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Index > Protein center > SLC5A11(Gene name) > Pig
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  • SLC5A11 (Gene name),
  • Sodium/myo-inositol cotransporter 2 (Protein name ),  SC5AB_PIG from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    SLC5A11(SMIT2);
    Protein name:
    Sodium/myo-inositol cotransporter 2(Na(+)/myo-inositol cotransporter 2);
    Alternative:
    Solute carrier family 5 member 11;Solute carrier family 5 member 11(SMIT2);
    Organism:
    Pig (Sus scrofa). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Involved in the sodium-dependent cotransport of myo-inositol (MI) with a Na(+):MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and absorption in intestine. Also can transport D-chiro-inositol (DCI) but not L-fructose. Exhibits stereospecific cotransport of both D-glucose and D-xylose. May induce apoptosis through the TNF-alpha, PDCD1 pathway. May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    674
    Sequence:
    50:
    MESSPSSPQP | TQSDPLAVFP | QRTLEPADIA | VLVLYFLFVL | AVGLWSTVKT | 
    100:
    RRDTVKGYFL | AGGDMVWWPV | GASLFASNVG | SGHFVGLAGS | GAAAGLSVTA | 
    150:
    YEFNGIFSVL | MLAWIFLPIY | IAGQVTTMPE | YLRKRFGGSR | IPITLAVLYL | 
    200:
    FIYIFTKISV | DMYAGAIFIQ | QSLHLNLYLA | IVGLLAITAL | YTIAGGLAAV | 
    250:
    IYTDALQTLI | MLIGALTLMG | YSFAAVGGME | GLKEKYFLAL | ASNRSGNSSC | 
    300:
    GLPREDAFHI | FRDPLTSDLP | WPGILFGMSI | PSLWYWCTDQ | VIVQRTLAAK | 
    350:
    NLSHAKGGSL | MAAYLKVLPL | FIMVFPGMVS | RVLFPDQVAC | ADPEICQKVC | 
    400:
    SNPAGCSDIA | YPKLVLELLP | MGLRGLMMAV | MVAALMSSLT | SIFNSASTIF | 
    450:
    TMDLWNHLRP | RASERELMIV | GRVFVLLLVL | VSILWIPVVQ | ASQGGQLFIY | 
    500:
    IQSISSYLQP | PVAVVFIMGC | FWKRTNEKGA | FSGLILGLLL | GLVRLVLDFI | 
    550:
    YPQPRCDQPD | ERPAVVRDVH | YLYFSMILSS | VTLVTVSTVS | WCTAPPTQEM | 
    600:
    VSRLTWFTRH | DPIVLKEQVP | SATPVPVTVS | QNGTPEASST | NIQFEIVQEN | 
    650:
    TSKTHSCDMT | KKQSKVVKTI | LWLCGMESKG | KEEPPSRADP | VIVSLEEIPL | 
    674:
    VKTLLDINLI | VCISCAIFLW | GYFA
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Pig Na(+)/myo-inositol cotransporter 2
    ELISA Kit for Pig Na(+)/myo-inositol cotransporter 2
    ELISA Kit for Pig Na(+)/myo-inositol cotransporter 2
    ELISA Kit for Pig Na(+)/myo-inositol cotransporter 2
    ELISA Kit for Pig Na(+)/myo-inositol cotransporter 2
    ELISA Kit for Pig Na(+)/myo-inositol cotransporter 2
    CLIA Kit for Pig Na(+)/myo-inositol cotransporter 2
    CLIA Kit for Pig Na(+)/myo-inositol cotransporter 2
    CLIA Kit for Pig Na(+)/myo-inositol cotransporter 2
    CLIA Kit for Pig Na(+)/myo-inositol cotransporter 2
    CLIA Kit for Pig Na(+)/myo-inositol cotransporter 2
    CLIA Kit for Pig Na(+)/myo-inositol cotransporter 2
    Polyclonal Antibody for Pig Na(+)/myo-inositol cotransporter 2
    Polyclonal Antibody for Pig Na(+)/myo-inositol cotransporter 2
    Polyclonal Antibody for Pig Na(+)/myo-inositol cotransporter 2
    Polyclonal Antibody for Pig Na(+)/myo-inositol cotransporter 2
    Polyclonal Antibody for Pig Na(+)/myo-inositol cotransporter 2
    Polyclonal Antibody for Pig Na(+)/myo-inositol cotransporter 2
    Monoclonal Antibody for Pig Na(+)/myo-inositol cotransporter 2
    Monoclonal Antibody for Pig Na(+)/myo-inositol cotransporter 2
    Monoclonal Antibody for Pig Na(+)/myo-inositol cotransporter 2
    Monoclonal Antibody for Pig Na(+)/myo-inositol cotransporter 2
    Monoclonal Antibody for Pig Na(+)/myo-inositol cotransporter 2
    Monoclonal Antibody for Pig Na(+)/myo-inositol cotransporter 2
    Protein for Pig Na(+)/myo-inositol cotransporter 2
    Protein for Pig Na(+)/myo-inositol cotransporter 2
    Protein for Pig Na(+)/myo-inositol cotransporter 2
    Protein for Pig Na(+)/myo-inositol cotransporter 2
    Protein for Pig Na(+)/myo-inositol cotransporter 2
    Protein for Pig Na(+)/myo-inositol cotransporter 2

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    References
    1. 1.
      "The Na+/myo-inositol cotransporters SMIT1 and SMIT2 are not regulated by tonicity in the renal cell line LLC-PK1."
      Coady M.J. , Bissonnette P. , Wallendorff B. , Lapointe J.-Y.
      Submitted (2007-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
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