Kitlg ELISA Kit for Rat(Rattus norvegicus) | EIAab.comKitlg ELISA Kit for Rat(Rattus norvegicus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Kitlg(Gene name) > Rat

Kitlg (Gene name),

Kit ligand (Protein name ), SCF_RAT from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (1)

Feedback

Gene name:

Kitlg(Kitl;Mgf);

Protein name:

Kit ligand;

Alternative:

Mast cell growth factor(MGF);Hematopoietic growth factor KL;c-Kit ligand;Stem cell factor(SCF);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Homodimer, non-covalently linked (Probable). Heterotetramer with KIT, binding two KIT molecules; thereby mediates KIT dimerization and subsequent activation by autophosphorylation.

Function:

Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol-1,4,5-trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins.

Subcellular Location:

Soluble KIT ligand Secreted

Protein Attributes:

Sequence length:

273

Sequence:

50:

100:

150:

200:

250:

273:

IQINEEDNEI | SMLQQKEREF | QEV

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

KEGG:

rno:60427

Pfam:

PF02404

String:

P21581

UniGene:

Rn.44216

SMR:

P21581

Uniprot:

P21581

FOR

ELISA Kit for Rat Kit ligand

Cat.:

E0120r

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Rat Kit ligand

Cat.:

E0120h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Rat Kit ligand

Cat.:

E0120m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Rat Kit ligand

Cat.:

E0120b

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Rat Kit ligand

Cat.:

E0120c

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Rat Kit ligand

Cat.:

E0120d

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Rat Kit ligand

Cat.:

E0120p

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat Kit ligand

Cat.:

U0120p

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat Kit ligand

Cat.:

U0120c

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat Kit ligand

Cat.:

U0120d

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat Kit ligand

Cat.:

U0120r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat Kit ligand

Cat.:

U0120h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat Kit ligand

Cat.:

U0120b

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Rat Kit ligand

Cat.:

U0120m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Rat Kit ligand

Cat.:

P0120Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Kit ligand

Cat.:

P0120Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Kit ligand

Cat.:

P0120Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Kit ligand

Monoclonal Antibody for Rat Kit ligand

Protein for Rat Kit ligand

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Citations

[1].

"The Neuroprotective Effect Exerted by Oligodendroglial Progenitors on Ischemically Impaired Hippocampal Cells"

J Sypecka, A Sarnowska

From:Molecular neurobiology

References

1.

Teramoto T. , Nagashima M. , Thorgeirsson S.S.
Submitted (1998-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
2.

"Primary structure and functional expression of rat and human stem cell factor DNAs."
Martin F.H. , Suggs S.V. , Langley K.E. , Lu H.S. , Ting J. , Okino K.H. , Morris C.F. , McNiece I.K. , Jacobsen F.W. , Mendiaz E.A. , Birkett N.C. , Smith K.A. , Johnson M.J. , Parker V.P. , Flores J.C. , Patel A.C. , Fisher E.F. , Erjavec H.O. , more...
Cell63:203-211(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-201;PARTIAL PROTEIN SEQUENCE
3.

"Amino acid sequence and post-translational modification of stem cell factor isolated from buffalo rat liver cell-conditioned medium."
Lu H.S. , Clogston C.L. , Wypych J. , Fausset P.R. , Lauren S. , Mendiaz E.A. , Zsebo K.M. , Langley K.E.
J. Biol. Chem.266:8102-8107(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 26-190;PYROGLUTAMATE FORMATION AT GLN-26;GLYCOSYLATION AT ASN-90; ASN-134; ASN-145; SER-167; THR-168; THR-180 AND ASN-195;DISULFIDE BONDS
strain: Buffalo.
tissue: Liver.
4.

"Identification, purification, and biological characterization of hematopoietic stem cell factor from buffalo rat liver-conditioned medium."
Zsebo K.M. , Wypych J. , McNiece I.K. , Lu H.S. , Smith K.A. , Karkare S.B. , Sachdev R.K. , Yuschenkoff V.N. , Birkett N.C. , Williams L.R. , Satyagal V.N. , Tung W. , Bosselman R.A. , Mendiaz E.A. , Langley K.E.
Cell63:195-201(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 26-39

Product Feedback Wall

* Email:
*Comments: