. , Kowalczuk S. , Chubb S. , Munzinger M. , Bak L.K. , Broer S.
      Biochem. J.393:421-430(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;BIOPHYSICOCHEMICAL PROPERTIES;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
      strain: C57BL/6.
      tissue: Brain.
    4. 4.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Cerebellum.
    5. 5.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6.
      tissue: Eye.
    7. 7.
      "Deletion of v7-3 (SLC6A15) transporter allows assessment of its roles in synaptosomal proline uptake, leucine uptake and behaviors."
      Drgonova J. , Liu Q.R. , Hall F.S. , Krieger R.M. , Uhl G.R.
      Brain Res.1183:10-20(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
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